{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T05:32:03Z","timestamp":1773466323748,"version":"3.50.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:00:00Z","timestamp":1629331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:00:00Z","timestamp":1629331200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"the 136 Medical Rejuvenation Project of Shanxi Province"},{"name":"the health research project of Health Commission of Shanxi Province","award":["2018046"],"award-info":[{"award-number":["2018046"]}]},{"name":"the soft science research plan project of the Shanxi Science and Technology Department","award":["2018041029\u20136"],"award-info":[{"award-number":["2018041029\u20136"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Perioper Med"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Functional endoscopic sinus surgery (FESS) is required to minimize bleeding to maintain a clear operative field during surgery, so it is important to preoperative anti-anxiety and stable hemodynamics. Initial evidence suggests cognitive behavioral therapy (CBT) is effective to minimize surgery-related stress and to speed up recovery. The study aimed to evaluate the efficacy of a newly developed computer-assisted CBT (cCBT) program on surgery-related psychobiological responses in patients undergoing FESS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Participants were allocated to a CCBT group (cCBT;\n                      <jats:italic>n<\/jats:italic>\n                      = 50) or a UC group (usual care;\n                      <jats:italic>n<\/jats:italic>\n                      = 50) by random number table. The State Anxiety Inventory (SAI), Patients Health Questionnaire-9 (PHQ-9), Athens Insomnia Scale (AIS), systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were assessed before intervention (T1), at 1 h before operation (T2), at postoperative 48 h (T3), and 96 h (T4: after intervention completed) respectively. The stress hormone was assayed at T1 and T2. The duration of surgery, anesthesia, and post-anesthesia care unit (PACU) were recorded. A satisfaction survey about nursing services was completed by participants before discharge.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared to the UC group, the SAI scores at T2 and the AIS scores at T3 were lower in the CCBT group (\n                      <jats:italic>p &lt;<\/jats:italic>\n                      0.01 and\n                      <jats:italic>p<\/jats:italic>\n                      = 0.002). The positive rate of participants who were moderate and severe anxiety (SAI score &gt; 37) at T2 were lower (72% vs. 88%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.04); the cortisol levels, SBP, DBP, and HR at T2 in the CCBT group were lower (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.019 and all\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.01); the duration of anesthesia and PACU was shorter (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.001 and\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.01); the CCBT group showed higher satisfaction scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The newly developed cCBT program was an effective non-pharmacological adjunctive treatment for improving the surgery-related psychosomatic responses and perioperative outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>\n                      The study was registered with the Chinese Clinical Trial Registry (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.chictr.org.cn\/listbycreater.aspx\/ChiCTR1900025994\">ChiCTR1900025994<\/jats:ext-link>\n                      ) on 17 September 2019.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13741-021-00195-3","type":"journal-article","created":{"date-parts":[[2021,8,18]],"date-time":"2021-08-18T19:04:03Z","timestamp":1629313443000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The efficacy of computer-assisted cognitive behavioral therapy (cCBT) on psychobiological responses and perioperative outcomes in patients undergoing functional endoscopic sinus surgery: a randomized controlled trial"],"prefix":"10.1186","volume":"10","author":[{"given":"Yang","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuling","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haibin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binquan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,8,19]]},"reference":[{"issue":"8","key":"195_CR1","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/j.biopsych.2008.05.007","volume":"64","author":"J Abelson","year":"2008","unstructured":"Abelson J, Khan S, Liberzon I, Erickson T, Young E. 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The study protocol was conducted with the consent of the Ethics Committee of First Hospital of Shanxi Medical University in China on July 31, 2019 (document number [2019]K-SK028). The informed consents to participate in the study had been obtained from participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"28"}}