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This descriptive study examined the demographic, clinical, and laboratory findings of patients with fungal poisoning, a type of fungus causing the poisoning, and the incidence and mortality rates of fungal poisoning in Kermanshah province, western Iran, from 2014 to 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of 193 patients with mushroom poisoning from 2014 to 2018 were evaluated. The liver and kidney function tests, electrolytes, abdominal and pelvic ultrasound, chest x-ray, coagulation tests, and coagulation factors (fibrinogen, prothrombin) were assessed. Data were collected from the medical records of patients admitted to the Poisoning Center of Imam Khomeini Hospital in Kermanshah, Iran using a researcher-made checklist. Data were analyzed by SPSS (version 16) using descriptive statistics, including mean, standard deviation, and frequency distribution tables. Trend analysis for proportion was done by chi-square statistics in STATA-14 software (ptrend command).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of cases, \u200c51.3% were male, 92.6% were city dwellers, 38.3% were aged 21\u201340 years, and 92.5% were poisoned during the spring. The fungus that caused poisoning was<jats:italic>Amanita virosa.<\/jats:italic>The gastrointestinal, nervous, and visual systems were the most common systems involved. The most common gastrointestinal symptoms included nausea and vomiting (72.0%) and abdominal pain (71.0%). Vertigo (11.9%) and headache (9.3%) were the most common neurological symptoms. The most common visual manifestation was blurred vision (7.8%). Of cases, 23.7% had metabolic acidosis. The increased alkaline phosphatase level was the most common liver disorder in 98.7% of the cases. Increased blood urea nitrogen and creatinine levels were also reported in 21.0% and 17.7% of the cases, respectively. The serum lactic dehydrogenase and creatine phosphokinase levels also increased in 99.3% and 30.2% of the patients, respectively. The mortality rate was 1.6% (n\u2009=\u20093).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The fungal poisoning diagnosis should always be considered in young patients referred to the emergency department with gastrointestinal complaints, a history of consuming wild self-picked mushrooms, and high liver and kidney test values. Since most fungal poisonings occur in the spring, it is necessary to inform the community of the dangers of consuming self-picked wild mushrooms, especially in this season.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s40360-022-00614-1","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T14:03:31Z","timestamp":1664201011000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Demographic, clinical, and laboratory findings of mushroom-poisoned patients in Kermanshah province, west of Iran"],"prefix":"10.1186","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1450-1554","authenticated-orcid":false,"given":"Maryam","family":"Janatolmakan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Rouhi","family":"Ganji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8956-9655","authenticated-orcid":false,"given":"Touraj","family":"Ahmadi-Jouybari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5094-5315","authenticated-orcid":false,"given":"Shahab","family":"Rezaeian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2243-696X","authenticated-orcid":false,"given":"Mahnaz","family":"Ghowsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3552-5539","authenticated-orcid":false,"given":"Alireza","family":"Khatony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,26]]},"reference":[{"issue":"2","key":"614_CR1","doi-asserted-by":"publisher","first-page":"94","DOI":"10.4166\/kjg.2018.71.2.94","volume":"71","author":"SY Kim","year":"2018","unstructured":"Kim SY, Baek Y-H, Han SY, Lee SW, Roh YH, Kim KW, et al. 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In the current study, information was obtained from the patients\u2019 records, and their data were kept confidential. Therefore, according to the regulations of the Ethics Committee of Kermanshah University of Medical Sciences, there was no need to obtain a consent from these patients. All methods were carried out in accordance with relevant guidelines and regulations. Further, all experimental protocols were approved by the ethics committee of Kermanshah University of Medical Sciences.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare that they have no conflicts of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"72"}}