{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:58:20Z","timestamp":1793051900223,"version":"4.5.0"},"reference-count":9,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Otolaryngology - Head &amp; Neck Surgery"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> We report an unusual case of a 66-year-old female with a suspicious thoracic outlet mass presenting with severe biochemical hyperparathyroidism and classic hypercalcemic symptoms of renal and bone involvement. <\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p> There was clinical suspicion for parathyroid carcinoma, further supported by intra-operative findings. However, the final pathology described a primary hyperceullar parathyroid lesion with pathognomonic changes secondary to fine-needle aspiration (FNA) biopsy, along with a separate parathyroid lesion likely resulting from seeding along the needle tract. Upon further review, record of a remote FNA was discovered. This case highlights the complications associated with parathyroid FNA resulting in a diagnostic challenge and raising the possibility of malignancy. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> We therefore recommend to take caution when there is a prior parathyroid FNA, as it can present with the risks of a secondary lesion from seeding and increase resemblance of malignancy both clinically and through pathologic diagnosis. <\/jats:p><\/jats:sec>","DOI":"10.1186\/s40463-016-0178-7","type":"journal-article","created":{"date-parts":[[2017,1,7]],"date-time":"2017-01-07T00:52:56Z","timestamp":1483750376000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":61,"title":["The dangers of parathyroid biopsy"],"prefix":"10.1177","volume":"46","author":[{"given":"Joanne","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Otolaryngology (ENT), Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, M4N 3M5, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilad","family":"Horowitz","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology (ENT), Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, M4N 3M5, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology (ENT), Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, M4N 3M5, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Orsini","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology (ENT), Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, M4N 3M5, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia L.","family":"Asa","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Health Network (UHN), 200 Elizabeth Street, 11th Floor, M5G 2C4, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5760-1390","authenticated-orcid":false,"given":"Kevin","family":"Higgins","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology (ENT), Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, M4N 3M5, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,1,1]]},"reference":[{"key":"bibr1-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1002\/dc.21020"},{"key":"bibr2-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2007.0081"},{"key":"bibr3-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2005.029017"},{"key":"bibr4-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-006-0095-8"},{"key":"bibr5-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(90)90136-S"},{"key":"bibr6-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1007\/s12022-012-9222-y"},{"key":"bibr7-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000234"},{"key":"bibr8-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2010.01.011"},{"key":"bibr9-s40463-016-0178-7","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11819"}],"container-title":["Journal of Otolaryngology - Head &amp; Neck Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1186\/s40463-016-0178-7","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1186\/s40463-016-0178-7","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40463-016-0178-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1186\/s40463-016-0178-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T15:23:13Z","timestamp":1741620193000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1186\/s40463-016-0178-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1186\/s40463-016-0178-7"],"URL":"https:\/\/doi.org\/10.1186\/s40463-016-0178-7","relation":{},"ISSN":["1916-0216","1916-0216"],"issn-type":[{"value":"1916-0216","type":"print"},{"value":"1916-0216","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1]]},"article-number":"4"}}