{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:42:08Z","timestamp":1787020928979,"version":"build-2736575974"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T00:00:00Z","timestamp":1614988800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T00:00:00Z","timestamp":1614988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010909","name":"Young Scientists Fund","doi-asserted-by":"publisher","award":["81601792"],"award-info":[{"award-number":["81601792"]}],"id":[{"id":"10.13039\/501100010909","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010909","name":"Young Scientists Fund","doi-asserted-by":"publisher","award":["81703281"],"award-info":[{"award-number":["81703281"]}],"id":[{"id":"10.13039\/501100010909","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NHC Key Laboratory of Echinococcosis Prevention and Control","award":["2020WZK2008"],"award-info":[{"award-number":["2020WZK2008"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Poverty"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Echinococcosis is highly endemic in western and northern China. Tibet Autonomous Region (TAR) is the most serious prevalent area. Linzhi is located in southeastern part of TAR. Dogs are the primary infection source for the transmission of echinococcosis to humans. A control and prevention campaign based on dog management has been implemented in the past three years. This study aims to evaluate the effects of dog management on the infection rate of dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data of dog population, registration and de-worming of seven counties\/district in Linzhi between 2017 and 2019 were obtained from the annual prevention and control report. Domestic dog fecal samples were collected from each endemic town of seven counties\/district in Linzhi in 2019 to determine the infection of domestic dogs using coproantigen enzyme-linked immunosorbent assay (ELISA). Data analysis was processed using SPSS statistics to compare dog infection rate between 2016 and 2019 by chi-square test, and maps were mapped using ArcGIS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In Linzhi, domestic dog population has decreased from 17\u00a0407 in 2017 to 12\u00a0663 in 2019, while the registration rate has increased from 75.9% in 2017 to 98.6% in 2019. Similarly, stray dog population has decreased from 14 336 in 2017 to 11\u00a0837 in 2019, while sheltered rate has increased from 84.6% in 2017 to 96.6% in 2019. Dog de-worming frequency has increased from 4 times per annum in 2017 to 12 times in 2019, indicating that approximately every dog was dewormed monthly. A total of 2715 dog fecal samples were collected for coproantigen ELISA assay. The dog infection rate was 2.8% (77\/2715) in 2019, which was significantly lower than 7.3% (45\/618) in 2016 (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Increased dog registration, decreased dog population, and increased dog de-worming frequency contributed to significantly decrease the dog infection rate in Linzhi. Control and prevention campaign based on dog management could significantly decrease dog infection with\n                      <jats:italic>Echinococcus<\/jats:italic>\n                      spp. in echinococcosis endemic areas.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s40249-021-00805-8","type":"journal-article","created":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T07:03:08Z","timestamp":1615014188000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of management of infection source of echinococcosis in Linzhi, Tibet Autonomous Region of China"],"prefix":"10.1186","volume":"10","author":[{"given":"Ying","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing-Cheng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2692-2770","authenticated-orcid":false,"given":"Li-Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gongsang","family":"Quzhen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Sheng","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,6]]},"reference":[{"key":"805_CR1","doi-asserted-by":"publisher","first-page":"e00075","DOI":"10.1128\/CMR.00075-18","volume":"32","author":"H Wen","year":"2019","unstructured":"Wen H, Vuitton L, Tuxun T, Li J, Vuitton DA, Zhang W, et al. Echinococcosis: advances in the 21st century. Clin Microbiol Rev. 2019;32:e00075-e118.","journal-title":"Clin Microbiol Rev"},{"key":"805_CR2","doi-asserted-by":"publisher","first-page":"e3866","DOI":"10.1136\/bmj.e3866","volume":"344","author":"DP McManus","year":"2012","unstructured":"McManus DP, Gray DJ, Zhang W, Yang Y. Diagnosis, treatment, and management of echinococcosis. BMJ. 2012;344:e3866.","journal-title":"BMJ"},{"key":"805_CR3","volume-title":"Epidemiological survey on echinococcosis in China","author":"GQ Wang","year":"2016","unstructured":"Wang GQ. Epidemiological survey on echinococcosis in China. Shanghai: Shanghai Science and Technology Press; 2016."},{"issue":"1","key":"805_CR4","first-page":"1","volume":"36","author":"WP Wu","year":"2018","unstructured":"Wu WP, Wang H, Wang Q, Zhou XN, Wang LY, Zheng CJ, et al. A nationwide sampling survey on echinococcosis in China during 2012\u20132016. Chin J Parasitol Parasit Dis. 2018;36(1):1\u201314 (in Chinese).","journal-title":"Chin J Parasitol Parasit Dis"},{"key":"805_CR5","unstructured":"Ministry of Health of the People\u2019s Republic of China. Echinococcosis Prevention Action Plan (2010\u20132015). 2010. http:\/\/www.gov.cn\/zwgk\/2010-12\/14\/content_1765485.htm. Accessed 24 Dec 2010 (in Chinese)."},{"key":"805_CR6","unstructured":"National Health and Family Planning Commission of the People\u2019s Republic of China. National plan for echinococcosis and other key parasitic diseases prevention (2016\u20132020). 2016. http:\/\/www.nhc.gov.cn\/jkfpwlz\/zcwj1g\/201902\/a999e19bfae94d3ea68da8be5add58b5.shtml. Accessed 24 Oct 2016 (in Chinese)."},{"issue":"1","key":"805_CR7","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s40249-019-0537-5","volume":"8","author":"B Li","year":"2019","unstructured":"Li B, Quzhen G, Xue CZ, Han S, Chen WQ, Yan XL, et al. 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