{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T01:54:24Z","timestamp":1794016464030,"version":"4.8.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Zhejiang medical and health science and technology plan project","award":["no. 201344330"],"award-info":[{"award-number":["no. 201344330"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Med Res"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To investigate risk factors associated with left ventricular diastolic dysfunction (LVDD) of patients with septic shock.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>Patients with septic shock concomitant with or without LVDD were retrospectively enrolled and divided into the LVDD group (<jats:italic>n<\/jats:italic>\u2009=\u200917) and control without LVDD (<jats:italic>n<\/jats:italic>\u2009=\u200985). The clinical and ultrasound data were analyzed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A significant (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) difference existed between the two groups in serum creatinine, APACHE II score, serum glucose, triglyceride, BUN, FT4, LAVI, mitral E, average e\u2019, E\/average e\u2019, septal e\u2019, septal e\u2019\/septal s\u2019, E\/septal e\u2019, lateral s\u2019, lateral e\u2019, and E\/lateral e\u2019. LAVI\u2009&gt;\u200937\u00a0mL\/m<jats:sup>2<\/jats:sup>, septal e\u2019\u2009&lt;\u20097\u00a0cm\/s (OR 11.04, 95% CI 3.38\u201336.05), septal e\u2019\/septal s\u2019\u2009&lt;\u20090.8 (OR 4.09, 95% CI 1.37\u201312.25), E\/septal e\u2019\u2009&gt;\u200915 (OR 22.86, 95% CI 6.09\u201385.79), lateral e\u2019\u2009&lt;\u20098\u00a0cm\/s (OR 9.16, 95% CI 2.70\u201331.07), E\/lateral e\u2019\u2009&gt;\u200913 (OR 52, 95% CI 11.99- 225.55), lateral s\u2019\u2009&lt;\u200910 (OR 3.36, 95% CI 1.13\u20139.99), average e\u2019\u2009&gt;\u200910, E\/average e\u2019\u2009&gt;\u200910 (OR 9.53, 95% CI 2.49\u201336.46), APACHE II score\u2009&gt;\u200916 (OR 3.33, 95% CI 1.00\u201311.03), SOFA\u2009&gt;\u20095 (or 3.43, 95% CI 1.11\u201310.60), BUN\u2009&gt;\u200912\u00a0mmol\/L (OR 3.37, 95% CI 1.15\u20139.87), serum creatinine\u2009&gt;\u2009146<jats:italic>\u00a0\u03bcmol\/L<\/jats:italic> (OR 5.08, 95% CI 1.69\u201315.23), serum glucose\u2009&gt;\u20098\u00a0mmol\/L (OR 3.36, 95% CI 1.09\u201310.40), and triglyceride\u2009&gt;\u20091.8\u00a0mmol\/L were significant (P\u2009&lt;\u20090.05) risk factors for LVDD. LAVI\u2009&gt;\u200937\u00a0ml\/m<jats:sup>2<\/jats:sup>, lateral e\u2019\u2009&lt;\u20098\u00a0cm\/s, E\/lateral e\u2019\u2009&gt;\u200913, and SOFA\u2009&gt;\u20095 were significant (P\u2009&lt;\u20090.05) independent risk factors for LVDD. ROC curve analysis demonstrated that the cut-off value and AUC were 37.09\u00a0mL\/m<jats:sup>2<\/jats:sup> and 0.85 for LAVI, 8.00\u00a0cm\/s and 0.89 for lateral e\u2019, 12.86 and 0.82 for E\/lateral e\u2019, and 5.00 and 0.69 for SOFA, respectively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Left atrial volume index, mitral lateral e\u2019, E\/lateral e\u2019, and SOFA score are significant independent risk factors for predicting left ventricular diastolic dysfunction in patients with septic shock.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40001-022-00761-5","type":"journal-article","created":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T01:37:36Z","timestamp":1658972256000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Factors associated with left ventricular diastolic dysfunction in patients with septic shock"],"prefix":"10.1186","volume":"27","author":[{"given":"Wei-Dong","family":"Ge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-Zhi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bang-Chuan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding-Yuan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,7,27]]},"reference":[{"key":"761_CR1","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/MCC.0000000000000834","volume":"27","author":"A Daulasim","year":"2021","unstructured":"Daulasim A, Vieillard-Baron A, Geri G. 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