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Starting SUD treatment offers the opportunity to also quit smoking. The ACT-ATAC project aims to identify the predictors associated with smoking cessation among persons treated for alcohol and\/or cannabis use disorder in Barcelona. This manuscript reports its methodology and the experience of carrying it out during the COVID-19 pandemic.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Mixed methods project with three substudies. Substudy 1 (S1) comprises heterogeneous discussion groups among clinicians. S2 has two prospective cohorts composed of smokers under treatment for alcohol and\/or cannabis use disorder and the clinicians in charge of these patients. Participating smokers will be followed for 12\u00a0months and interviewed about their substance use and the tobacco cessation services received using the Spanish version of the users\u2019 Knowledge, Attitudes, and Services (S-KAS) scale. The clinicians will be asked about their self-reported practices in smoking cessation using the Knowledge, Attitudes, and Practices (S-KAP) scale. S3 comprises heterogeneous discussion groups with smokers. Data will be triangulated using qualitative and quantitative analyses. To facilitate the recruitment process, the researchers have introduced several strategies (design clear protocols, set monthly online meetings, extend the project, provide gift cards, etc.).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Discussion<\/jats:title>\n                <jats:p>The results of S1 were used to develop the questionnaires. S2 required some adjustments due to the COVID-19 pandemic, particularly the follow-up interviews being conducted by phone instead of face-to-face, and the recruitment rhythm was lower than expected. Recruitment will last until reaching at least 200\u2013250 users. The fieldwork could not have been possible without the collaboration of the ACT-ATAC team and the introduction of several strategies.<\/jats:p>\n                <jats:p><jats:bold><jats:italic>Trial registration<\/jats:italic><\/jats:bold> The ACT-ATAC project has been successfully registered at Clinicaltrials.gov [NCT04841655].<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13722-022-00348-9","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T08:04:50Z","timestamp":1669795490000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Tobacco cessation among smokers under substance use treatment for alcohol and\/or cannabis: study protocol and pilot 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