{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T21:48:19Z","timestamp":1788558499301,"version":"build-2803163510"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T00:00:00Z","timestamp":1641427200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Eat Disord"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>For anorexia nervosa, firm evidence of the superiority of specialized psychological treatments is limited and economic evaluations of such treatments in real world settings are scarce. This consecutive cohort study examined differential (cost-)effectiveness for adult inpatients and outpatients with anorexia nervosa, after implementing cognitive behavioral therapy-enhanced (CBT-E) throughout a routine setting.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Differences in remission, weight regain and direct eating disorder treatment costs were examined between one cohort (<jats:italic>N<\/jats:italic>\u2009=\u200975) receiving treatment-as-usual (TAU) between 2012\u20132014, and the other (<jats:italic>N<\/jats:italic>\u2009=\u200988) CBT-E between 2015\u20132017. The economic evaluation was performed from a health care perspective with a one-year time horizon,\n using EDE global score\u2009&lt;\u20092.77, the absence of eating disorder behaviors combined with a BMI\u2009\u2265\u200918.5, as effect measure. Incremental cost-effectiveness ratios were calculated and cost-effectiveness planes and cost-effectiveness acceptability curves were displayed to assess the probability that CBT-E is cost effective compared to TAU.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Using direct eating disorder treatment costs in the cost-effectiveness analysis, the cost-effectiveness plane of the base case scenario for all patients indicated a 84% likelihood of CBT-E generating better health gain at additional costs. The median ICER is \u20ac51,081, indicating a probable preference for CBT-E (&gt;\u200950% probability of cost-effectiveness) assuming a WTP of \u20ac51,081 or more for each additional remission, On remission, no difference was found with 9.3% remission during TAU and 14.6% during CBT-E (<jats:italic>p<\/jats:italic>\u2009=\u2009.304). Weight regain was higher during CBT-E (<jats:italic>EMD<\/jats:italic>\u2009=\u20091.33\u00a0kg\/m<jats:sup>2<\/jats:sup>, <jats:italic>SE<\/jats:italic>\u2009=\u2009.29, 95% CI [0.76\u20131.9], <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>In this mixed inpatient and outpatient cohort study, findings indicate a probability of CBT-Ebeing more effective at higher costs. These findings may contribute to the knowledge of effectiveness and cost-effectiveness of specialized psychological treatments.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Plain English Summary<\/jats:title>\n                <jats:p>In this study, the effectiveness and treatment costs of a specialized psychological treatment for adult clients with anorexia nervosa were compared with a regular, non-specialist treatment. One group of inpatients and outpatients did receive non-specialist treatment, the next group of inpatients and outpatients received CBT-E, a specialized treatment, later on. CBT-E is recommended for clients with bulimia and with binge eating disorder, for clients with anorexia nervosa it is less clear which specialized psychological treatment should be recommended. Results indicate that at end-of-treatment, CBT-E was not superior on remission. When looking at weight regain, CBT-E seemed superior than the treatment offered earlier. Economic evaluation suggests that CBT-E generates better health gain, but at additional costs. This study contributes to the knowledge on the effectiveness and treatment costs of psychological treatments, as they are offered in routine practice, to adults with anorexia nervosa.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40337-021-00526-1","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T12:05:14Z","timestamp":1641470714000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Effectiveness and cost-effectiveness of cognitive behavior therapy-enhanced compared with treatment-as-usual for anorexia nervosa in an inpatient and outpatient routine setting: a consecutive cohort study"],"prefix":"10.1186","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3889-9897","authenticated-orcid":false,"given":"Elske","family":"van den Berg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3618-4465","authenticated-orcid":false,"given":"Daniela","family":"Schlochtermeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9309-8833","authenticated-orcid":false,"given":"Jitske","family":"Koenders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5449-171X","authenticated-orcid":false,"given":"Liselotte","family":"de Mooij","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5144-1119","authenticated-orcid":false,"given":"Margo","family":"de Jonge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8670-9384","authenticated-orcid":false,"given":"Anna E.","family":"Goudriaan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8821-3312","authenticated-orcid":false,"given":"Matthijs","family":"Blankers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4421-8744","authenticated-orcid":false,"given":"Jaap","family":"Peen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3782-6431","authenticated-orcid":false,"given":"Jack","family":"Dekker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"526_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fpsyt.2018.00158","volume":"9","author":"A Zeeck","year":"2018","unstructured":"Zeeck A, Herpertz-Dahlmann B, Friederich HC, Brockmeyer T, Resmark G, Hagenah U, et al. Psychotherapeutic treatment for anorexia nervosa: a systematic review and network meta-analysis. Front Psychiatry. 2018;9:1\u201314. https:\/\/doi.org\/10.3389\/fpsyt.2018.00158.","journal-title":"Front Psychiatry"},{"key":"526_CR2","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1002\/erv.2683","volume":"27","author":"E Van den Berg","year":"2019","unstructured":"Van den Berg E, Houtzager L, De Vos J, Daemen I, Katsaragaki G, Karyotaki E, et al. Meta-analysis on the efficacy of psychological treatments for anorexia nervosa. Eur Eat Disord Rev Rev. 2019;27:331\u201351. https:\/\/doi.org\/10.1002\/erv.2683.","journal-title":"Eur Eat Disord Rev Rev"},{"key":"526_CR3","doi-asserted-by":"publisher","first-page":"147","DOI":"10.5498\/wjp.v5.i1.147","volume":"5","author":"S Madden","year":"2015","unstructured":"Madden S, Hay P, Touyz S. Systematic review of evidence for different treatment settings in anorexia nervosa. World J Psychiatry. 2015;5:147\u201353. https:\/\/doi.org\/10.5498\/wjp.v5.i1.147.","journal-title":"World J Psychiatry"},{"key":"526_CR4","doi-asserted-by":"publisher","first-page":"CD010827","DOI":"10.1002\/14651858.CD010827.pub2","volume":"1","author":"P Hay","year":"2019","unstructured":"Hay P, Touyz S, Claudino A, Lujic S, Smith C, Madden S. Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders. Cochrane Database Syst Rev. 2019;1:CD010827. https:\/\/doi.org\/10.1002\/14651858.CD010827.pub2.","journal-title":"Cochrane Database Syst Rev"},{"key":"526_CR5","unstructured":"NICE National Institute for Health and Care Excellence. Eating disorders: recognition and treatment. Version 2.0. https:\/\/www.nice.org.uk\/guidance\/ng69."},{"key":"526_CR6","volume-title":"Cognitive behavior therapy and eating disorders","author":"CG Fairburn","year":"2008","unstructured":"Fairburn CG. Cognitive behavior therapy and eating disorders. Guilford Press; 2008."},{"key":"526_CR7","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.brat.2011.01.006","volume":"49","author":"S Byrne","year":"2011","unstructured":"Byrne S, Fursland A, Allen K, Watson H. The effectiveness of enhanced cognitive behavioural therapy for eating disorders: an open trial. Behav Res Ther. 2011;49:219\u201326. https:\/\/doi.org\/10.1016\/j.brat.2011.01.006.","journal-title":"Behav Res Ther"},{"key":"526_CR8","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.brat.2012.09.010","volume":"51","author":"C Fairburn","year":"2013","unstructured":"Fairburn C, Cooper Z, Doll H, O\u2019Connor M, Palmer R, Dalle GR. Enhanced cognitive behaviour therapy for adults with anorexia nervosa: a UK\u2013Italy study. Behav Res Ther. 2013;51:2\u20138. https:\/\/doi.org\/10.1016\/j.brat.2012.09.010.","journal-title":"Behav Res Ther"},{"key":"526_CR9","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.brat.2015.03.001","volume":"68","author":"H Turner","year":"2015","unstructured":"Turner H, Marshall E, Stopa L, Waller G. Cognitive behavioural therapy for outpatients with eating disorders: effectiveness for a transdiagnostic group in a routine clinical setting. Behav Res Ther. 2015;68:70\u20135. https:\/\/doi.org\/10.1016\/j.brat.2015.03.001.","journal-title":"Behav Res Ther"},{"key":"526_CR10","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1017\/S1352465817000352","volume":"4","author":"R Signorini","year":"2017","unstructured":"Signorini R, Sheffield J, Rhodes N, Fleming C, Ward W. The effectiveness of enhanced cognitive behavioural therapy (CBT-E): a naturalistic study within an outpatient eating disorder service. Behav Cogn Psychother. 2017;4:21\u201334. https:\/\/doi.org\/10.1017\/S1352465817000352.","journal-title":"Behav Cogn Psychother"},{"key":"526_CR11","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1186\/s40337-018-0198-y","volume":"6","author":"S Frostad","year":"2018","unstructured":"Frostad S, Danielsen Y, Rekkedal G, Jevne C, Dalle Grave R, \u00d8yvind R, et al. Implementation of enhanced cognitive behaviour therapy (CBT-E) for adults with anorexia nervosa in an outpatient eating-disorder unit at a public hospital. J Eat Disord. 2018;6:436\u201340. https:\/\/doi.org\/10.1186\/s40337-018-0198-y.","journal-title":"J Eat Disord"},{"key":"526_CR12","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1002\/eat.23428","volume":"54","author":"S Calugi","year":"2021","unstructured":"Calugi S, Sartirana M, Frostad S, Dalle GR. Enhanced cognitive behavior therapy for severe and extreme anorexia nervosa: an outpatient case series. Int J Eat Disord. 2021;54:305\u201312. https:\/\/doi.org\/10.1002\/eat.23428.","journal-title":"Int J Eat Disord"},{"key":"526_CR13","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1159\/000350058","volume":"82","author":"R Dalle Grave","year":"2013","unstructured":"Dalle Grave R, Calugi S, Conti M, Doll H, Fairburn CG. Inpatient cognitive behaviour therapy for anorexia nervosa: a randomized controlled trial. Psychother Psychosom. 2013;82:390\u20138. https:\/\/doi.org\/10.1159\/000350058.","journal-title":"Psychother Psychosom"},{"key":"526_CR14","doi-asserted-by":"publisher","DOI":"10.1111\/cpsp.12221","volume":"25","author":"H Thompson-Brenner","year":"2018","unstructured":"Thompson-Brenner H, Brooks GE, Boswell JF, Espel-Huynh H, Dore R, Franklin D, et al. Evidence-based implementation practices applied to the intensive treatment of eating disorders: summary of research and illustration of principles using a case example. Clin Psychol. 2018;25: e12221. https:\/\/doi.org\/10.1111\/cpsp.12221.","journal-title":"Clin Psychol"},{"key":"526_CR15","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1002\/eat.22087","volume":"46","author":"S Crow","year":"2013","unstructured":"Crow S, Agras W, Halmi K, Fairburn C, Mitchell J, Nyman J. A cost effectiveness analysis of stepped care treatment for bulimia nervosa. Int J Eat Disord. 2013;46:302\u20137. https:\/\/doi.org\/10.1002\/eat.22087.","journal-title":"Int J Eat Disord"},{"issue":"4","key":"526_CR16","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1177\/0004867417739690","volume":"52","author":"LK-D Le","year":"2018","unstructured":"Le LK-D, Hay P, Mihalopoulos C. A systematic review of cost-effectiveness studies of prevention and treatment for eating disorders. Aust N Z J Psychiatry. 2018;52(4):328\u201338. https:\/\/doi.org\/10.1177\/0004867417739690.","journal-title":"Aust N Z J Psychiatry"},{"key":"526_CR17","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1192\/bjp.bp.107.036806","volume":"191","author":"S Byford","year":"2007","unstructured":"Byford S, Barrett B, Roberts C, Clark A, Edwards V, Smethurst N, et al. Economic evaluation of a randomized controlled trial for anorexia nervosa in adolescents. Br J Psychiat. 2007;191:436\u201340. https:\/\/doi.org\/10.1192\/bjp.bp.107.036806.","journal-title":"Br J Psychiat"},{"key":"526_CR18","doi-asserted-by":"publisher","first-page":"3291","DOI":"10.1017\/S0033291716002002","volume":"46","author":"N Egger","year":"2016","unstructured":"Egger N, Wild B, Zipfel S, Junne F, Konnopka A, Schmidt U, et al. Cost-effectiveness of focal psychodynamic therapy and enhanced cognitive-behavioural therapy in out-patients with anorexia. Psychol Med. 2016;46:3291\u2013301. https:\/\/doi.org\/10.1017\/S0033291716002002.","journal-title":"Psychol Med"},{"key":"526_CR19","volume-title":"Diagnostic and statistical manual of mental disorders: DSM-IV","author":"American Psychiatric Association","year":"1994","unstructured":"American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-IV. American Psychiatric Association Publishing; 1994."},{"key":"526_CR20","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"2013","unstructured":"American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. American Psychiatric Association Publishing; 2013.","edition":"5"},{"key":"526_CR21","volume-title":"Cognitive behavior therapy and eating disorders","author":"CG Fairburn","year":"2008","unstructured":"Fairburn CG, Beglin SJ. Eating disorder examination questionnaire (6.0). In: Fairburn CG, editor. Cognitive behavior therapy and eating disorders. Guilford Press; 2008."},{"key":"526_CR22","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.eatbeh.2012.09.002","volume":"13","author":"JJ Aardoom","year":"2012","unstructured":"Aardoom JJ, Dingemans AE, Slof Op \u2019t Landt MCT, Van Furth EF. Norms and discriminative validity of the Eating Disorders Examination Questionnaire (EDE-Q). Eat Behav. 2012;13:305\u20139. https:\/\/doi.org\/10.1016\/j.eatbeh.2012.09.002.","journal-title":"Eat Behav"},{"key":"526_CR23","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/0005-7967(94)00075-U","volume":"33","author":"PF Lovibond","year":"1995","unstructured":"Lovibond PF, Lovibond SH. The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety inventories. Behav Res Ther. 1995;33:335\u201343. https:\/\/doi.org\/10.1016\/0005-7967(94)00075-U.","journal-title":"Behav Res Ther"},{"key":"526_CR24","first-page":"35","volume":"34","author":"E De Beurs","year":"2001","unstructured":"De Beurs E, Van Dyck R, Marquenie LA, Lange A, Blonk RWB. De DASS: een vragenlijst voor het meten van depressie, angst en stress. Gedragstherapie. 2001;34:35\u201353.","journal-title":"Gedragstherapie"},{"key":"526_CR25","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.brat.2004.12.003","volume":"44","author":"J Mond","year":"2006","unstructured":"Mond J, Hay P, Rodgers B, Owen C. Eating Disorder Examination Questionnaire (EDE-Q): norms for young adult women. Behav Res Ther. 2006;44:53\u201362. https:\/\/doi.org\/10.1016\/j.brat.2004.12.003.","journal-title":"Behav Res Ther"},{"key":"526_CR26","doi-asserted-by":"publisher","first-page":"702","DOI":"10.12688\/f1000research.7618.1","volume":"5","author":"G Waller","year":"2016","unstructured":"Waller G. Recent advances in psychological therapies for eating disorders. F1000Res. 2016;5:702. https:\/\/doi.org\/10.12688\/f1000research.7618.1.","journal-title":"F1000Res"},{"key":"526_CR27","first-page":"231","volume-title":"Cognitive behavior therapy and eating disorders","author":"R Dalle Grave","year":"2008","unstructured":"Dalle Grave R, Bohn K, Hawker D, Fairburn CG. Inpatient, day patient and two forms of outpatient CBT-E. In: Fairburn CG, editor. Cognitive behavior therapy and eating disorders. Guilford Press; 2008. p. 231\u201344."},{"key":"526_CR28","first-page":"86","volume":"50","author":"E Van den Berg","year":"2017","unstructured":"Van den Berg E, Schlochtermeier D, Goudriaan A, Dekker J. Implementatie van cognitive behavioral therapy-enhanced in een regulier behandelcentrum voor eetstoornissen. Tijdschrift voor Gedragstherapie. 2017;50:86\u2013101.","journal-title":"Tijdschrift voor Gedragstherapie"},{"key":"526_CR29","unstructured":"Zorginstituut Nederland. Richtlijn voor het uitvoeren van economische evaluaties in de gezondheidszorg [Guideline for economic evaluations in health care]. https:\/\/www.zorginstituutnederland.nl\/publicaties\/publicatie\/2016\/02\/29\/richtlijn-voorhet-uitvoeren-van-economische-evaluaties-in-de-gezondheidszorg."},{"key":"526_CR30","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1002\/hec.4730030505","volume":"3","author":"BA Van Hout","year":"1994","unstructured":"Van Hout BA, Al MJ, Gordon GS, Rutten FF. Costs, effects and C\/E-ratios alongside a clinical trial. Health Econ. 1994;3:309\u201319. https:\/\/doi.org\/10.1002\/hec.4730030505.","journal-title":"Health Econ"},{"key":"526_CR31","doi-asserted-by":"publisher","DOI":"10.1002\/9780470316696","volume-title":"Multiple imputation for nonresponse in surveys","author":"BD Rubin","year":"1987","unstructured":"Rubin BD. Multiple imputation for nonresponse in surveys. Wiley; 1987."},{"issue":"1","key":"526_CR32","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1037\/amp0000191","volume":"73","author":"M Applebaum","year":"2018","unstructured":"Applebaum M, Cooper H, Kline R, Mayo-Wilson E, Nezu A, Rao S. Journal article reporting standards for quantitative research in psychology: the APA publications and communications board task force report. Am Psychol. 2018;73(1):3\u201325. https:\/\/doi.org\/10.1037\/amp0000191.","journal-title":"Am Psychol"},{"key":"526_CR33","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1097\/EDE.0b013e3181577511","volume":"18","author":"JP Vandenbroucke","year":"2007","unstructured":"Vandenbroucke JP, Von Elm E, Altman DG, G\u00f8tzsche PC, Mulrow CD, Pocock SJ, et al. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Epidemiology. 2007;18:805\u201335. https:\/\/doi.org\/10.1097\/EDE.0b013e3181577511.","journal-title":"Epidemiology"},{"key":"526_CR34","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.jval.2013.02.002","volume":"16","author":"D Husereau","year":"2013","unstructured":"Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, et al. Consolidated health economic evaluation reporting standards (CHEERS)\u2014explanation and elaboration: a report of the ISPOR health economic evaluations publication guidelines task force. Value Health. 2013;16:231\u201350. https:\/\/doi.org\/10.1016\/j.jval.2013.02.002.","journal-title":"Value Health"},{"key":"526_CR35","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1002\/1098-108X(199412)16:4<363::AID-EAT2260160405>3.0.CO;2-#","volume":"16","author":"CG Fairburn","year":"1994","unstructured":"Fairburn CG, Beglin SJ. Assessment of eating disorders: interview or self-report questionnaire? Int J Eat Disord. 1994;16:363\u201370.","journal-title":"Int J Eat Disord"},{"key":"526_CR36","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1002\/eat.23229","volume":"53","author":"E van den Berg","year":"2020","unstructured":"van den Berg E, Schlochtermeier D, Koenders J, et al. Implementing cognitive behavioral therapy-enhanced in a routine inpatient and outpatient setting: comparing effectiveness and treatment costs in two consecutive cohorts. Int J Eat Disord. 2020;53:461\u201371. https:\/\/doi.org\/10.1002\/eat.23229.","journal-title":"Int J Eat Disord"},{"key":"526_CR37","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1002\/eat.22274","volume":"48","author":"N Stuhldreher","year":"2012","unstructured":"Stuhldreher N, Wild B, K\u00f6nig H-H, Konnopka A, Zipfel S, Herzog W. Determinants of direct and indirect costst in anorexia nervosa. Int J Eat Disord. 2012;48:139\u201346. https:\/\/doi.org\/10.1002\/eat.22274.","journal-title":"Int J Eat Disord"},{"key":"526_CR38","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.1002\/eat.23337","volume":"53","author":"R Dalle Grave","year":"2020","unstructured":"Dalle Grave R, Conti M, Calugi S. Effectiveness of intensive cognitive behavioral therapy in adolescents and adults with anorexia nervosa. Int J Eat Disord. 2020;53:1428\u201338. https:\/\/doi.org\/10.1002\/eat.23337.","journal-title":"Int J Eat Disord"},{"key":"526_CR39","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/S0140-6736(17)32133-5","volume":"391","author":"D Clark","year":"2018","unstructured":"Clark D, Canvin L, Green J, Layard R, Pilling S, Janecka M. Transparency about the outcomes of mental health services (IAPT approach): an analysis of public data. Lancet. 2018;391:676\u201386. https:\/\/doi.org\/10.1016\/S0140-6736(17)32133-5.","journal-title":"Lancet"},{"issue":"8","key":"526_CR40","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1002\/eat.23283","volume":"53","author":"SA Wonderlich","year":"2020","unstructured":"Wonderlich SA, Bulik CM, Schmidt U, Steiger H, Hoek HW. Severe and enduring anorexia nervosa: update and observations about the current clinical reality. Int J Eat Disord. 2020;53(8):1303\u201312. https:\/\/doi.org\/10.1002\/eat.23283.","journal-title":"Int J Eat Disord"}],"container-title":["Journal of Eating Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40337-021-00526-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40337-021-00526-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40337-021-00526-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T12:09:59Z","timestamp":1641470999000},"score":1,"resource":{"primary":{"URL":"https:\/\/jeatdisord.biomedcentral.com\/articles\/10.1186\/s40337-021-00526-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,6]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["526"],"URL":"https:\/\/doi.org\/10.1186\/s40337-021-00526-1","relation":{},"ISSN":["2050-2974"],"issn-type":[{"value":"2050-2974","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,6]]},"assertion":[{"value":"3 September 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors assert that all procedures contributing to this work comply with the ethical standards of relevant national and institutional committees on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008. All procedures involving patients were approved by The Dutch Central Committee on Human Research; informed consent, as part of routine service evaluation, was obtained from all patients.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"2"}}