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For primary analysis, multivariate logistic regression model was used to evaluate predictors and a risk score system was devised based on the prediction model. For secondary analysis, a Cox proportion hazard model was performed to assess characteristics associated with the time from TAVR to PPMI. The model was validated internally via bootstrap and externally using an independent cohort.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>48 (14.3%) patients in the derivation set had PPMI after TAVR. Prior right bundle branch block (RBBB, OR: 10.46; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), pre-procedural aortic valve area (AVA, OR: 1.41; <jats:italic>p<\/jats:italic>\u2009=\u20090.004) and post- to pre-procedural AVA ratio (OR: 1.72; <jats:italic>p<\/jats:italic>\u2009=\u20090.043) were identified as independent predictors for PPMI. AUC was 0.7 and 0.71 in the derivation and external validation set. Prior RBBB (HR: 5.07; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), pre-procedural AVA (HR: 1.33; <jats:italic>p<\/jats:italic>\u2009=\u20090.001), post-procedural AVA to prosthetic nominal area ratio (HR: 0.02; <jats:italic>p<\/jats:italic>\u2009=\u20090.039) and post- to pre-procedural troponin-T difference (HR: 1.72; <jats:italic>p<\/jats:italic>\u2009=\u20090.017) are independently associated with time to PPMI.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The post-procedural prediction model achieved high discriminative power and accuracy for PPMI. The risk score system was constructed and validated, providing an accessible tool in clinical setting regarding the Chinese population.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40001-023-01237-w","type":"journal-article","created":{"date-parts":[[2023,7,29]],"date-time":"2023-07-29T18:01:59Z","timestamp":1690653719000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A prediction model for permanent pacemaker implantation after transcatheter aortic valve replacement"],"prefix":"10.1186","volume":"28","author":[{"given":"Yiming","family":"Qi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhi","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuefan","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shasha","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daxin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junbo","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,7,29]]},"reference":[{"issue":"18","key":"1237_CR1","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1056\/NEJMoa1814052","volume":"380","author":"MJ Mack","year":"2019","unstructured":"Mack MJ, Leon MB, Thourani VH, Makkar R, Kodali SK, Russo M, et al. 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The ethics committee approved this study at Zhongshan Hospital, Fudan University (Ethics approval number: B2020-039). Participants provided written informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"262"}}