{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:03:24Z","timestamp":1788314604674,"version":"build-2803163510"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T00:00:00Z","timestamp":1707955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T00:00:00Z","timestamp":1707955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"crossref","award":["ZR2023MH331"],"award-info":[{"award-number":["ZR2023MH331"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Youth Independent Innovation Science Fund of the 960th Hospital of PLA","award":["2023FY03"],"award-info":[{"award-number":["2023FY03"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Med Res"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Assessing the efficacy and safety of Vacuum Sealing Drainage (VSD) in treating deep incision infections (DII) following posterior cervical internal fixation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We retrospectively studied the clinical effects of VSD and Traditional Negative Pressure Drainage (TND) on 12 patients with deep incision infection after posterior cervical fixation surgery who were treated in our department from 2012 to 2020. A comparison of patient-related factors (age, gender, BMI, comorbidities, initial internal fixation surgery segment, preoperative laboratory inflammation indicators) and surgical-related factors (postoperative duration of fever, positive rate of drainage fluid bacterial culture, Visual Analogue Scale (VAS) score at 3\u00a0days after surgery, laboratory indicators at 3\u00a0days after surgery, debridement frequency and drainage time, hospital stay, internal fixation retention rate, and infection recurrence rate) between the VSD group and the TND group was conducted using independent sample <jats:italic>t<\/jats:italic> tests to draw experimental conclusions.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>This study included 12 patients, with six cases of VSD (5 males and 1 female) and six cases of TND (4 males and 2 females). The VSD group had significantly lower postoperative fever time (1.50\u2009\u00b1\u20090.46\u00a0days vs. 4.28\u2009\u00b1\u20090.97\u00a0days, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), a higher positive rate of bacterial cultures in drainage fluid (5\/6 vs. 2\/6, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), lower 3\u00a0day VAS scores (3.13\u2009\u00b1\u20090.83 vs. 3.44\u2009\u00b1\u20090.88, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), lower 3\u00a0day CRP levels (66.89\u2009\u00b1\u200923.65\u00a0mg\/L vs. 57.11\u2009\u00b1\u200918.18\u00a0mg\/L, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), a shorter total drainage time (14.50\u2009\u00b1\u20092.98\u00a0days vs. 22.56\u2009\u00b1\u20093.01\u00a0days, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), and a higher total drainage flow rate (395.63\u2009\u00b1\u200960.97\u00a0ml vs. 155.56\u2009\u00b1\u200932.54\u00a0ml, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) than the TND group (the total drainage volume throughout the entire treatment process). In addition, the frequency of debridement (2.67\u2009\u00b1\u20090.52 times vs. 3.17\u2009\u00b1\u20090.41\u00a0times, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) and average hospital stay (23.13\u2009\u00b1\u20093.27\u00a0days vs. 34.33\u2009\u00b1\u20096.86\u00a0days, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) were significantly lower in the VSD group, although both groups retained internal fixation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>VSD is a secure and effective treatment for deep incision infections that results from cervical posterior internal fixation surgery.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40001-024-01717-7","type":"journal-article","created":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T08:03:09Z","timestamp":1707984189000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Investigating the efficacy of vacuum sealing drainage versus traditional negative pressure drainage in treating deep incision infections following posterior cervical internal fixation\u2014a retrospective cohort study"],"prefix":"10.1186","volume":"29","author":[{"given":"Jianhua","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawei","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengqi","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,15]]},"reference":[{"issue":"10","key":"1717_CR1","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1016\/j.spinee.2019.04.019","volume":"19","author":"JA Youssef","year":"2019","unstructured":"Youssef JA, Heiner AD, Montgomery JR, Tender GC, Lorio MP, Morreale JM, Phillips FM. 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Each author certifies that all investigations were conducted in accordance with ethical principles. The participant involved in the study gave their informed consent and signed an informed consent form.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written consent to publish this article was obtained from study participants. Proof of consent to publish from study participants can be requested at any time.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"125"}}