{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T03:53:20Z","timestamp":1760586800859,"version":"3.37.3"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (CN)","doi-asserted-by":"publisher","award":["81271826"],"award-info":[{"award-number":["81271826"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Poverty"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s40249-016-0124-y","type":"journal-article","created":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T10:43:05Z","timestamp":1459248185000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Serum cholinesterase: a potential assistant biomarker for hand, foot, and mouth disease caused by enterovirus 71 infection"],"prefix":"10.1186","volume":"5","author":[{"given":"Bang-Ning","family":"Cheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Lian","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bi-Quan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Yan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi-Cheng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,3,29]]},"reference":[{"key":"124_CR1","unstructured":"Offical report of the National health and Family Planning Commission of China. http:\/\/www.nhfpc.gov.cn\/jkj\/s3578\/201402\/26700e8a83c04205913a106545069a11.shtml . Accessed 13 Feb 2014."},{"issue":"11","key":"124_CR2","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S1474-4422(10)70209-X","volume":"9","author":"MH Ooi","year":"2010","unstructured":"Ooi MH, Wong SC, Lewthwaite P, Cardosa MJ, Solomon T. Clinical features, diagnosis, and management of enterovirus 71. Lancet Neurol. 2010;9(11):1097\u2013105.","journal-title":"Lancet Neurol"},{"issue":"11","key":"124_CR3","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S1473-3099(10)70194-8","volume":"10","author":"T Solomon","year":"2010","unstructured":"Solomon T, Lewthwaite P, Perera D, Cardosa MJ, McMinn P, Ooi MH. Virology, epidemiology, pathogenesis, and control of enterovirus 71. Lancet Infect Dis. 2010;10(11):778\u201390.","journal-title":"Lancet Infect Dis"},{"issue":"9","key":"124_CR4","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1007\/s00431-012-1731-7","volume":"171","author":"T Yang","year":"2012","unstructured":"Yang T, Xu G, Dong H, Ye M, He T. A case-control study of risk factors for severe hand-foot-mouth disease among children in Ningbo, China, 2010\u20132011. Eur J Pediatr. 2012;171(9):1359\u201364.","journal-title":"Eur J Pediatr"},{"issue":"13","key":"124_CR5","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1056\/NEJM199909233411302","volume":"341","author":"CC Huang","year":"1999","unstructured":"Huang CC, Liu CC, Chang YC, Chen CY, Wang ST, Yeh TF. Neurologic complications in children with enterovirus 71 infection. N Engl J Med. 1999;341(13):936\u201342.","journal-title":"N Engl J Med"},{"issue":"9191","key":"124_CR6","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1016\/S0140-6736(99)04434-7","volume":"354","author":"LY Chang","year":"1999","unstructured":"Chang LY, Lin TY, Hsu KH, Huang YC, Lin KL, Hsueh C, et al. Clinical features and risk factors of pulmonary oedema after enterovirus-71-related hand, foot, and mouth disease. Lancet. 1999;354(9191):1682\u20136.","journal-title":"Lancet"},{"issue":"1","key":"124_CR7","doi-asserted-by":"crossref","first-page":"e87603","DOI":"10.1371\/journal.pone.0087603","volume":"9","author":"W Li","year":"2014","unstructured":"Li W, Teng G, Tong H, Jiao Y, Zhang T, Chen H, et al. Study on risk factors for severe hand, foot and mouth disease in China. PLoS ONE. 2014;9(1):e87603.","journal-title":"PLoS ONE"},{"issue":"1","key":"124_CR8","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.virusres.2013.07.009","volume":"177","author":"R Wei","year":"2013","unstructured":"Wei R, Xu L, Zhang N, Zhu K, Yang J, Yang C, et al. Elevated antigen-specific Th2 type response is associated with the poor prognosis of hand, foot and mouth disease. Virus Res. 2013;177(1):62\u20135.","journal-title":"Virus Res"},{"issue":"1","key":"124_CR9","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4103\/0973-1482.39601","volume":"4","author":"A Chougule","year":"2008","unstructured":"Chougule A, Hussain S, Agarwal DP. Prognostic and diagnostic value of serum pseudocholinesterase, serum aspartate transaminase, and serum alinine transaminase in malignancies treated by radiotherapy. J Cancer Res Ther. 2008;4(1):21\u20135.","journal-title":"J Cancer Res Ther"},{"issue":"Pt 2","key":"124_CR10","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1099\/jmm.0.035501-0","volume":"61","author":"CB Silva da","year":"2012","unstructured":"da Silva CB, Wolkmer P, Da Silva AS, Paim FC, Tonin AA, Castro VS, et al. Cholinesterases as markers of the inflammatory process in rats infected with Leptospira interrogans serovar Icterohaemorrhagiae. J Med Microbiol. 2012;61(Pt 2):278\u201384.","journal-title":"J Med Microbiol"},{"issue":"24","key":"124_CR11","first-page":"1473","volume":"30","author":"Ministry of Health of the People\u2019s Republic of China","year":"2010","unstructured":"Ministry of Health of the People\u2019s Republic of China. Diagnosis and treatment guideline on hand-foot-mouth disease. Int J Res Mark. 2010;30(24):1473\u20135.","journal-title":"Int J Res Mark"},{"issue":"11","key":"124_CR12","doi-asserted-by":"crossref","first-page":"e1025","DOI":"10.1016\/j.ijid.2013.04.003","volume":"17","author":"SJ He","year":"2013","unstructured":"He SJ, Han JF, Ding XX, Wang YD, Qin CF. Characterization of enterovirus 71 and coxsackievirus A16 isolated in hand, foot, and mouth disease patients in Guangdong, 2010. Int J Infect Dis. 2013;17(11):e1025\u201330.","journal-title":"Int J Infect Dis"},{"issue":"4","key":"124_CR13","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S1473-3099(13)70342-6","volume":"14","author":"W Xing","year":"2014","unstructured":"Xing W, Liao Q, Viboud C, Zhang J, Sun J, Wu JT, et al. Hand, foot, and mouth disease in China, 2008\u201312: an epidemiological study. Lancet Infect Dis. 2014;14(4):308\u201318.","journal-title":"Lancet Infect Dis"},{"issue":"8","key":"124_CR14","doi-asserted-by":"crossref","first-page":"e0135503","DOI":"10.1371\/journal.pone.0135503","volume":"10","author":"B Liu","year":"2015","unstructured":"Liu B, Luo L, Yan S, Wen T, Bai W, Li H, et al. Clinical Features for Mild Hand, Foot and Mouth Disease in China. PLoS ONE. 2015;10(8):e0135503.","journal-title":"PLoS ONE"},{"issue":"13","key":"124_CR15","first-page":"2965","volume":"45","author":"BN Du La","year":"1986","unstructured":"La Du BN, Lockridge O. Molecular biology of human serum cholinesterase. Fed Proc. 1986;45(13):2965\u20139.","journal-title":"Fed Proc"},{"issue":"3","key":"124_CR16","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.coph.2005.01.014","volume":"5","author":"I Silman","year":"2005","unstructured":"Silman I, Sussman JL. Acetylcholinesterase: \u2018classical\u2019 and \u2018non-classical\u2019 functions and pharmacology. Curr Opin Pharmacol. 2005;5(3):293\u2013302.","journal-title":"Curr Opin Pharmacol"},{"issue":"1","key":"124_CR17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s13539-012-0083-5","volume":"4","author":"L Santarpia","year":"2013","unstructured":"Santarpia L, Grandone I, Contaldo F, Pasanisi F. Butyrylcholinesterase as a prognostic marker: a review of the literature. J Cachex Sarcopenia Muscle. 2013;4(1):31\u20139.","journal-title":"J Cachex Sarcopenia Muscle"},{"issue":"5","key":"124_CR18","doi-asserted-by":"crossref","first-page":"429","DOI":"10.3325\/cmj.2013.54.429","volume":"54","author":"L Mikecin","year":"2013","unstructured":"Mikecin L, Krizmaric M, Stepan Giljevic J, Gjurasin M, Kern J, Lenicek Krleza J, et al. Pseudocholinesterase activity in cerebrospinal fluid as a biomarker of solid central nervous system tumors in children. Croat Med J. 2013;54(5):429\u201335.","journal-title":"Croat Med J"},{"key":"124_CR19","doi-asserted-by":"crossref","unstructured":"Sato T, Yamauchi H, Suzuki S, Yoshihisa A, Yamaki T, Sugimoto K, et al. Serum cholinesterase is an important prognostic factor in chronic heart failure. Heart Vessels. 2015; 30(2): 204-210.","DOI":"10.1007\/s00380-014-0469-8"},{"issue":"2","key":"124_CR20","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3892\/br.2013.60","volume":"1","author":"F Meng","year":"2013","unstructured":"Meng F, Yin X, Ma X, Guo XD, Jin B, Li H. Assessment of the value of serum cholinesterase as a liver function test for cirrhotic patients. Biomed Rep. 2013;1(2):265\u20138.","journal-title":"Biomed Rep"},{"issue":"1","key":"124_CR21","doi-asserted-by":"crossref","first-page":"15","DOI":"10.7869\/tg.158","volume":"35","author":"J Ramachandran","year":"2014","unstructured":"Ramachandran J, Sajith KG, Priya S, Dutta AK, Balasubramanian KA. Serum cholinesterase is an excellent biomarker of liver cirrhosis. Trop Gastroenterol. 2014;35(1):15\u201320.","journal-title":"Trop Gastroenterol"},{"issue":"3","key":"124_CR22","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/s12031-013-0176-4","volume":"53","author":"S Shenhar-Tsarfaty","year":"2014","unstructured":"Shenhar-Tsarfaty S, Berliner S, Bornstein NM, Soreq H. Cholinesterases as biomarkers for parasympathetic dysfunction and inflammation-related disease. J Mol Neurosci. 2014;53(3):298\u2013305.","journal-title":"J Mol Neurosci"}],"container-title":["Infectious Diseases of Poverty"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40249-016-0124-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T22:15:06Z","timestamp":1567721706000},"score":1,"resource":{"primary":{"URL":"http:\/\/idpjournal.biomedcentral.com\/articles\/10.1186\/s40249-016-0124-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,29]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["124"],"URL":"https:\/\/doi.org\/10.1186\/s40249-016-0124-y","relation":{},"ISSN":["2049-9957"],"issn-type":[{"type":"electronic","value":"2049-9957"}],"subject":[],"published":{"date-parts":[[2016,3,29]]},"article-number":"27"}}