{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:05:46Z","timestamp":1791342346798,"version":"4.3.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Poverty"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s40249-016-0119-8","type":"journal-article","created":{"date-parts":[[2016,4,22]],"date-time":"2016-04-22T07:22:21Z","timestamp":1461309741000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Buruli ulcer in Nigeria: results of a pilot case study in three rural districts"],"prefix":"10.1186","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1974-8735","authenticated-orcid":false,"given":"Kingsley N.","family":"Ukwaja","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony O.","family":"Meka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alphonsus","family":"Chukwuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kingsley B.","family":"Asiedu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina L.","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Eddyani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph N.","family":"Chukwu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moses C.","family":"Anyim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles C.","family":"Nwafor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel C.","family":"Oshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson O.","family":"Madichie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngozi","family":"Ekeke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Njoku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentigern","family":"Ntana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,4,22]]},"reference":[{"key":"119_CR1","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1586\/14787210.2014.910113","volume":"12","author":"GKL Huang","year":"2014","unstructured":"Huang GKL, Johnson PD. Epidemiology and management of Buruli ulcer. Expert Rev Anti Infect Ther. 2014;12:855\u201365.","journal-title":"Expert Rev Anti Infect Ther."},{"key":"119_CR2","unstructured":"World Health Organization. Buruli ulcer disease factsheet No 199, May 2015. http:\/\/www.who.int\/mediacentre\/factsheets\/fs199\/en\/index.html (accessed July 9, 2015)."},{"key":"119_CR3","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.3201\/eid1008.030886","volume":"10","author":"M Debacker","year":"2004","unstructured":"Debacker M, Aguiar J, Steunou C, Zinsou C, Meyers WM, Guedenon A, et al. Mycobacterium ulcerans disease (Buruli ulcer) in rural hospital, southern Benin, 1997\u20132001. Emerg Infect Dis. 2004;10:1391\u20138.","journal-title":"Emerg Infect Dis."},{"key":"119_CR4","doi-asserted-by":"crossref","first-page":"e2252","DOI":"10.1371\/journal.pntd.0002252","volume":"7","author":"MW Bratschi","year":"2013","unstructured":"Bratschi MW, Bolz M, Minyem JC, Grize L, Wantong FG, Kerber S, et al. Geographic distribution, age pattern and sites of lesions in a cohort of Buruli ulcer patients from the Mape\u2019 Basin of Cameroon. PLoS Negl Trop Dis. 2013;7:e2252.","journal-title":"PLoS Negl Trop Dis."},{"key":"119_CR5","doi-asserted-by":"crossref","first-page":"e2563","DOI":"10.1371\/journal.pntd.0002563","volume":"7","author":"D Mavinga Phanzu","year":"2013","unstructured":"Mavinga Phanzu D, Suykerbuyk P, Saunderson P, Ngwala Lukanu P, Masamba Minuku JB, Imposo DB, et al. Burden of Mycobacterium ulcerans disease (Buruli ulcer) and the underreporting ratio in the territory of Songololo, Democratic Republic of Congo. PLoS Negl Trop Dis. 2013;7:e2563.","journal-title":"PLoS Negl Trop Dis."},{"key":"119_CR6","doi-asserted-by":"crossref","first-page":"167","DOI":"10.3201\/eid0802.010119","volume":"8","author":"G Amofah","year":"2002","unstructured":"Amofah G, Bonsu F, Tetteh C, Okrah J, Asamoa K, Asiedu K, et al. Buruli Ulcer in Ghana: results of a national case search. Emerg Infect Dis. 2002;8:167\u201370.","journal-title":"Emerg Infect Dis."},{"key":"119_CR7","first-page":"46","volume":"94","author":"JM Kanga","year":"2001","unstructured":"Kanga JM, Kacou ED. Epidemiological aspects of Buruli ulcer in Cote d\u2019Ivoire: results of a national survey. Bull Soc Pathol Exot. 2001;94:46\u201351.","journal-title":"Bull Soc Pathol Exot."},{"key":"119_CR8","doi-asserted-by":"crossref","first-page":"e911","DOI":"10.1371\/journal.pntd.0000911","volume":"4","author":"RW Merritt","year":"2010","unstructured":"Merritt RW, Walker ED, Small PLC, Wallace JR, Johnson PDR, Benbow ME, et al. Ecology and Transmission of Buruli Ulcer Disease: A Systematic Review. PLoS Negl Trop Dis. 2010;4:e911.","journal-title":"PLoS Negl Trop Dis."},{"key":"119_CR9","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.3201\/eid1311.061369","volume":"13","author":"PD Johnson","year":"2007","unstructured":"Johnson PD, Azuolas J, Lavender CJ, Wishart E, Stinear TP, Hayman JA, et al. Mycobacterium ulcerans in mosquitoes captured during outbreak of Buruli ulcer, southeastern Australia. Emerg Infect Dis. 2007;13:1653\u201360.","journal-title":"Emerg Infect Dis."},{"key":"119_CR10","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/0035-9203(67)90139-3","volume":"61","author":"HH Gray","year":"1967","unstructured":"Gray HH, Kingma S, Kok SH. Mycobacterial skin ulcers in Nigeria. Trans R Soc Trop Med Hyg. 1967;61:712\u20134.","journal-title":"Trans R Soc Trop Med Hyg."},{"key":"119_CR11","doi-asserted-by":"crossref","unstructured":"Oluwasanmi JO, Solankee TF, Olurin EO, Itayemi SO, Alabi GO, Lucas AO. Mycobacterium ulcerans (Buruli) skin ulceration in Nigeria. Am J Trop Med Hyg. 1976;25:122\u20138.","DOI":"10.4269\/ajtmh.1976.25.122"},{"key":"119_CR12","doi-asserted-by":"crossref","first-page":"782","DOI":"10.3201\/eid1305.070065","volume":"13","author":"O Chukwuekezie","year":"2007","unstructured":"Chukwuekezie O, Ampadu E, Sopoh G, Dossou A, Tiendrebeogo A, Sadiq L, et al. Buruli ulcer, Nigeria. Emerg Infect Dis. 2007;13:782\u20133.","journal-title":"Emerg Infect Dis."},{"key":"119_CR13","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1128\/AEM.02774-13","volume":"80","author":"K Vandelannoote","year":"2014","unstructured":"Vandelannoote K, Jordaens K, Bomans P, Leirs H, Durnez L, Affolabi D, et al. Insertion sequence element single nucleotide polymorphism typing provides insights into the population structure and evolution of Mycobacterium ulcerans across Africa. Appl Environ Microbiol. 2014;80:1197\u2013209.","journal-title":"Appl Environ Microbiol."},{"key":"119_CR14","doi-asserted-by":"crossref","first-page":"520","DOI":"10.4269\/ajtmh.2004.70.520","volume":"70","author":"J Noeske","year":"2004","unstructured":"Noeske J, Kuaban C, Rondini S, Sorlin P, Ciaffi L, Mbuagbaw J, et al. Buruli ulcer disease in Cameroon rediscovered. Am J Trop Med Hyg. 2004;70:520\u20136.","journal-title":"Am J Trop Med Hyg."},{"key":"119_CR15","doi-asserted-by":"crossref","first-page":"e3443","DOI":"10.1371\/journal.pntd.0003443","volume":"9","author":"E Marion","year":"2015","unstructured":"Marion E, Carolan K, Adeye A, Kempf M, Chauty A, Marsollier L, et al. Buruli Ulcer in South Western Nigeria: a retrospective cohort study of patients treated in Benin. PLoS Negl Trop Dis. 2015;9:e3443.","journal-title":"PLoS Negl Trop Dis."},{"key":"119_CR16","unstructured":"World Health Organization. Incidence, prevalence and mapping of Buruli ulcer. http:\/\/www.who.int\/buruli\/research\/priorities\/healthmapping\/en\/ (accessed September 9, 2015)"},{"key":"119_CR17","volume-title":"2006 Population and Housing Census of the Federal Republic of Nigeria. Priority tables (Volume I)","author":"The National Population Commission","year":"2009","unstructured":"The National Population Commission. 2006 Population and Housing Census of the Federal Republic of Nigeria. Priority tables (Volume I). Abuja: The National Population Commission; 2009."},{"key":"119_CR18","unstructured":"World Health Organization. Laboratory diagnosis of buruli ulcer: a manual for health care providers. Portaels F, ed. WHO\/HTM\/NTD\/IDM\/2014.1, World Health Organization, 2014 Geneva"},{"key":"119_CR19","unstructured":"World Health Organization. Treatment of Mycobacterium ulcerans disease (Buruli ulcer): guidance for health workers, 2012. Available at: www.who.int\/iris\/bitstream\/10665\/77771\/1\/97892 41503402_eng.pdf (Accessed 10 July 2015)."},{"key":"119_CR20","doi-asserted-by":"crossref","first-page":"e466","DOI":"10.1371\/journal.pntd.0000466","volume":"3","author":"K Porten","year":"2009","unstructured":"Porten K, Sailor K, Comte E, Njikap A, Sobry A, Sihom F, et al. Prevalence of Buruli Ulcer in Akonolinga health district, Cameroon: results of a cross sectional survey. PLoS Negl Trop Dis. 2009;3:e466.","journal-title":"PLoS Negl Trop Dis."},{"key":"119_CR21","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/j.1365-3156.2005.01465.x","volume":"10","author":"RC Johnson","year":"2005","unstructured":"Johnson RC, Sopoh GE, Boko M, Zinsou C, Gbovi J, Makoutode M, et al. Distribution of Mycobacterium ulcerans Infection (Buruli Ulcer) in the District of Lalo in Benin. Trop Med Int Health. 2005;10:863\u201371.","journal-title":"Trop Med Int Health."},{"key":"119_CR22","doi-asserted-by":"crossref","first-page":"e422","DOI":"10.1016\/S2214-109X(14)70223-2","volume":"2","author":"QB Vincent","year":"2014","unstructured":"Vincent QB, Ardant MF, Adeye A, Goundote A, Saint-Andr\u00e9 JP, Cottin J, et al. Clinical epidemiology of laboratory-confirmed Buruli ulcer in Benin: a cohort study. Lancet Glob Health. 2014;2:e422\u201330.","journal-title":"Lancet Glob Health"},{"key":"119_CR23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0035-9203(73)90317-9","volume":"67","author":"DJP Barker","year":"1973","unstructured":"Barker DJP. Epidemiology of Mycobacterium ulcerans infection. Trans R Soc Trop Med Hyg. 1973;67:43\u20137.","journal-title":"Trans R Soc Trop Med Hyg."},{"key":"119_CR24","doi-asserted-by":"crossref","first-page":"4029","DOI":"10.1128\/AAC.00175-07","volume":"51","author":"A Chauty","year":"2007","unstructured":"Chauty A, Ardant MF, Adeye A, Euverte H, Gu\u00e9d\u00e9non A, Johnson C, et al. Promising clinical efficacy of streptomycin-rifampin combination for treatment of Buruli ulcer (Mycobacterium ulcerans disease). Antimicrob Agents Chemother. 2007;51:4029\u201335.","journal-title":"Antimicrob Agents Chemother."},{"key":"119_CR25","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1365-3156.2007.01990.x","volume":"13","author":"E Mensah-Quainoo","year":"2008","unstructured":"Mensah-Quainoo E, Yeboah-Manu D, Asebi C, Patafuor F, Ofori-Adjei D, Junghanss T, et al. Diagnostic of Mycobacterium ulcerans infection (Buruli ulcer) at a treatment centre in Ghana: a retrospective analysis of laboratory results of clinically diagnosed cases. Trop Med Int Health. 2008;13:191\u20138.","journal-title":"Trop Med Int Health."},{"key":"119_CR26","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1128\/JCM.41.2.794-797.2003","volume":"41","author":"Y Stienstra","year":"2003","unstructured":"Stienstra Y, van der Werf TS, Guarner J, Raghunathan PL, Spotts Whitney EA, van der Graaf WT, et al. Analysis of an IS2404-based nested PCR for diagnosis of Buruli ulcer disease in regions of Ghana where the disease is endemic. J Clin Microbiol. 2003;41:794\u201397.","journal-title":"J Clin Microbiol."},{"key":"119_CR27","doi-asserted-by":"crossref","first-page":"e736","DOI":"10.1371\/journal.pntd.0000736","volume":"4","author":"K Kibadi","year":"2010","unstructured":"Kibadi K, Boelaert M, Fraga AG, Kayinua M, Longatto-Filho A, Minuku J-B, et al. Response to treatment in a prospective cohort of patients with large ulcerated lesions suspected to be Buruli Ulcer (Mycobacterium ulcerans Disease). PLoS Negl Trop Dis. 2010;4:e736.","journal-title":"PLoS Negl Trop Dis."},{"key":"119_CR28","doi-asserted-by":"crossref","first-page":"e321","DOI":"10.1371\/journal.pntd.0000321","volume":"2","author":"K Peeters Grietens","year":"2008","unstructured":"Peeters Grietens K, Um Boock A, Peeters H, Hausmann-Muela S, Toomer E, Ribera JM. \u201cIt is me who endures but my family that suffers\u201d: social isolation as a consequence of the household cost burden of Buruli Ulcer free of charge hospital treatment. PloS Negl Trop Dis. 2008;2:e321.","journal-title":"PloS Negl Trop Dis."},{"key":"119_CR29","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/S1473-3099(14)70882-5","volume":"14","author":"QB Vincent","year":"2014","unstructured":"Vincent QB, Ardant MF, Marsollier L, Chauty A, Alca\u00efs A, Franco-Beninese Buruli Research Group. HIV infection and Buruli ulcer in Africa. Lancet Infect Dis. 2014;14:796\u20137.","journal-title":"Lancet Infect Dis"}],"container-title":["Infectious Diseases of Poverty"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40249-016-0119-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T19:28:45Z","timestamp":1567798125000},"score":1,"resource":{"primary":{"URL":"http:\/\/idpjournal.biomedcentral.com\/articles\/10.1186\/s40249-016-0119-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,22]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["119"],"URL":"https:\/\/doi.org\/10.1186\/s40249-016-0119-8","relation":{},"ISSN":["2049-9957"],"issn-type":[{"value":"2049-9957","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,22]]},"article-number":"39"}}