{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T17:17:25Z","timestamp":1776100645499,"version":"3.50.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T00:00:00Z","timestamp":1628553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T00:00:00Z","timestamp":1628553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Perioper Med"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Fasting prior to anesthesia is considered aspiration prophylaxis. However, prolonged food and drink restrictions may increase the risk of other complications. The aim of this study was to assess whether a carbohydrate-enriched drink (Nutricia\u2122 preOp\u00ae), recommended by the enhanced recovery after surgery (ERAS) protocol, can improve body hydration in fasting healthy individuals.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Measurements were done with the bioelectric impedance analysis with a Fresenius body composition monitor. Body composition, total body water, water distribution, and hemodynamic parameters were measured at the beginning of the study and after 10\u2009h and 12\u2009h of fasting. Patients fasted for 10\u2009h and then were divided into two groups: the control (<jats:italic>n<\/jats:italic> = 40) and the pre-op group (<jats:italic>n<\/jats:italic> = 41). The pre-op group received 400\u2009mL of Nutricia\u2122 preOp\u00ae, as suggested in the ERAS guidance. The two-tailed Student\u2019s t test was used to compare two groups with normally distributed data and homogenous variances; if variances were heterogeneous, Welch\u2019s test was used. The Mann-Whitney U test was used to compare two groups with non-normal data distribution. <jats:italic>p<\/jats:italic> &lt;\u20090.05 was considered statistically significant.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We found no significant differences between the control and pre-op groups regarding body water distribution and body composition. We did not observe significant losses in the total body water\u00a0after fasting. Also, blood pressure was not affected by fasting.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>We have proven that pre-op did not impact either body composition or body water.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Trial registration<\/jats:title>\n                <jats:p><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>, <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04665349\">NCT04665349<\/jats:ext-link>. Registered on 11 December 2020\u2014retrospectively registered.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s13741-021-00198-0","type":"journal-article","created":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T23:03:56Z","timestamp":1628550236000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The influence of fasting and carbohydrate-enriched drink administration on body water amount and distribution: a volunteer randomized study"],"prefix":"10.1186","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1305-4767","authenticated-orcid":false,"given":"Jakub","family":"Kukli\u0144ski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5353-9849","authenticated-orcid":false,"given":"Karol P.","family":"Steckiewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5887-7436","authenticated-orcid":false,"given":"Bartosz","family":"Seku\u0142a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6073-0588","authenticated-orcid":false,"given":"Aleksander","family":"Aszkie\u0142owicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3441-5162","authenticated-orcid":false,"given":"Rados\u0142aw","family":"Owczuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,8,10]]},"reference":[{"issue":"1","key":"198_CR1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.5114\/ait.2020.93160","volume":"52","author":"M Borys","year":"2020","unstructured":"Borys M, \u017burek S, Kurowicki A, Horeczy B, Bielina B, Sejboth J, et al. 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NKBBN\/126\/2014). The study was performed in accordance with the ethical standards as laid down in 1964 Declaration of Helsinki and its later amendments. All participates gave informed written consent before enrolment in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"27"}}