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For participants younger than 13\u00a0years, a parent or legal guardian provided written informed consented and data about the participant and the child\/adolescents provided assent. Participants 13\u00a0years and older had the option to consent for themselves if they were deemed to have sufficient capacity to provide informed consent and provide self-report data, otherwise consent and data were provided from a parent or legal guardian.Access to Atlantic PATH data and biosamples were approved under application #2018\u2013103.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Participants that enrolled in the Spit for Science study consented to deidentified results being shared in unspecified journal publications.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"RS consults to Knight Therapeutics, AIMH Inc, Kye Pharmaceutics Inc and Otsuka Canada Pharmaceuticals. PDA receives grant funding from Biohaven Pharmaceuticals. All other authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"205"}}