{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T20:30:11Z","timestamp":1774470611647,"version":"3.50.1"},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T00:00:00Z","timestamp":1726617600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the Shanxi Province Graduate Education Innovation Program Project","award":["2023KY369"],"award-info":[{"award-number":["2023KY369"]}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82202078"],"award-info":[{"award-number":["82202078"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82202078"],"award-info":[{"award-number":["82202078"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82030058"],"award-info":[{"award-number":["82030058"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"City-school Science and Technology Strategic Cooperation Projects","award":["22SXQT0351"],"award-info":[{"award-number":["22SXQT0351"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hum Genomics"],"DOI":"10.1186\/s40246-024-00672-y","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T13:50:08Z","timestamp":1726753808000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Genetic history and biological adaptive landscape of the Tujia people inferred from shared haplotypes and alleles"],"prefix":"10.1186","volume":"18","author":[{"given":"Jing","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengge","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhan","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingxin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengyang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuxia","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangping","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuntao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haoran","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiyong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuguo","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhang","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaomeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanglin","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangwei","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,9,18]]},"reference":[{"issue":"6","key":"672_CR1","doi-asserted-by":"publisher","first-page":"2223","DOI":"10.1073\/pnas.1221359110","volume":"110","author":"Q Fu","year":"2013","unstructured":"Fu Q, Meyer M, Gao X, Stenzel U, Burbano HA, Kelso J, Paabo S. DNA analysis of an early modern human from Tianyuan Cave, China. Proc Natl Acad Sci U S A. 2013;110(6):2223\u20137.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"672_CR2","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1038\/jhg.2010.40","volume":"55","author":"H Zhong","year":"2010","unstructured":"Zhong H, Shi H, Qi XB, Xiao CJ, Jin L, Ma RZ, Su B. Global distribution of Y-chromosome haplogroup C reveals the prehistoric migration routes of African exodus and early settlement in East Asia. J Hum Genet. 2010;55(7):428\u201335.","journal-title":"J Hum Genet"},{"key":"672_CR3","doi-asserted-by":"crossref","unstructured":"Li X, Wang M, Su H, Duan S, Sun Y, Chen H, Wang Z, Sun Q, Yang Q, Chen J et al. Evolutionary history and biological adaptation of Han Chinese people on the Mongolian Plateau. hLife 2024.","DOI":"10.1016\/j.hlife.2024.04.005"},{"key":"672_CR4","doi-asserted-by":"crossref","unstructured":"He G, Wang M, Luo L, Sun Q, Yuan H, Lv H, Feng Y, Liu X, Cheng J, Bu F et al. Population genomics of Central Asian peoples unveil ancient Trans-Eurasian genetic admixture and cultural exchanges. hLife 2024.","DOI":"10.1016\/j.hlife.2024.06.006"},{"key":"672_CR5","doi-asserted-by":"crossref","unstructured":"Wang M, Chen H, Luo L, Huang Y, Duan S, Yuan H, Tang R, Liu C, He G. Forensic investigative genetic genealogy: expanding pedigree tracing and genetic inquiry in the genomic era. J Genet Genomics 2024.","DOI":"10.1016\/j.jgg.2024.06.016"},{"issue":"5","key":"672_CR6","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.jgg.2023.10.002","volume":"51","author":"Y Sun","year":"2024","unstructured":"Sun Y, Wang M, Sun Q, Liu Y, Duan S, Wang Z, et al. Distinguished biological adaptation architecture aggravated population differentiation of Tibeto-Burman-speaking people. J Genet Genomics. 2024;51(5):517\u201330.","journal-title":"J Genet Genomics"},{"key":"672_CR7","doi-asserted-by":"crossref","unstructured":"Wang M, Huang Y, Liu K, Wang Z, Zhang M, Yuan H, et al. Multiple human population movements and cultural dispersal events shaped the landscape of Chinese paternal heritage. Mol Biol Evol. 2024;41(7).","DOI":"10.1093\/molbev\/msae122"},{"issue":"7754","key":"672_CR8","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1038\/s41586-019-1153-z","volume":"569","author":"M Zhang","year":"2019","unstructured":"Zhang M, Yan S, Pan W, Jin L. Phylogenetic evidence for Sino-Tibetan origin in northern China in the late neolithic. Nature. 2019;569(7754):112\u20135.","journal-title":"Nature"},{"issue":"1","key":"672_CR9","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/s12915-024-01854-9","volume":"22","author":"Q Sun","year":"2024","unstructured":"Sun Q, Wang M, Lu T, Duan S, Liu Y, Chen J, Wang Z, Sun Y, Li X, Wang S, et al. Differentiated adaptative genetic architecture and language-related demographical history in South China inferred from 619 genomes from 56 populations. BMC Biol. 2024;22(1):55.","journal-title":"BMC Biol"},{"issue":"1","key":"672_CR10","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s12915-024-01828-x","volume":"22","author":"GL He","year":"2024","unstructured":"He GL, Wang PX, Chen J, Liu Y, Sun YT, Hu R, Duan SH, Sun QX, Tang RK, Yang JB, et al. Differentiated genomic footprints suggest isolation and long-distance migration of Hmong-Mien populations. BMC Biol. 2024;22(1):18.","journal-title":"BMC Biol"},{"issue":"1","key":"672_CR11","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s40246-023-00476-6","volume":"17","author":"G He","year":"2023","unstructured":"He G, Wang M, Miao L, Chen J, Zhao J, Sun Q, Duan S, Wang Z, Xu X, Sun Y, et al. Multiple founding paternal lineages inferred from the newly-developed 639-plex Y-SNP panel suggested the complex admixture and migration history of Chinese people. Hum Genomics. 2023;17(1):29.","journal-title":"Hum Genomics"},{"issue":"7850","key":"672_CR12","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1038\/s41586-021-03336-2","volume":"591","author":"CC Wang","year":"2021","unstructured":"Wang CC, Yeh HY, Popov AN, Zhang HQ, Matsumura H, Sirak K, Cheronet O, Kovalev A, Rohland N, Kim AM, et al. Genomic insights into the formation of human populations in East Asia. Nature. 2021;591(7850):413\u20139.","journal-title":"Nature"},{"issue":"1634","key":"672_CR13","doi-asserted-by":"publisher","first-page":"725243","DOI":"10.3389\/fgene.2021.725243","volume":"12","author":"G He","year":"2021","unstructured":"He G, Wang M, Zou X, Chen P, Wang Z, Liu Y, Yao H, Wei LH, Tang R, Wang CC, et al. Peopling history of the Tibetan Plateau and multiple waves of admixture of tibetans inferred from both ancient and modern genome-wide data. Front Genet. 2021;12(1634):725243.","journal-title":"Front Genet"},{"issue":"1","key":"672_CR14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/jse.12670","volume":"59","author":"G He","year":"2021","unstructured":"He G, Li YX, Wang MG, Zou X, Yeh HY, Yang XM, Wang Z, Tang RK, Zhu SM, Guo JX, et al. Fine-scale genetic structure of Tujia and central Han Chinese revealing massive genetic admixture under language borrowing. J Syst Evol. 2021;59(1):1\u201320.","journal-title":"J Syst Evol"},{"issue":"8","key":"672_CR15","doi-asserted-by":"publisher","first-page":"e103772","DOI":"10.1371\/journal.pone.0103772","volume":"9","author":"CC Wang","year":"2014","unstructured":"Wang CC, Wang LX, Shrestha R, Zhang M, Huang XY, Hu K, Jin L, Li H. Genetic structure of Qiangic populations residing in the western Sichuan corridor. PLoS ONE. 2014;9(8):e103772.","journal-title":"PLoS ONE"},{"issue":"6219","key":"672_CR16","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1126\/science.1259172","volume":"347","author":"FH Chen","year":"2015","unstructured":"Chen FH, Dong GH, Zhang DJ, Liu XY, Jia X, An CB, Ma MM, Xie YW, Barton L, Ren XY, et al. Agriculture facilitated permanent human occupation of the Tibetan Plateau after 3600 B.P. Science. 2015;347(6219):248\u201350.","journal-title":"Science"},{"key":"672_CR17","doi-asserted-by":"publisher","first-page":"1066655","DOI":"10.3389\/fgene.2023.1066655","volume":"14","author":"J Lan","year":"2023","unstructured":"Lan J, Zhang X, Cui W, Mei S, Xu J, Zhu B. Genetic polymorphisms and population genetic analyses of 57 autosomal InDel loci in Hubei Tujia group. Front Genet. 2023;14:1066655.","journal-title":"Front Genet"},{"issue":"3","key":"672_CR18","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1007\/s00414-019-02115-z","volume":"134","author":"R Feng","year":"2020","unstructured":"Feng R, Zhao Y, Chen S, Li Q, Fu Y, Zhao L, Zhou Y, Zhang L, Mei X, Shi M, et al. Genetic analysis of 50 Y-STR loci in Dong, Miao, Tujia, and Yao populations from Hunan. Int J Legal Med. 2020;134(3):981\u20133.","journal-title":"Int J Legal Med"},{"issue":"3","key":"672_CR19","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1007\/s00414-020-02287-z","volume":"135","author":"L Zhang","year":"2021","unstructured":"Zhang L, Yang F, Bai X, Yao Y, Li J. Genetic polymorphism analysis of 23 STR loci in the Tujia population from Chongqing, Southwest China. Int J Legal Med. 2021;135(3):761\u20133.","journal-title":"Int J Legal Med"},{"issue":"11","key":"672_CR20","doi-asserted-by":"publisher","first-page":"e1473","DOI":"10.1002\/mgg3.1473","volume":"8","author":"L Luo","year":"2020","unstructured":"Luo L, Gao H, Yao L, Long F, Zhang H, Zhang L, Liu Y, Yu J, Yu L, Chen P. Genetic diversity, forensic feature, and phylogenetic analysis of Guizhou Tujia population via 19 X-STRs. Mol Genet Genomic Med. 2020;8(11):e1473.","journal-title":"Mol Genet Genomic Med"},{"key":"672_CR21","doi-asserted-by":"publisher","first-page":"36842","DOI":"10.1038\/srep36842","volume":"6","author":"C Shen","year":"2016","unstructured":"Shen C, Zhu B, Yao T, Li Z, Zhang Y, Yan J, Wang B, Bie X, Tai F. A 30-InDel assay for Genetic Variation and Population Structure Analysis of Chinese Tujia Group. Sci Rep. 2016;6:36842.","journal-title":"Sci Rep"},{"key":"672_CR22","doi-asserted-by":"crossref","unstructured":"He G, Li Y, Wang M, Zou X, Yeh H, Yang X, et al. Fine-scale genetic structure of Tujia and central Han Chinese revealing massive genetic admixture under language borrowing. J Syst Evol. 2021;59(1):1\u201320.","DOI":"10.1111\/jse.12670"},{"issue":"1","key":"672_CR23","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1111\/jse.12827","volume":"61","author":"GL He","year":"2022","unstructured":"He GL, Wang MG, Zou X, Yeh HY, Liu CH, Liu C, Chen G, Wang CC. Extensive ethnolinguistic diversity at the crossroads of North China and South Siberia reflects multiple sources of genetic diversity. J Syst Evol. 2022;61(1):230\u201350.","journal-title":"J Syst Evol"},{"key":"672_CR24","doi-asserted-by":"publisher","first-page":"4689","DOI":"10.1038\/ncomms5689","volume":"5","author":"M Lipson","year":"2014","unstructured":"Lipson M, Loh PR, Patterson N, Moorjani P, Ko YC, Stoneking M, Berger B, Reich D. Reconstructing austronesian population history in Island Southeast Asia. Nat Commun. 2014;5:4689.","journal-title":"Nat Commun"},{"issue":"3","key":"672_CR25","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.cell.2012.07.009","volume":"150","author":"J Lachance","year":"2012","unstructured":"Lachance J, Vernot B, Elbers CC, Ferwerda B, Froment A, Bodo JM, Lema G, Fu W, Nyambo TB, Rebbeck TR, et al. Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers. Cell. 2012;150(3):457\u201369.","journal-title":"Cell"},{"issue":"7624","key":"672_CR26","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1038\/nature19792","volume":"538","author":"L Pagani","year":"2016","unstructured":"Pagani L, Lawson DJ, Jagoda E, M\u00f6rseburg A, Eriksson A, Mitt M, Clemente F, Hudjashov G, DeGiorgio M, Saag L, et al. Genomic analyses inform on migration events during the peopling of Eurasia. Nature. 2016;538(7624):238\u201342.","journal-title":"Nature"},{"issue":"7624","key":"672_CR27","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1038\/nature18299","volume":"538","author":"AS Malaspinas","year":"2016","unstructured":"Malaspinas AS, Westaway MC, Muller C, Sousa VC, Lao O, Alves I, Bergstr\u00f6m A, Athanasiadis G, Cheng JY, Crawford JE, et al. A genomic history of Aboriginal Australia. Nature. 2016;538(7624):207\u201314.","journal-title":"Nature"},{"issue":"9","key":"672_CR28","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1038\/ng.3621","volume":"48","author":"M Mondal","year":"2016","unstructured":"Mondal M, Casals F, Xu T, Dall\u2019Olio GM, Pybus M, Netea MG, Comas D, Laayouni H, Li Q, Majumder PP, et al. Genomic analysis of Andamanese provides insights into ancient human migration into Asia and adaptation. Nat Genet. 2016;48(9):1066\u201370.","journal-title":"Nat Genet"},{"issue":"1","key":"672_CR29","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1038\/s41597-024-03031-7","volume":"11","author":"S Mallick","year":"2024","unstructured":"Mallick S, Micco A, Mah M, Ringbauer H, Lazaridis I, Olalde I, Patterson N, Reich D. The Allen Ancient DNA resource (AADR) a curated compendium of ancient human genomes. Sci Data. 2024;11(1):182.","journal-title":"Sci Data"},{"key":"672_CR30","doi-asserted-by":"publisher","first-page":"735786","DOI":"10.3389\/fgene.2021.735786","volume":"12","author":"X Yang","year":"2021","unstructured":"Yang X, Sarengaowa, He G, Guo J, Zhu K, Ma H, Zhao J, Yang M, Chen J, Zhang X, et al. Genomic insights into the genetic structure and natural selection of mongolians. Front Genet. 2021;12:735786.","journal-title":"Front Genet"},{"issue":"1","key":"672_CR31","first-page":"59","volume":"171","author":"P Skoglund","year":"2017","unstructured":"Skoglund P, Thompson JC, Prendergast ME, Mittnik A, Sirak K, Hajdinjak M, et al. Reconstructing prehistoric African population structure. Cell. 2017;171(1):59\u201371, e21.","journal-title":"Reconstructing Prehistoric Afr Popul Struct Cell"},{"issue":"1","key":"672_CR32","doi-asserted-by":"publisher","first-page":"3352","DOI":"10.1038\/s41467-024-47735-1","volume":"15","author":"M Andr\u00e9","year":"2024","unstructured":"Andr\u00e9 M, Brucato N, Hudjasov G, Pankratov V, Yermakovich D, Montinaro F, Kreevan R, Kariwiga J, Muke J, Boland A, et al. Positive selection in the genomes of two Papua New Guinean populations at distinct altitude levels. Nat Commun. 2024;15(1):3352.","journal-title":"Nat Commun"},{"issue":"2","key":"672_CR33","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s00439-008-0537-1","volume":"124","author":"A Fujimoto","year":"2008","unstructured":"Fujimoto A, Ohashi J, Nishida N, Miyagawa T, Morishita Y, Tsunoda T, Kimura R, Tokunaga K. A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia. Hum Genet. 2008;124(2):179\u201385.","journal-title":"Hum Genet"},{"issue":"6","key":"672_CR34","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1093\/hmg\/ddm355","volume":"17","author":"A Fujimoto","year":"2008","unstructured":"Fujimoto A, Kimura R, Ohashi J, Omi K, Yuliwulandari R, Batubara L, Mustofa MS, Samakkarn U, Settheetham-Ishida W, Ishida T, et al. A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness. Hum Mol Genet. 2008;17(6):835\u201343.","journal-title":"Hum Mol Genet"},{"issue":"7","key":"672_CR35","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1038\/s41388-021-01902-6","volume":"41","author":"R Williams","year":"2022","unstructured":"Williams R, Jobling S, Sims AH, Mou C, Wilkinson L, Collu GM, Streuli CH, Gilmore AP, Headon DJ, Brennan K. Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia. Oncogene. 2022;41(7):1040\u20139.","journal-title":"Oncogene"},{"issue":"1","key":"672_CR36","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1186\/s12885-020-07485-x","volume":"20","author":"LB Reis","year":"2020","unstructured":"Reis LB, Bakos RM, Vianna FSL, Macedo GS, Jacovas VC, Ribeiro-Dos-Santos AM, Santos S, Bakos L, Ashton-Prolla P. Skin pigmentation polymorphisms associated with increased risk of melanoma in a case-control sample from southern Brazil. BMC Cancer. 2020;20(1):1069.","journal-title":"BMC Cancer"},{"issue":"2","key":"672_CR37","doi-asserted-by":"publisher","first-page":"110","DOI":"10.2174\/138920208784139528","volume":"9","author":"E Giardina","year":"2008","unstructured":"Giardina E, Pietrangeli I, Mart\u00ednez-Labarga C, Martone C, de Angelis F, Spinella A, De Stefano G, Rickards O, Novelli G. Haplotypes in SLC24A5 gene as Ancestry informative markers in different populations. Curr Genom. 2008;9(2):110\u20134.","journal-title":"Curr Genom"},{"issue":"11","key":"672_CR38","doi-asserted-by":"publisher","first-page":"e1003912","DOI":"10.1371\/journal.pgen.1003912","volume":"9","author":"C Basu Mallick","year":"2013","unstructured":"Basu Mallick C, Iliescu FM, Mols M, Hill S, Tamang R, Chaubey G, Goto R, Ho SY, Gallego Romero I, Crivellaro F, et al. The light skin allele of SLC24A5 in South asians and europeans shares identity by descent. PLoS Genet. 2013;9(11):e1003912.","journal-title":"PLoS Genet"},{"key":"672_CR39","doi-asserted-by":"publisher","first-page":"7500","DOI":"10.1038\/ncomms8500","volume":"6","author":"K Adhikari","year":"2015","unstructured":"Adhikari K, Reales G, Smith AJ, Konka E, Palmen J, Quinto-Sanchez M, Acu\u00f1a-Alonzo V, Jaramillo C, Arias W, Fuentes M, et al. A genome-wide association study identifies multiple loci for variation in human ear morphology. Nat Commun. 2015;6:7500.","journal-title":"Nat Commun"},{"key":"672_CR40","doi-asserted-by":"publisher","first-page":"10815","DOI":"10.1038\/ncomms10815","volume":"7","author":"K Adhikari","year":"2016","unstructured":"Adhikari K, Fontanil T, Cal S, Mendoza-Revilla J, Fuentes-Guajardo M, Chacon-Duque JC, Al-Saadi F, Johansson JA, Quinto-Sanchez M, Acuna-Alonzo V, et al. A genome-wide association scan in admixed Latin americans identifies loci influencing facial and scalp hair features. Nat Commun. 2016;7:10815.","journal-title":"Nat Commun"},{"issue":"1","key":"672_CR41","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1038\/s42003-020-01416-z","volume":"3","author":"S Ishida","year":"2020","unstructured":"Ishida S, Kato K, Tanaka M, Odamaki T, Kubo R, Mitsuyama E, Xiao JZ, Yamaguchi R, Uematsu S, Imoto S, et al. Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota. Commun Biol. 2020;3(1):686.","journal-title":"Commun Biol"},{"issue":"7848","key":"672_CR42","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/s41586-020-03065-y","volume":"591","author":"E Pairo-Castineira","year":"2021","unstructured":"Pairo-Castineira E, Clohisey S, Klaric L, Bretherick AD, Rawlik K, Pasko D, Walker S, Parkinson N, Fourman MH, Russell CD, et al. Genetic mechanisms of critical illness in COVID-19. Nature. 2021;591(7848):92\u20138.","journal-title":"Nature"},{"issue":"5","key":"672_CR43","doi-asserted-by":"publisher","first-page":"e1002695","DOI":"10.1371\/journal.pgen.1002695","volume":"8","author":"CS Fox","year":"2012","unstructured":"Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K, Johnson AD, Foster MC, Greenawalt DM, et al. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet. 2012;8(5):e1002695.","journal-title":"PLoS Genet"},{"issue":"2","key":"672_CR44","doi-asserted-by":"publisher","first-page":"398","DOI":"10.3945\/ajcn.114.094557","volume":"101","author":"D Mozaffarian","year":"2015","unstructured":"Mozaffarian D, Kabagambe EK, Johnson CO, Lemaitre RN, Manichaikul A, Sun Q, Foy M, Wang L, Wiener H, Irvin MR, et al. Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. Am J Clin Nutr. 2015;101(2):398\u2013406.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"672_CR45","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1161\/STROKEAHA.117.017430","volume":"49","author":"L Duan","year":"2018","unstructured":"Duan L, Wei L, Tian Y, Zhang Z, Hu P, Wei Q, Liu S, Zhang J, Wang Y, Li D, et al. Novel susceptibility loci for Moyamoya Disease revealed by a genome-wide Association study. Stroke. 2018;49(1):11\u20138.","journal-title":"Stroke"},{"key":"672_CR46","doi-asserted-by":"publisher","first-page":"14357","DOI":"10.1038\/ncomms14357","volume":"8","author":"K Suhre","year":"2017","unstructured":"Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, et al. Connecting genetic risk to disease end points through the human blood plasma proteome. Nat Commun. 2017;8:14357.","journal-title":"Nat Commun"},{"key":"672_CR47","doi-asserted-by":"crossref","unstructured":"Chen J, He G, Ren Z, Wang Q, Liu Y, Zhang H, et al. Genomic Insights Into the Admixture History of Mongolic- and Tungusic-Speaking Populations From Southwestern East Asia. Front Genet. 2021;12:685285.","DOI":"10.3389\/fgene.2021.685285"},{"key":"672_CR48","doi-asserted-by":"publisher","first-page":"815285","DOI":"10.3389\/fgene.2022.815285","volume":"13","author":"J Chen","year":"2022","unstructured":"Chen J, He G, Ren Z, Wang Q, Liu Y, Zhang H, Yang M, Zhang H, Ji J, Zhao J, et al. Fine-Scale Population Admixture Landscape of Tai-Kadai-speaking Maonan in Southwest China inferred from genome-wide SNP data. Front Genet. 2022;13:815285.","journal-title":"Front Genet"},{"issue":"1","key":"672_CR49","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.ajhg.2017.06.005","volume":"101","author":"PM Visscher","year":"2017","unstructured":"Visscher PM, Wray NR, Zhang Q, Sklar P, McCarthy MI, Brown MA, Yang J. 10 years of GWAS Discovery: Biology, function, and translation. Am J Hum Genet. 2017;101(1):5\u201322.","journal-title":"Am J Hum Genet"},{"issue":"7726","key":"672_CR50","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1038\/s41586-018-0579-z","volume":"562","author":"C Bycroft","year":"2018","unstructured":"Bycroft C, Freeman C, Petkova D, Band G, Elliott LT, Sharp K, Motyer A, Vukcevic D, Delaneau O, O\u2019Connell J, et al. The UK Biobank resource with deep phenotyping and genomic data. Nature. 2018;562(7726):203\u20139.","journal-title":"Nature"},{"issue":"D1","key":"672_CR51","doi-asserted-by":"publisher","first-page":"D1005","DOI":"10.1093\/nar\/gky1120","volume":"47","author":"A Buniello","year":"2019","unstructured":"Buniello A, MacArthur JAL, Cerezo M, Harris LW, Hayhurst J, Malangone C, McMahon A, Morales J, Mountjoy E, Sollis E, et al. The NHGRI-EBI GWAS catalog of published genome-wide association studies, targeted arrays and summary statistics 2019. Nucleic Acids Res. 2019;47(D1):D1005\u201312.","journal-title":"Nucleic Acids Res"},{"issue":"1","key":"672_CR52","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1186\/s12915-022-01367-3","volume":"20","author":"Z Yang","year":"2022","unstructured":"Yang Z, Chen H, Lu Y, Gao Y, Sun H, Wang J, Jin L, Chu J, Xu S. Genetic evidence of tri-genealogy hypothesis on the origin of ethnic minorities in Yunnan. BMC Biol. 2022;20(1):166.","journal-title":"BMC Biol"},{"key":"672_CR53","doi-asserted-by":"crossref","unstructured":"Liu C, Yuan B, Wang D, Xu J, Wang M. Genome-wide allele and haplotype-sharing patterns suggested one unique Hmong-Mein-related lineage and biological adaptation history in Southwest China. Hum Genomics. 2023;17(1):3.","DOI":"10.1186\/s40246-023-00477-5"},{"issue":"10","key":"672_CR54","doi-asserted-by":"publisher","first-page":"msac210","DOI":"10.1093\/molbev\/msac210","volume":"39","author":"H Chen","year":"2022","unstructured":"Chen H, Lin R, Lu Y, Zhang R, Gao Y, He YG, Xu SH. Tracing Bai-Yue Ancestry in Aboriginal Li people on Hainan Island. Mol Biol Evol. 2022;39(10):msac210.","journal-title":"Mol Biol Evol"},{"key":"672_CR55","doi-asserted-by":"crossref","unstructured":"Su H, Wang M, Li X, Duan S, Sun Q, Sun Y, et al. Population genetic admixture and evolutionary history in the Shandong Peninsula inferred from integrative modern and ancient genomic resources. BMC Genomics. 2024;25(1):611.","DOI":"10.1186\/s12864-024-10514-9"},{"issue":"5","key":"672_CR56","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1093\/molbev\/msw003","volume":"33","author":"Z Yang","year":"2016","unstructured":"Yang Z, Zhong H, Chen J, Zhang X, Zhang H, Luo X, Xu S, Chen H, Lu D, Han Y, et al. A genetic mechanism for convergent skin lightening during recent human evolution. Mol Biol Evol. 2016;33(5):1177\u201387.","journal-title":"Mol Biol Evol"},{"key":"672_CR57","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s13742-015-0047-8","volume":"4","author":"CC Chang","year":"2015","unstructured":"Chang CC, Chow CC, Tellier LC, Vattikuti S, Purcell SM, Lee JJ. Second-generation PLINK: rising to the challenge of larger and richer datasets. Gigascience. 2015;4:7.","journal-title":"Gigascience"},{"issue":"1","key":"672_CR58","doi-asserted-by":"publisher","first-page":"2700","DOI":"10.1038\/s41467-020-16557-2","volume":"11","author":"C Ning","year":"2020","unstructured":"Ning C, Li T, Wang K, Zhang F, Li T, Wu X, Gao S, Zhang Q, Zhang H, Hudson MJ, et al. Ancient genomes from northern China suggest links between subsistence changes and human migration. Nat Commun. 2020;11(1):2700.","journal-title":"Nat Commun"},{"issue":"3","key":"672_CR59","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1534\/genetics.112.145037","volume":"192","author":"N Patterson","year":"2012","unstructured":"Patterson N, Moorjani P, Luo Y, Mallick S, Rohland N, Zhan Y, Genschoreck T, Webster T, Reich D. Ancient admixture in human history. Genetics. 2012;192(3):1065\u201393.","journal-title":"Genetics"},{"key":"672_CR60","doi-asserted-by":"crossref","unstructured":"Bergstr\u00f6m A, McCarthy SA, Hui R, Almarri MA, Ayub Q, Danecek P, Chen Y, Felkel S, Hallast P, Kamm J et al. Insights into human genetic variation and population history from 929 diverse genomes. Science. 2020;367(6484).","DOI":"10.1126\/science.aay5012"},{"issue":"7855","key":"672_CR61","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1038\/s41586-021-03236-5","volume":"592","author":"J Choin","year":"2021","unstructured":"Choin J, Mendoza-Revilla J, Arauna LR, Cuadros-Espinoza S, Cassar O, Larena M, Ko AM, Harmant C, Laurent R, Verdu P, et al. Genomic insights into population history and biological adaptation in Oceania. Nature. 2021;592(7855):583\u20139.","journal-title":"Nature"},{"issue":"1","key":"672_CR62","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1111\/jse.12826","volume":"61","author":"GL He","year":"2022","unstructured":"He GL, Li YX, Zou X, Yeh HY, Tang RK, Wang PX, Bai JY, Yang XM, Wang Z, Guo JX, et al. Northern gene flow into southeastern East asians inferred from genome-wide array genotyping. J Syst Evol. 2022;61(1):179\u201397.","journal-title":"J Syst Evol"},{"issue":"4","key":"672_CR63","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1111\/jse.12715","volume":"60","author":"GL He","year":"2021","unstructured":"He GL, Wang MG, Li YX, Zou X, Yeh HY, Tang RK, Yang XM, Wang Z, Guo JX, Luo T, et al. Fine-scale north\u2010to\u2010south genetic admixture profile in Shaanxi Han Chinese revealed by genome\u2010wide demographic history reconstruction. J Syst Evol. 2021;60(4):955\u201372.","journal-title":"J Syst Evol"},{"issue":"1","key":"672_CR64","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1111\/jse.12825","volume":"61","author":"MG Wang","year":"2022","unstructured":"Wang MG, He GL, Zou X, Chen PY, Wang Z, Tang RK, Yang XM, Chen J, Yang MQ, Li YX, et al. Reconstructing the genetic admixture history of Tai-Kadai and sinitic people: insights from genome\u2010wide SNP data from South China. J Syst Evol. 2022;61(1):157\u201378.","journal-title":"J Syst Evol"},{"issue":"12","key":"672_CR65","doi-asserted-by":"publisher","first-page":"e190","DOI":"10.1371\/journal.pgen.0020190","volume":"2","author":"N Patterson","year":"2006","unstructured":"Patterson N, Price AL, Reich D. Population structure and eigenanalysis. PLoS Genet. 2006;2(12):e190.","journal-title":"PLoS Genet"},{"issue":"9","key":"672_CR66","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1101\/gr.094052.109","volume":"19","author":"DH Alexander","year":"2009","unstructured":"Alexander DH, Novembre J, Lange K. Fast model-based estimation of ancestry in unrelated individuals. Genome Res. 2009;19(9):1655\u201364.","journal-title":"Genome Res"},{"issue":"6","key":"672_CR67","first-page":"1358","volume":"38","author":"BS Weir","year":"1984","unstructured":"Weir BS, Cockerham CC. Estimating F-Statistics for the analysis of Population structure. Evolution. 1984;38(6):1358\u201370.","journal-title":"Evolution"},{"issue":"11","key":"672_CR68","doi-asserted-by":"publisher","first-page":"e1002967","DOI":"10.1371\/journal.pgen.1002967","volume":"8","author":"JK Pickrell","year":"2012","unstructured":"Pickrell JK, Pritchard JK. Inference of population splits and mixtures from genome-wide allele frequency data. PLoS Genet. 2012;8(11):e1002967.","journal-title":"PLoS Genet"},{"issue":"7","key":"672_CR69","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.1093\/molbev\/msw054","volume":"33","author":"S Kumar","year":"2016","unstructured":"Kumar S, Stecher G, Tamura K. MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for bigger datasets. Mol Biol Evol. 2016;33(7):1870\u20134.","journal-title":"Mol Biol Evol"},{"issue":"2","key":"672_CR70","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.ajhg.2011.01.010","volume":"88","author":"BL Browning","year":"2011","unstructured":"Browning BL, Browning SR. A fast, powerful method for detecting identity by descent. Am J Hum Genet. 2011;88(2):173\u201382.","journal-title":"Am J Hum Genet"},{"issue":"2","key":"672_CR71","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1534\/genetics.113.150029","volume":"194","author":"BL Browning","year":"2013","unstructured":"Browning BL, Browning SR. Improving the accuracy and efficiency of identity-by-descent detection in population data. Genetics. 2013;194(2):459\u201371.","journal-title":"Genetics"},{"issue":"3","key":"672_CR72","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1016\/j.ajhg.2015.07.012","volume":"97","author":"SR Browning","year":"2015","unstructured":"Browning SR, Browning BL. Accurate non-parametric estimation of recent effective Population size from segments of identity by Descent. Am J Hum Genet. 2015;97(3):404\u201318.","journal-title":"Am J Hum Genet"},{"issue":"5987","key":"672_CR73","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1126\/science.1190371","volume":"329","author":"X Yi","year":"2010","unstructured":"Yi X, Liang Y, Huerta-Sanchez E, Jin X, Cuo ZX, Pool JE, Xu X, Jiang H, Vinckenbosch N, Korneliussen TS, et al. Sequencing of 50 human exomes reveals adaptation to high altitude. Science. 2010;329(5987):75\u20138.","journal-title":"Science"},{"issue":"1","key":"672_CR74","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1038\/s41467-019-09234-6","volume":"10","author":"Y Zhou","year":"2019","unstructured":"Zhou Y, Zhou B, Pache L, Chang M, Khodabakhshi AH, Tanaseichuk O, Benner C, Chanda SK. Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. Nat Commun. 2019;10(1):1523.","journal-title":"Nat Commun"}],"container-title":["Human Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40246-024-00672-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40246-024-00672-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40246-024-00672-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T13:54:42Z","timestamp":1726754082000},"score":1,"resource":{"primary":{"URL":"https:\/\/humgenomics.biomedcentral.com\/articles\/10.1186\/s40246-024-00672-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,18]]},"references-count":74,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["672"],"URL":"https:\/\/doi.org\/10.1186\/s40246-024-00672-y","relation":{},"ISSN":["1479-7364"],"issn-type":[{"value":"1479-7364","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,18]]},"assertion":[{"value":"15 April 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Informed consent was obtained from all subjects involved in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The Medical Ethics Committees of West China Hospital of Sichuan University approved this study. This study adhered to the principles of the Helsinki Declaration.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Institutional review board statement"}}],"article-number":"104"}}