{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T04:11:21Z","timestamp":1748319081729,"version":"3.41.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"NTNU Norwegian University of Science and Technology"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Eat Disord"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>The incidence of anorexia nervosa (AN) has increased over the past decade, particularly among school-aged children. Family-based therapy (FBT), which focuses on parental management and control, is the recommended and standard treatment for adolescents with AN. While FBT promotes weight gain and improved parent\u2012child interactions, it does not directly address the adolescents\u2019 cognitive change, which could make them vulnerable to relapse. Metacognitive therapy is scarcely studied in AN, and this trial tested its feasibility and long-term effects for adolescents with AN.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This phase II trial included 14 adolescents with AN in an A\u2012B design. Medical tests and diagnostic assessments were conducted before and after treatment. Assessments were conducted before treatment, by end of treatment and at 12\u00a0months after end of treatment. We integrated family-based treatment and metacognitive therapy for patient intervention and parental guidance.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>At posttreatment, 13 of the 14 patients no longer met the diagnostic criteria for AN. There were significant increases in percentage expected body weight and reductions in emotional and cognitive symptoms. One patient continued to have eating disorder symptoms at posttreatment and withdrew before follow-up. No significant changes were observed in areas of family conflict or parent\u2012child communication. The treatment was well tolerated and deemed meaningful by both parents and patients. No adverse events or rehospitalization occurred during the 12\u00a0month follow-up period. Data collection was challenging, especially with respect to patients\u2019 disclosure of family interactions and symptoms.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>The trial revealed positive effects posttreatment at the 12\u00a0month follow-up for 13 of 14 participants with AN. The treatment was well tolerated with no adverse effects. Despite the small sample size and lack of control, the results suggest that larger-scale trials of this intervention are warranted.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Trial registration<\/jats:title>\n            <jats:p>The study has been approved as a clinical and quality audit of the delivered clinical service registered by the institutional research board at Levanger Hospital HF (IRB-13672).<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s40337-025-01272-4","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T11:16:21Z","timestamp":1748258181000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Family-based treatment with metacognitive therapy for adolescents with anorexia nervosa: findings from a phase II trial"],"prefix":"10.1186","volume":"13","author":[{"given":"Beate","family":"\u00d8stg\u00e5rd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunn Julie D.","family":"Nordahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arve","family":"Strandheim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans M.","family":"Nordahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"key":"1272_CR1","doi-asserted-by":"publisher","first-page":"e2222079","DOI":"10.1001\/jamanetworkopen.2022.22079","volume":"5","author":"P Sur\u00e9n","year":"2022","unstructured":"Sur\u00e9n P, Skirbekk AB, Torgersen L, Bang L, God\u00f8y A, Hart RK. 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Given this context, review and approval by a research ethics committee were attained, but we followed the institutional (BUP, Levanger) and Norwegian health ethics (REK) guidelines. Human ethics and consent to participate declarations: Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human ethics and consent to participate"}},{"value":"The consent form allowed patients to decide whether to grant hospital permission to use their clinical data anonymously for clinical and quality audit purposes. Written informed consent was obtained from both parents and children aged 16\u00a0years and above.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"HMN is engaged in the training and education of therapists in MCT and has received a salary for providing training and workshops. B\u00d8, AS, and GJN have reported no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"91"}}