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Yet studies of resilience suggest most individuals will successfully negotiate this challenge and some may even experience growth and positive change. Some evidence suggests that the capacity to enact positive change in the face of adversity may be shaped by early life experiences.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In a subset of 374 participants (57% female, mean age\u2009=\u200929\u00a0years) in the Study of Early Child Care and Youth Development (SECCYD), a longitudinal, birth cohort, prospective models were tested to determine whether early life adversities in family and neighborhood contexts predict positive change events in response to the COVID-19 pandemic. Childhood family and neighborhood contexts were assessed using a combination of self-report questionnaires and US Census data. Adulthood positive change events (e.g., becoming more appreciative of things usually taken for granted) were assessed using the Epidemic-Pandemic Impacts Inventory (EPII).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In regression analyses, neighborhood disadvantage in childhood, measured both by objective and subjective assessments, predicted a higher number of positive change events in response to the COVID-19 pandemic (<jats:italic>\u03b2<\/jats:italic>\u2009=\u2009.18, <jats:italic>p<\/jats:italic>\u2009=\u2009.004 and <jats:italic>\u03b2<\/jats:italic>\u2009=\u2009.15, <jats:italic>p<\/jats:italic>\u2009=\u2009.006, respectively). Examination of the positive change event subscales showed neighborhood disadvantage in childhood predicted increases in events related to \u2018perspective taking and charitable giving\u2019 (<jats:italic>\u03b2<\/jats:italic>\u2009=\u2009.20, <jats:italic>p<\/jats:italic>\u2009=\u2009.022 and <jats:italic>\u03b2<\/jats:italic>\u2009=\u2009.17, <jats:italic>p<\/jats:italic>\u2009=\u2009.002, respectively) and improved \u2018social relationships\u2019 (<jats:italic>\u03b2<\/jats:italic>\u2009=\u2009.18, <jats:italic>p<\/jats:italic>\u2009=\u2009.004 and <jats:italic>\u03b2<\/jats:italic>\u2009=\u2009.13, <jats:italic>p<\/jats:italic>\u2009=\u2009.020, respectively), but not to positive \u2018health behaviors\u2019 (<jats:italic>ps<\/jats:italic>\u2009&gt;\u2009.05). All associations were independent of sociodemographic factors and childhood family dysfunction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Findings suggest that neighborhood disadvantage in childhood may shape prosocial responses to stress in adulthood, potentially through early life adaptions to stress that are protective when facing adversity. There are several notable implications of the study findings. Although adversity in early life has clear negative impacts, it is possible that adversity experiences may also provide opportunities to develop adaptive strategies that foster resilience and growth when facing stress. Intervention efforts should consider leveraging such stress-adapted strengths to reduce the many negative impacts of early life adversity.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40359-021-00586-7","type":"journal-article","created":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T12:03:48Z","timestamp":1621339428000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Early life predictors of positive change during the coronavirus disease pandemic"],"prefix":"10.1186","volume":"9","author":[{"given":"Maria E.","family":"Bleil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley M.","family":"Appelhans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexis S.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven E.","family":"Gregorich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neal","family":"Marquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn I.","family":"Roisman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathryn","family":"Booth-LaForce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyle","family":"Crowder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,18]]},"reference":[{"key":"586_CR1","doi-asserted-by":"crossref","unstructured":"Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, et al. 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Informed consent for the SECCYD follow-up study, SHINE, was obtained from the now adult children. For the SECCYD, the research was approved by the Institutional Review Boards (IRB) of each university-based study site (e.g., University of California, Irvine IRB; University of Virginia IRB Social and Behavioral Science; Temple University Human Research Protection Program). For SHINE, the research was approved by the Human Subjects Division of the University of Washington.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"83"}}