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Patients were categorized into DVT and non-DVT groups. We conducted detailed demographic, comorbidity, and laboratory analyses using univariate and logistic regression methods. Receiver-operating characteristic (ROC) curves were utilized to establish critical thresholds for predictive variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study revealed a 34.4% DVT rate among 180 patients. Univariate analysis identified significant associations between DVT and older age (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031), elevated white blood cell (WBC) count (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005), prolonged thrombin time (TT) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.030), and increased D-dimer levels (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Logistic regression showed that age (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009, odds ratio [OR]\u2009=\u20091.049), WBC count (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001, OR\u2009=\u20091.131), and D-dimer levels (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.010, OR\u2009=\u20091.190) were independent predictors of DVT. ROC analysis established critical thresholds: age (73\u00a0years), D-dimer (3.3\u00a0ng\/mL), and WBC count (9.5\u2009\u00d7\u200910^9\/\u03bcL).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Age, D-dimer, and WBC levels independently predict DVT in elderly patients with hip fractures and CKD. Precise thresholds facilitate personalized DVT risk assessment, enabling early and targeted interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s40001-025-03409-2","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T14:56:13Z","timestamp":1763736973000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluating preoperative risk factors for deep vein thrombosis in elderly patients with hip fractures and chronic kidney disease: a retrospective study"],"prefix":"10.1186","volume":"30","author":[{"given":"Ruili","family":"Jia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqian","family":"Men","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Ran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubin","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,21]]},"reference":[{"key":"3409_CR1","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1111\/cei.12881","volume":"187","author":"DM Boe","year":"2017","unstructured":"Boe DM, Boule LA, Kovacs EJ. 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There is no need to write informed consent forms from patients, because this is a retrospective study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1153"}}