{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:43:21Z","timestamp":1757706201448},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T00:00:00Z","timestamp":1623456000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T00:00:00Z","timestamp":1623456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"National Science and Technology Major Project on Important Infectious Diseases Prevention and Control","award":["2018ZX10734-404"],"award-info":[{"award-number":["2018ZX10734-404"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Infect Dis Poverty"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Many valuable and productive patented technologies have been developed to control schistosomiasis in China in the past 70\u00a0years. We conducted a research to analyse patented technologies for schistosomiasis control and prevention filed by Chinese applicants for determining the future patent layout.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The patent databases of China National Intellectual Property Administration and Baiten were comprehensively searched, and patented technologies for schistosomiasis control and prevention, published between January 1950 and December 2020 filed by Chinese applicants were sorted on 30 December 2020. The patent types, technical fields, and patent development trends were analysed using patent indexing.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>There are 184 valid schistosomiasis control technology patents, among them 128 invention patents. The patents related to schistosomiasis control and prevention technology have gone through the germination, growth, and maturity stages. These phases correspond with three phases in schistosomiasis control in China. The main technical aspects were fundamental research (<jats:italic>n<\/jats:italic>\u2009=\u200937), detection (<jats:italic>n<\/jats:italic>\u2009=\u200913), chemotherapy (<jats:italic>n<\/jats:italic>\u2009=\u200961), and armamentarium\/devices (<jats:italic>n<\/jats:italic>\u2009=\u200973), of which the number of patents for detection for diagnosis was smaller. The top three specialised technical fields for patents subgroups, focusing on antiparasitic agents, DNA or RNA, vectors and medicines, of which schistosomicides are the major dominant subgroup.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>We recommend that technologies to be patented for schistosomiasis control and prevention be focused on detection, preliminary studies for molecular detection methods should be significantly enhanced, and patent layout must be performed, which will, in turn, promote accuracy of early diagnosis, not only in humans but also in livestock. It is necessary to develop more anti-schistosomal drugs safely and effectively, exceptionally eco-friendly molluscicides and herbal extracts\u00a0anti-schistosomes, improve treatment, develop vaccines for use in humans.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphic abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1186\/s40249-021-00869-6","type":"journal-article","created":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T12:03:35Z","timestamp":1623499415000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Patented technologies for schistosomiasis control and prevention filed by Chinese applicants"],"prefix":"10.1186","volume":"10","author":[{"given":"Yan-Hong","family":"Xiong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue-Nian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,6,12]]},"reference":[{"key":"869_CR1","unstructured":"Wu GL. Human Parasitology. 4th edition. Beijing: People's Medical Publishing House. 2013: 277\u2013333 (in Chinese)."},{"key":"869_CR2","unstructured":"Schistosomiasis. http:\/\/www.who.int\/mediacentre\/factsheets\/fs115\/en\/index.html. Accessed 21 Jan 2021."},{"issue":"9936","key":"869_CR3","doi-asserted-by":"publisher","first-page":"2253","DOI":"10.1016\/S0140-6736(13)61949-2","volume":"383","author":"DG Colley","year":"2014","unstructured":"Colley DG, Bustinduy AL, Secor WE, King CH. Human schistosomiasis. Lancet. 2014;383(9936):2253\u201364.","journal-title":"Lancet"},{"issue":"50","key":"869_CR4","first-page":"629","volume":"95","author":"World Health Organization","year":"2020","unstructured":"World Health Organization. Schistosomiasis and soil-transmitted helminthiases: numbers of people treated in 2019. Weekly Epidemiol Record. 2020;95(50):629\u201340.","journal-title":"Weekly Epidemiol Record"},{"key":"869_CR5","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/S0065-308X(10)72006-6","volume":"72","author":"XN Zhou","year":"2010","unstructured":"Zhou XN, Bergquist R, Leonardo L, Yang GJ, Yang K, Sudomo M, et al. Schistosomiasis japonica control and research needs. Adv Parasitol. 2010;72:145\u201378.","journal-title":"Adv Parasitol"},{"issue":"1","key":"869_CR6","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/2049-9957-1-8","volume":"1","author":"C Collins","year":"2012","unstructured":"Collins C, Xu J, Tang S. Schistosomiasis control and the health system in P. R. China. Infect Dis Poverty. 2012;1(1):8.","journal-title":"Infect Dis Poverty."},{"issue":"9541","key":"869_CR7","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1016\/S0140-6736(06)69440-3","volume":"368","author":"B Gryseels","year":"2006","unstructured":"Gryseels B, Polman K, Clerinx J, Kestens L. Human schistosomiasis. Lancet. 2006;368(9541):1106\u201318.","journal-title":"Lancet."},{"issue":"1","key":"869_CR8","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S0001-706X(00)00122-4","volume":"77","author":"L Chitsulo","year":"2000","unstructured":"Chitsulo L, Engels D, Montresor A, Savioli L. The global status of schistosomiasis and its control. Acta Trop. 2000;77(1):41\u201351.","journal-title":"Acta Trop."},{"issue":"6","key":"869_CR9","first-page":"551","volume":"32","author":"LJ Zhang","year":"2020","unstructured":"Zhang LJ, Xu ZM, Dang H, Li YL, Lv S, Xu J, et al. Endemic status of schistosomiasis in People\u2019s Republic of China in 2019. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2020;32(6):551\u20138 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"1","key":"869_CR10","first-page":"1","volume":"33","author":"J Xu","year":"2021","unstructured":"Xu J, Hu W, Yang K, Lv S, Li SZ, Zhou XN. Key points and research priorities of schistosomiasis control in China during the 14th Five-Year Plan Period. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2021;33(1):1\u20136 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"1","key":"869_CR11","first-page":"1","volume":"31","author":"SZ Li","year":"2019","unstructured":"Li SZ, Xu J, Wang TP, Wen LY, Yang K, Wang W, et al. Upholding Chinese spirit on schistosomiasis control in the new era to accelerate the progress toward elimination in China. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2019;31(1):1\u201313 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"1","key":"869_CR12","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1186\/s40249-019-0599-4","volume":"8","author":"MB Qian","year":"2019","unstructured":"Qian MB, Chen J, Bergquist R, Li ZJ, Li SZ, Xiao N, et al. Neglected tropical diseases in the People\u2019s Republic of China: progress towards elimination. Infect Dis Poverty. 2019;8(1):86.","journal-title":"Infect Dis Poverty"},{"issue":"1","key":"869_CR13","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/s40249-020-00676-5","volume":"9","author":"J Xu","year":"2020","unstructured":"Xu J, Li SZ, Zhang LJ, Bergquist R, Dang H, Wang Q, et al. Surveillance-based evidence: elimination of schistosomiasis as a public health problem in the Peoples\u2019 Republic of China. Infect Dis Poverty. 2020;9(1):63.","journal-title":"Infect Dis Poverty"},{"issue":"6","key":"869_CR14","first-page":"605","volume":"30","author":"J Xu","year":"2018","unstructured":"Xu J, Lv S, Cao CL, Zhou XN. Progress and challenges of schistosomiasis elimination in China. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2018;30(6):605\u20139 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"1","key":"869_CR15","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1186\/s40249-017-0370-7","volume":"6","author":"R Bergquist","year":"2017","unstructured":"Bergquist R, Zhou XN, Rollinson D, Reinhard-Rupp J, Klohe K. Elimination of schistosomiasis: the tools required. Infect Dis Poverty. 2017;6(1):158.","journal-title":"Infect Dis Poverty"},{"issue":"1","key":"869_CR16","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/s40249-017-0271-9","volume":"6","author":"LP Sun","year":"2017","unstructured":"Sun LP, Wang W, Hong QB, Li SZ, Liang YS, Yang HT, et al. Approaches being used in the national schistosomiasis elimination programme in China: a review. Infect Dis Poverty. 2017;6(1):55.","journal-title":"Infect Dis Poverty"},{"issue":"12","key":"869_CR17","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1111\/j.1365-3156.2009.02403.x","volume":"14","author":"LD Wang","year":"2009","unstructured":"Wang LD, Guo JG, Wu XH, Chen HG, Wang TP, Zhu SP, et al. China\u2019s new strategy to block Schistosoma japonicum transmission: experiences and impact beyond schistosomiasis. Trop Med Int Health. 2009;14(12):1475\u201383.","journal-title":"Trop Med Int Health"},{"issue":"10","key":"869_CR18","doi-asserted-by":"publisher","first-page":"e1372","DOI":"10.1371\/journal.pntd.0001372","volume":"5","author":"EY Seto","year":"2011","unstructured":"Seto EY, Remais JV, Carlton EJ, Wang S, Liang S, Brindley PJ, et al. Toward sustainable and comprehensive control of schistosomiasis in China: lessons from Sichuan. PLoS Negl Trop Dis. 2011;5(10):e1372.","journal-title":"PLoS Negl Trop Dis."},{"issue":"Pt B","key":"869_CR19","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.actatropica.2014.01.006","volume":"141","author":"QB Tong","year":"2015","unstructured":"Tong QB, Chen R, Zhang Y, Yang GJ, Kumagai T, Furushima-Shimogawara R, et al. A new surveillance and response tool: risk map of infected Oncomelania hupensis detected by loop-mediated isothermal amplification (LAMP) from pooled samples. Acta Trop. 2015;141(Pt B):170\u20137.","journal-title":"Acta Trop"},{"issue":"7","key":"869_CR20","first-page":"595","volume":"20","author":"W Wang","year":"2020","unstructured":"Wang W, Yang K. Implementation of precision control to facilitate the progress towards schistosomiasis elimination in China. Chin Trop Med. 2020;20(7):595\u20138 (in Chinese).","journal-title":"Chin Trop Med"},{"issue":"6","key":"869_CR21","first-page":"573","volume":"31","author":"XN Zhou","year":"2019","unstructured":"Zhou XN. A high-quality driver to accelerate the progress towards schistosomiasis elimination by science and technology-led innovation in Jiangsu Province. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2019;31(6):573\u20135 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"key":"869_CR22","unstructured":"The Central Committee of the Communist Party of China, The State Council of the People's Republic of China. 'Healthy China 2030 planning outline'. 2016. http:\/\/www.gov.cn\/xinwen\/2016-10\/25\/content_5124174.htm."},{"issue":"1","key":"869_CR23","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1186\/2041-1480-4-S1-S3","volume":"4","author":"D Eisinger","year":"2013","unstructured":"Eisinger D, Tsatsaronis G, Bundschus M, Wieneke U, Schroeder M. Automated patent categorization and guided patent search using IPC as inspired by MeSH and PubMed. J Biomed Semantics. 2013;4(1):S3.","journal-title":"J Biomed Semantics."},{"issue":"1","key":"869_CR24","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1186\/s12992-017-0306-9","volume":"13","author":"FT Akinsolu","year":"2017","unstructured":"Akinsolu FT, Paiva VN, Souza SS, Varga O. Patent landscape of neglected tropical diseases: an analysis of worldwide patent families. Global Health. 2017;13(1):82.","journal-title":"Global Health."},{"key":"869_CR25","unstructured":"International Patent Classification. http:\/\/www.wipo.int\/classifications\/ipc\/en."},{"key":"869_CR26","doi-asserted-by":"crossref","unstructured":"Harris CG, Arens R, Srinivasan P. Comparison of IPC and USPC classification systems in patent prior art searches. In: Proceedings of the 3rd international workshop on Patent Information Retrieval. ACM, 2010, 27\u201332.","DOI":"10.1145\/1871888.1871894"},{"key":"869_CR27","first-page":"621","volume":"06","author":"YH Xiong","year":"2018","unstructured":"Xiong YH, Zheng B, Xu XN. A study on trends in the development of techniques to prevent and control parasitic diseases based on a patent analysis. Chin J Pathogen Biol. 2018;13(6):621\u20134 (in Chinese).","journal-title":"Chin J Pathogen Biol"},{"key":"869_CR28","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1186\/1756-3305-7-408","volume":"7","author":"W Wang","year":"2014","unstructured":"Wang W, Dai JR, Liang YS. Apropos: factors impacting on progress towards elimination of transmission of schistosomiasis japonica in China. Parasit Vectors. 2014;7:408.","journal-title":"Parasit Vectors"},{"issue":"2","key":"869_CR29","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1056\/NEJMoa0800135","volume":"360","author":"LD Wang","year":"2009","unstructured":"Wang LD, Chen HG, Guo JG, Zeng XJ, Hong XL, Xiong JJ, et al. A strategy to control transmission of Schistosoma japonicum in China. N Engl J Med. 2009;360(2):121\u20138.","journal-title":"N Engl J Med"},{"issue":"3","key":"869_CR30","first-page":"154","volume":"41","author":"LT Lu","year":"2014","unstructured":"Lu LT, Zhu R, Zhang LJ, Guo JG. Bibliometric study on the evolution of schistosomiasis control strategies in China. Int J Med Parasit Dis. 2014;41(3):154\u20138 (in Chinese).","journal-title":"Int J Med Parasit Dis"},{"issue":"4","key":"869_CR31","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1111\/jtm.12031","volume":"20","author":"PL Lim","year":"2013","unstructured":"Lim PL. Schistosoma haematobium in China, ex-Africa: new populations at risk? J Travel Med. 2013;20(4):211\u20133.","journal-title":"J Travel Med"},{"issue":"1","key":"869_CR32","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1186\/1756-3305-6-260","volume":"6","author":"HY Hua","year":"2013","unstructured":"Hua HY, Wang W, Cao GQ, Tang F, Liang YS. Improving the management of imported schistosomiasis haematobia in China: lessons from a case with multiple misdiagnoses. Parasit Vectors. 2013;6(1):260.","journal-title":"Parasit Vectors"},{"issue":"1","key":"869_CR33","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1186\/1756-3305-6-249","volume":"6","author":"W Wang","year":"2013","unstructured":"Wang W, Liang YS, Hong QB, Dai JR. African schistosomiasis in mainland China: risk of transmission and countermeasures to tackle the risk. Parasit Vectors. 2013;6(1):249.","journal-title":"Parasit Vectors"},{"issue":"6","key":"869_CR34","first-page":"591","volume":"31","author":"XN Zhou","year":"2019","unstructured":"Zhou XN, Li SZ, Xu J, Chen JX, Wen LY, Zhang RL, et al. Surveillance and control strategy of imported schistosomiasis mansoni: an expert consensus. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2019;31(6):591\u20135 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"1","key":"869_CR35","first-page":"26","volume":"31","author":"JF Zhang","year":"2019","unstructured":"Zhang JF, Wen LY, Xu J, Liang YS, Yan XL, Ren GH, et al. Current status and transmission risks of oversea imported schistosomiasis in China. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2019;31(1):26\u201332 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"2","key":"869_CR36","first-page":"111","volume":"26","author":"R Zhu","year":"2014","unstructured":"Zhu R, Xu J. Epidemic situation of oversea imported schistosomiasis in China and thinking about its prevention and control. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2014;26(2):111\u20134 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"3","key":"869_CR37","first-page":"221","volume":"25","author":"YS Liang","year":"2013","unstructured":"Liang YS, Wang W, Hong QB, Dai JR. Risk assessment and control measures for import of African schistosomiasis into China. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2013;25(3):221\u20135 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"4","key":"869_CR38","first-page":"273","volume":"17","author":"HQ Zhu","year":"2005","unstructured":"Zhu HQ, Cao CL, Gao FH, Guo JG, Bao ZP, Wang XH, et al. Evaluation of effectiveness of modified Kato-Katz technique for diagnosis of schistosomiasis japonica. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2005;17(4):273\u20137 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"5","key":"869_CR39","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1007\/s00436-010-1970-3","volume":"107","author":"H Zhu","year":"2010","unstructured":"Zhu H, Yu C, Xia X, Dong G, Tang J, Fang L, et al. Assessing the diagnostic accuracy of immunodiagnostic techniques in the diagnosis of schistosomiasis japonica: a meta-analysis. Parasitol Res. 2010;107(5):1067\u201373.","journal-title":"Parasitol Res"},{"issue":"2","key":"869_CR40","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/S0001-706X(02)00010-4","volume":"82","author":"GL Wu","year":"2002","unstructured":"Wu GL. A historical perspective on the immunodiagnosis of schistosomiasis in China. Acta Trop. 2002;82(2):193\u20138.","journal-title":"Acta Trop"},{"key":"869_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/bs.apar.2016.02.001","volume":"92","author":"J Xu","year":"2016","unstructured":"Xu J, Steinman P, Maybe D, Zhou XN, Lv S, Li SZ, et al. Evolution of the National Schistosomiasis Control Programmes in the People\u2019s Republic of China. Adv Parasitol. 2016;92:1\u201338.","journal-title":"Adv Parasitol"},{"key":"869_CR42","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/bs.apar.2016.03.003","volume":"92","author":"LJ Zhang","year":"2016","unstructured":"Zhang LJ, Li SZ, Wen LY, Lin DD, Abe EM, Zhu R, et al. The establishment and function of schistosomiasis surveillance system towards elimination in the People\u2019s Republic of China. Adv Parasitol. 2016;92:117\u201341.","journal-title":"Adv Parasitol"},{"issue":"1","key":"869_CR43","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1186\/s40249-017-0286-2","volume":"6","author":"R Bergquist","year":"2017","unstructured":"Bergquist R, Utzinger J, Keiser J. Controlling schistosomiasis with praziquantel: How much longer without a viable alternative? Infect Dis Poverty. 2017;6(1):74.","journal-title":"Infect Dis Poverty"},{"key":"869_CR44","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/1742-7622-5-19","volume":"5","author":"Q Liu","year":"2008","unstructured":"Liu Q, Tian LG, Xiao SH, Qi Z, Steinmann P, Mak TK, et al. Harnessing the wealth of Chinese scientific literature: schistosomiasis research and control in China. Emerg Themes Epidemiol. 2008;5:19.","journal-title":"Emerg Themes Epidemiol"},{"issue":"1","key":"869_CR45","first-page":"43","volume":"83","author":"XY Chen","year":"2005","unstructured":"Chen XY, Wang LY, Cai JM, Zhou XN, Zheng J, Guo JG, et al. Schistosomiasis control in China: the impact of a 10-year World Bank Loan Project (1992\u20132001). Bull World Health Organ. 2005;83(1):43\u20138.","journal-title":"Bull World Health Organ"},{"issue":"1","key":"869_CR46","first-page":"1","volume":"28","author":"XN Zhou","year":"2016","unstructured":"Zhou XN. Implementation of precision control to achieve the goal of schistosomiasis elimination in China. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2016;28(1):1\u20134 (in Chinese).","journal-title":"Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi"},{"issue":"2\u20133","key":"869_CR47","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.actatropica.2005.07.005","volume":"96","author":"XN Zhou","year":"2005","unstructured":"Zhou XN, Wang LY, Chen MG, Wu XH, Jiang QW, Chen XY, et al. The public health significance and control of schistosomiasis in China\u2013then and now. Acta Trop. 2005;96(2\u20133):97\u2013105.","journal-title":"Acta Trop"},{"issue":"1","key":"869_CR48","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s40249-018-0506-4","volume":"7","author":"S Liang","year":"2018","unstructured":"Liang S, Abe EM, Zhou XN. Integrating ecological approaches to interrupt schistosomiasis transmission: opportunities and challenges. Infect Dis Poverty. 2018;7(1):124.","journal-title":"Infect Dis Poverty"},{"issue":"2","key":"869_CR49","first-page":"101","volume":"20","author":"JR Dai","year":"2002","unstructured":"Dai JR, Zhou XN, Liang YS, Zhang YP, Jiang YJ, Xi WP, et al. Sensitivity of Oncomelania snail to niclosamide in China. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2002;20(2):101\u20135 (in Chinese).","journal-title":"Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi"},{"issue":"1","key":"869_CR50","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/s12929-020-0621-y","volume":"27","author":"AJ Molehin","year":"2020","unstructured":"Molehin AJ. Schistosomiasis vaccine development: update on human clinical trials. J Biomed Sci. 2020;27(1):28.","journal-title":"J Biomed Sci"},{"issue":"5","key":"869_CR51","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1586\/14760584.2016.1131127","volume":"15","author":"AJ Molehin","year":"2016","unstructured":"Molehin AJ, Rojo JU, Siddiqui SZ, Gray SA, Carter D, Siddiqui AA. Development of a schistosomiasis vaccine. Expert Rev Vaccines. 2016;15(5):619\u201327.","journal-title":"Expert Rev Vaccines"}],"container-title":["Infectious Diseases of Poverty"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40249-021-00869-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40249-021-00869-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40249-021-00869-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,12]],"date-time":"2021-06-12T12:05:08Z","timestamp":1623499508000},"score":1,"resource":{"primary":{"URL":"https:\/\/idpjournal.biomedcentral.com\/articles\/10.1186\/s40249-021-00869-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,12]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["869"],"URL":"https:\/\/doi.org\/10.1186\/s40249-021-00869-6","relation":{},"ISSN":["2049-9957"],"issn-type":[{"value":"2049-9957","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,12]]},"assertion":[{"value":"22 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 May 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All authors have provided consent for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"84"}}