{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:46:37Z","timestamp":1792273597109,"version":"4.4.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:00:00Z","timestamp":1792195200000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Perioper Med"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Early mobilization is a key component of enhanced recovery after elective colorectal surgery. This pilot trial evaluated the safety and feasibility of an early supervised postoperative exercise intervention in addition to standard care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this single-center randomized controlled pilot trial, 31 patients undergoing elective colorectal surgery were randomized to an intervention group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200916) or control group (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200915). One patient withdrew after randomization, leaving 30 patients for modified intention-to-treat analysis. The intervention consisted of individualized, physiotherapist-supervised exercise sessions on postoperative days 1, 3, and 5. The control group received standard postoperative care according to the institutional ERAS protocol. The originally registered primary endpoint was time to first bowel movement; prior to final analysis, safety and feasibility were designated as the primary outcomes in accordance with the pilot nature of the study. The change was documented transparently. Secondary outcomes included physical performance (Short Physical Performance Battery [SPPB], handgrip strength), time to first bowel movement, patient-reported outcomes, and postoperative complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty patients completed the study (retention 96.8%). Adherence to the intervention was 100%, and no intervention-related adverse events occurred. The intervention group showed significantly better preservation of physical performance, reflected by a more favorable change in SPPB score from baseline to postoperative assessment. No significant between-group differences were observed for time to first bowel movement, handgrip strength, postoperative complications, or other secondary outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Early supervised postoperative exercise after elective colorectal surgery was safe and feasible. Although no differences were found for most secondary outcomes, the intervention improved postoperative physical performance. These exploratory findings warrant confirmation in adequately powered randomized trials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>German Clinical Trials Register, DRKS00036327 (retrospectively registered, 22.04.2025).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s13741-026-00752-8","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:22:17Z","timestamp":1792160537000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early implementation of exercise to facilitate recovery after elective colorectal surgery\u2014a randomized clinical pilot trial"],"prefix":"10.1186","volume":"15","author":[{"given":"Maike","family":"Hermann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Kusma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niki","family":"Taebi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tabea","family":"Kluge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Orth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Moeller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolin","family":"Ecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana","family":"Hetjens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Hardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Reissfelder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Seyfried","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"issue":"5","key":"752_CR1","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","volume":"85","author":"NK Aaronson","year":"1993","unstructured":"Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85(5):365\u201376. https:\/\/doi.org\/10.1093\/jnci\/85.5.365. PMID: 8433390.","journal-title":"J Natl Cancer Inst"},{"issue":"2","key":"752_CR2","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1159\/000537805","volume":"41","author":"EK Abernethy","year":"2024","unstructured":"Abernethy EK, Aly EH. Postoperative ileus after minimally invasive colorectal surgery: a summary of current strategies for prevention and management. Dig Surg. 2024;41(2):79\u201391. https:\/\/doi.org\/10.1159\/000537805. Epub 2024 Feb 15. PMID: 38359801; PMCID: PMC11025667.","journal-title":"Dig Surg"},{"issue":"1","key":"752_CR3","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1097\/SLA.0000000000002293","volume":"267","author":"A Barberan-Garcia","year":"2018","unstructured":"Barberan-Garcia A, Ubr\u00e9 M, Roca J, Lacy AM, Burgos F, Risco R, et al. Personalised prehabilitation in high-risk patients undergoing elective major abdominal surgery: a randomized blinded controlled trial. Ann Surg. 2018;267(1):50\u20136. https:\/\/doi.org\/10.1097\/SLA.0000000000002293. PMID: 28489682.","journal-title":"Ann Surg"},{"issue":"5","key":"752_CR4","doi-asserted-by":"publisher","first-page":"zrae094","DOI":"10.1093\/bjsopen\/zrae094","volume":"8","author":"Z Bayat","year":"2024","unstructured":"Bayat Z, Govindarajan A, Victor JC, Kennedy ED. Impact of structured multicentre enhanced recovery after surgery (ERAS) protocol implementation on length of stay after colorectal surgery. BJS Open. 2024;8(5):zrae094. https:\/\/doi.org\/10.1093\/bjsopen\/zrae094. PMID: 39226376; PMCID: PMC11370790.","journal-title":"BJS Open"},{"issue":"1-2","key":"752_CR5","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1111\/j.0954-6820.1970.tb02901.x","volume":"187","author":"G Borg","year":"1970","unstructured":"Borg G, Linderholm H. Exercise performance and perceived exertion in patients with coronary insufficiency, arterial hypertension and vasoregulatory asthenia. Acta Med Scand. 1970;187(1\u20132):17\u201326. https:\/\/doi.org\/10.1111\/j.0954-6820.1970.tb02901.x. PMID: 5423203.","journal-title":"Acta Med Scand"},{"issue":"2","key":"752_CR6","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1055\/s-0038-1676474","volume":"32","author":"P Cavallaro","year":"2019","unstructured":"Cavallaro P, Bordeianou L. Implementation of an ERAS pathway in colorectal surgery. Clin Colon Rectal Surg. 2019;32(2):102\u20138. https:\/\/doi.org\/10.1055\/s-0038-1676474. Epub 2019 Feb 28. PMID: 30833858; PMCID: PMC6395097.","journal-title":"Clin Colon Rectal Surg"},{"key":"752_CR7","doi-asserted-by":"publisher","unstructured":"Chapman SJ, Thorpe G, Vallance AE, Harji DP, Lee MJ, Fearnhead NS; Association of Coloproctology of Great Britain and Ireland Gastrointestinal Recovery Group. Systematic review of definitions and outcome measures for return of bowel function after gastrointestinal surgery. BJS Open. 2018;3(1):1\u201310. https:\/\/doi.org\/10.1002\/bjs5.102. PMID: 30734010; PMCID: PMC6354191.","DOI":"10.1002\/bjs5.102"},{"issue":"2","key":"752_CR8","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","volume":"240","author":"D Dindo","year":"2004","unstructured":"Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205\u201313. https:\/\/doi.org\/10.1097\/01.sla.0000133083.54934.ae. PMID: 15273542; PMCID: PMC1360123.","journal-title":"Ann Surg"},{"issue":"8","key":"752_CR9","doi-asserted-by":"publisher","first-page":"e90087","DOI":"10.7759\/cureus.90087","volume":"17","author":"MAAE Elnour","year":"2025","unstructured":"Elnour MAAE, Radwan Ahmed RA, Elkhalifa A, ElrayahOmran ME, Osman Hamd MI, Ahmed Aboagla REM. Optimizing postoperative recovery in colorectal surgery: a systematic review on the Efficacy of Enhanced Recovery After Surgery (ERAS) protocols. Cureus. 2025;17(8):e90087. https:\/\/doi.org\/10.7759\/cureus.90087. PMID: 40951154; PMCID: PMC12433266.","journal-title":"Cureus"},{"key":"752_CR10","doi-asserted-by":"publisher","unstructured":"Gaggero P, Fenocchi E, Silva C, L\u00f3pez-Alvarenga JC, Lambert N, Batista F, Sobrino-Cass\u00edo S, White JR, Parra-Blanco A. Identifying the best cutoff value of the fecal occult blood immunochemical test in the detection of advanced and neoplastic colorectal lesions. Cir Cir. 2024. https:\/\/doi.org\/10.24875\/CIRU.23000651. Epub ahead of print. PMID: 38467075.","DOI":"10.24875\/CIRU.23000651"},{"issue":"5","key":"752_CR11","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1097\/ALN.0000000000000393","volume":"121","author":"C Gillis","year":"2014","unstructured":"Gillis C, Li C, Lee L, Awasthi R, Augustin B, Gamsa A, et al. Prehabilita-tion versus rehabilitation: a randomized control trial in patients undergoing colorectal resection for cancer. Anesthesiology. 2014;121(5):937\u201347. https:\/\/doi.org\/10.1097\/ALN.0000000000000393. PMID: 25076007.","journal-title":"Anesthesiology"},{"issue":"2","key":"752_CR12","doi-asserted-by":"publisher","first-page":"M85","DOI":"10.1093\/geronj\/49.2.m85","volume":"49","author":"JM Guralnik","year":"1994","unstructured":"Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49(2):M85-94. https:\/\/doi.org\/10.1093\/geronj\/49.2.m85. PMID: 8126356.","journal-title":"J Gerontol"},{"issue":"3","key":"752_CR13","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1007\/s00268-018-4844-y","volume":"43","author":"UO Gustafsson","year":"2019","unstructured":"Gustafsson UO, Scott MJ, Hubner M, Nygren J, Demartines N, Francis N, et al. Guidelines for perioperative care in elective colorectal surgery: enhanced recovery after surgery (ERAS\u00ae) society recommendations: 2018. World J Surg. 2019;43(3):659\u201395. https:\/\/doi.org\/10.1007\/s00268-018-4844-y. PMID: 30426190.","journal-title":"World J Surg"},{"issue":"5","key":"752_CR14","doi-asserted-by":"publisher","first-page":"922","DOI":"10.3390\/medicina61050922","volume":"61","author":"R Hirani","year":"2025","unstructured":"Hirani R, Podder D, Stala O, Mohebpour R, Tiwari RK, Etienne M. Strategies to reduce hospital length of stay: evidence and challenges. Medicina (Kaunas). 2025;61(5):922. https:\/\/doi.org\/10.3390\/medicina61050922. PMID: 40428880; PMCID: PMC12112870.","journal-title":"Medicina (Kaunas)"},{"issue":"3","key":"752_CR15","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1016\/j.surg.2019.07.032","volume":"167","author":"SK Kamarajah","year":"2020","unstructured":"Kamarajah SK, Bundred J, Weblin J, Tan BHL. Critical appraisal on the impact of preoperative rehabilitation and outcomes after major abdominal and cardiothoracic surgery: a systematic review and meta-analysis. Surgery. 2020;167(3):540\u20139. https:\/\/doi.org\/10.1016\/j.surg.2019.07.032. Epub 2019 Sep 20. PMID: 31548095.","journal-title":"Surgery"},{"issue":"1","key":"752_CR16","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1519\/JPT.0000000000000337","volume":"47","author":"K Kameniar","year":"2024","unstructured":"Kameniar K, Mackintosh S, Van Kessel G, Kumar S. The psychometric properties of the short physical performance battery to assess physical performance in older adults: a systematic review. J Geriatr Phys Ther. 2024;47(1):43\u201354. https:\/\/doi.org\/10.1519\/JPT.0000000000000337. Epub 2022 Apr 19. PMID: 35442231.","journal-title":"J Geriatr Phys Ther"},{"issue":"1-2","key":"752_CR17","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1111\/ans.70426","volume":"96","author":"W Markey","year":"2026","unstructured":"Markey W, Warner R, Blundell J, Mills S. The financial impact of colorectal enhanced recovery after surgery: a single-centre retrospective pre-post cost-analysis. ANZ J Surg. 2026;96(1\u20132):258\u201368. https:\/\/doi.org\/10.1111\/ans.70426. Epub 2025 Dec 19. PMID: 41414972.","journal-title":"ANZ J Surg"},{"issue":"39","key":"752_CR18","doi-asserted-by":"publisher","first-page":"e1934","DOI":"10.1590\/0102-67202026000005e1934","volume":"22","author":"LR Mazzini","year":"2026","unstructured":"Mazzini LR, Leandro-Merhi VA. Reduced handgrip strength and body mass index, gender, and diagnosis are associated with length of stay in hospitalized patients. Arq Bras Cir Dig. 2026;22(39):e1934. https:\/\/doi.org\/10.1590\/0102-67202026000005e1934. PMID: 42339897; PMCID: PMC13286405.","journal-title":"Arq Bras Cir Dig"},{"issue":"1","key":"752_CR19","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1186\/s12876-023-02755-x","volume":"23","author":"J Min","year":"2023","unstructured":"Min J, An KY, Park H, Cho W, Jung HJ, Chu SH, et al. Postoperative inpatient exercise facilitates recovery after laparoscopic surgery in colorectal cancer patients: a randomized controlled trial. BMC Gastroenterol. 2023;23(1):127. https:\/\/doi.org\/10.1186\/s12876-023-02755-x. PMID: 37069526; PMCID: PMC10111844.","journal-title":"BMC Gastroenterol"},{"issue":"8","key":"752_CR20","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1001\/jamasurg.2024.1633","volume":"159","author":"J Min","year":"2024","unstructured":"Min J, Kim JY, Ryu J, Park S, Courneya KS, Ligibel J, et al. Early implementation of exercise to facilitate recovery after breast cancer surgery: a randomized clinical trial. JAMA Surg. 2024;159(8):872\u201380. https:\/\/doi.org\/10.1001\/jamasurg.2024.1633. Erratum in: JAMA Surg. 2024 Aug 1;159(8):960. 10.1001\/jamasurg.2024.2885. PMID: 38837150; PMCID: PMC11154354.","journal-title":"JAMA Surg"},{"issue":"6","key":"752_CR21","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1016\/j.bja.2022.03.009","volume":"128","author":"PS Myles","year":"2022","unstructured":"Myles PS, Shulman MA, Reilly J, Kasza J, Romero L. Measurement of quality of recovery after surgery using the 15-item quality of recovery scale: a systematic review and meta-analysis. Br J Anaesth. 2022;128(6):1029\u201339. https:\/\/doi.org\/10.1016\/j.bja.2022.03.009. Epub 2022 Apr 14. PMID: 35430086.","journal-title":"Br J Anaesth"},{"issue":"1","key":"752_CR22","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/s12893-021-01093-7","volume":"21","author":"Y Namba","year":"2021","unstructured":"Namba Y, Hirata Y, Mukai S, Okimoto S, Fujisaki S, Takahashi M, et al. Clinical indicators for the incidence of postoperative ileus after elective surgery for colorectal cancer. BMC Surg. 2021;21(1):80. https:\/\/doi.org\/10.1186\/s12893-021-01093-7. PMID: 33573636; PMCID: PMC7879517.","journal-title":"BMC Surg"},{"issue":"3","key":"752_CR23","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1097\/SLA.0000000000004901","volume":"275","author":"A Onerup","year":"2022","unstructured":"Onerup A, Andersson J, Angenete E, Bock D, B\u00f6rjesson M, Ehrencrona C, et al. Effect of short-term homebased pre- and postoperative exercise on recovery after colorectal cancer surgery (PHYSSURG-C): a randomized clinical trial. Ann Surg. 2022;275(3):448\u201355. https:\/\/doi.org\/10.1097\/SLA.0000000000004901. PMID: 33843798; PMCID: PMC8820776.","journal-title":"Ann Surg"},{"key":"752_CR24","doi-asserted-by":"publisher","unstructured":"Post S, Vilz T. S3-Leitlinie \u201ePerioperatives Management bei gastrointestinalen Tumoren (POMGAT)\u201c [S3 Guideline \"Perioperative management of gastrointestinal tumors (POMGAT)\"]. Chirurgie (Heidelb). 2023;94(5):468. German. https:\/\/doi.org\/10.1007\/s00104-023-01860-7. PMID: 37133564.","DOI":"10.1007\/s00104-023-01860-7"},{"issue":"12","key":"752_CR25","doi-asserted-by":"publisher","first-page":"7822","DOI":"10.1245\/s10434-024-15593-2","volume":"31","author":"D Steffens","year":"2024","unstructured":"Steffens D, Nott F, Koh C, Jiang W, Hirst N, Cole R, et al. Effectiveness of prehabilitation modalities on postoperative outcomes following colorectal cancer surgery: a systematic review of randomised controlled trials. Ann Surg Oncol. 2024;31(12):7822\u201349. https:\/\/doi.org\/10.1245\/s10434-024-15593-2. Epub 2024 Jun 24. PMID: 38914837; PMCID: PMC11467005.","journal-title":"Ann Surg Oncol"},{"key":"752_CR26","doi-asserted-by":"publisher","unstructured":"Sun W, Zhang J. Comparison of clinical efficacy of different colon anastomosis methods in laparoscopic radical resection of colorectal cancer. Cir Cir. 2024;92(3):314\u2013323. English. https:\/\/doi.org\/10.24875\/CIRU.23000602. PMID: 38862107.","DOI":"10.24875\/CIRU.23000602"},{"key":"752_CR27","doi-asserted-by":"publisher","first-page":"101612","DOI":"10.1016\/j.xjon.2026.101612","volume":"30","author":"T Tantisarasart","year":"2026","unstructured":"Tantisarasart T, Rachapongthai N, Tanasansuttiporn J, Karnjanawanichkul O, Petsakul S, Rattanpittayaporna L, et al. Association of preoperative handgrip strength and postoperative recovery with outcomes in cardiac surgery patients \u226560 years old. JTCVS Open. 2026;30:101612. https:\/\/doi.org\/10.1016\/j.xjon.2026.101612.","journal-title":"JTCVS Open"},{"issue":"8","key":"752_CR28","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1007\/s11605-020-04876-0","volume":"25","author":"CY Teng","year":"2021","unstructured":"Teng CY, Myers S, Kenkre TS, Doney L, Tsang WL, Subramaniam K, et al. Targets for intervention? Preoperative predictors of postoperative ileus after colorectal surgery in an enhanced recovery protocol. J Gastrointest Surg. 2021;25(8):2065\u201375. https:\/\/doi.org\/10.1007\/s11605-020-04876-0. Epub 2020 Nov 17. PMID: 33205308; PMCID: PMC8126638.","journal-title":"J Gastrointest Surg"},{"issue":"1","key":"752_CR29","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1177\/15533506241299888","volume":"32","author":"SL van der Storm","year":"2025","unstructured":"van der Storm SL, Jansen M, Mulder MD, Marsman HA, Consten ECJ, den Boer FC, et al. Improving enhanced recovery after surgery (ERAS): the effect of a patient-centred mobile application and an activity tracker on patient engagement in colorectal surgery. Surg Innov. 2025;32(1):5\u201315. https:\/\/doi.org\/10.1177\/15533506241299888. Epub 2024 Nov 8. PMID: 39514899; PMCID: PMC11736976.","journal-title":"Surg Innov"},{"issue":"5","key":"752_CR30","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1007\/s11605-013-2148-y","volume":"17","author":"R Vather","year":"2013","unstructured":"Vather R, Trivedi S, Bissett I. Defining postoperative ileus: results of a systematic review and global survey. J Gastrointest Surg. 2013;17(5):962\u201372. https:\/\/doi.org\/10.1007\/s11605-013-2148-y. Epub 2013 Feb 2. PMID: 23377782.","journal-title":"J Gastrointest Surg"},{"key":"752_CR31","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/1749-8090-5-67","volume":"5","author":"E Westerdahl","year":"2010","unstructured":"Westerdahl E, M\u00f6ller M. Physiotherapy-supervised mobilization and exercise following cardiac surgery: a national questionnaire survey in Sweden. J Cardiothorac Surg. 2010;5:67. https:\/\/doi.org\/10.1186\/1749-8090-5-67. PMID: 20738852; PMCID: PMC2936289.","journal-title":"J Cardiothorac Surg"},{"issue":"5","key":"752_CR32","doi-asserted-by":"publisher","first-page":"zrad102","DOI":"10.1093\/bjsopen\/zrad102","volume":"7","author":"A Willner","year":"2023","unstructured":"Willner A, Teske C, Hackert T, Welsch T. Effects of early postoperative mobilization following gastrointestinal surgery: systematic review and meta-analysis. BJS Open. 2023;7(5):zrad102. https:\/\/doi.org\/10.1093\/bjsopen\/zrad102. PMID: 37846641; PMCID: PMC10580147.","journal-title":"BJS Open"}],"container-title":["Perioperative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13741-026-00752-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13741-026-00752-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s13741-026-00752-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:01:45Z","timestamp":1792270905000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s13741-026-00752-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,16]]},"references-count":32,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["752"],"URL":"https:\/\/doi.org\/10.1186\/s13741-026-00752-8","relation":{},"ISSN":["2047-0525"],"issn-type":[{"value":"2047-0525","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,16]]},"assertion":[{"value":"29 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 October 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was conducted in accordance with the Declaration of Helsinki, and approved by the Ethics Committee II, University Heidelberg, Germany (protocol code: 2024\u2013642 and date of approval: 27.11.2024). Informed consent was obtained from all subjects involved in the study.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors have read and approved the final manuscript.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"94"}}