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Most ED screening instruments have been validated in predominately cisgender, heterosexual female samples limiting their generalizability to populations with different symptom patterns. Validation studies in cisgender sexual minority (SM) adults are critical to improving detection and addressing disparities in ED identification. The present study evaluated the psychometric performance of the Brief Assessment of Stress and Eating (BASE), a validated 10-item screening tool that assesses DSM-5-aligned eating disorder symptoms and subclinical dysregulated eating behaviors, in a national sample of cisgender gay men and lesbian women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were 1,499 cisgender SM adults (61.7% gay men, 38.3% lesbian women) recruited from The PRIDE Study, a U.S.-based longitudinal cohort of sexual and gender minority adults. Respondents completed the BASE, SCOFF questionnaire, and the Eating Disorder Diagnostic Scale-5 (EDDS-5) which we used to derive probable DSM-5 eating disorder (probable ED) status. Receiver operating characteristic (ROC) and precision\u2013recall (PR) curve analyses were conducted to evaluate classification accuracy and identify optimal thresholds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both the BASE and SCOFF performed significantly above chance in detecting EDDS-5-derived probable EDs. Among gay men, the BASE (AUC: ROC\u2009=\u20090.785, PRC\u2009=\u20090.702) outperformed the SCOFF (ROC\u2009=\u20090.744, PRC\u2009=\u20090.630). In lesbian women, the two screeners performed similarly (BASE AUC\u2009=\u20090.807; SCOFF AUC\u2009=\u20090.806). Optimal BASE thresholds varied by group with higher sensitivity at lower cutoffs (e.g., \u2265 7).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The BASE provides a reliable, efficient alternative to traditional instruments for screening eating disorders in sexual minority adults, with good performance for identifying EDDS-5\u2013derived probable EDs. Findings support the BASE as a reliable and valid screening tool for use with cisgender SM adults in community, healthcare, and research contexts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s40337-025-01482-w","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T03:55:22Z","timestamp":1764906922000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Validation of the Brief Assessment of Stress and Eating (BASE) in cisgender gay men and lesbian women"],"prefix":"10.1186","volume":"14","author":[{"given":"Jason M.","family":"Nagata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher D.","family":"Otmar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Char","family":"Potes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason M.","family":"Lavender","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio J.","family":"Compte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffany A.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelsie T.","family":"Forbush","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annesa","family":"Flentje","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juno","family":"Obedin-Maliver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell R.","family":"Lunn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"key":"1482_CR1","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1080\/10640266.2024.2328460","volume":"32","author":"T Alexander","year":"2024","unstructured":"Alexander T, Burnette CB, Cory H, McHale S, Simone M. 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All procedures performed in this study were in accordance with the ethical standards of the university\u2019s Institutional Review Board and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from all participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Dr. Obedin-Maliver has received consulting fees from Sage Therapeutics, Ibis Reproductive Health, Folx Health, Inc., Hims and Hers Health, Inc., and Upstream, Inc. Dr. Lunn received consultation fees from Hims and Hers Health, Inc., Folx Health Inc., Otsuka Pharmaceutical Development and Commercialization, Inc., and the American Dental Association on topics unrelated to this work. None of these roles present a conflict of interest with this work as described here. The other authors have no conflicts of interest to report.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"28"}}