{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T05:14:27Z","timestamp":1768454067184,"version":"3.49.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Otolaryngology - Head &amp; Neck Surgery"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> The objective of this study was to validate our approach of treating primary hyperparathyroidism using sestamibi scan directed parathyroidectomy, without routine use of intraoperative parathyroid hormone measurements (ioPTH). <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> We prospectively established a protocol limiting the use of ioPTH to patients with negative or equivocal sestamibi scans, and those who had risk factors for multi-gland disease. We then performed a retrospective review to determine our disease control rate. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> 128 patients underwent sestamibi-guided parathyroidectomy without (111\/128\u2009=\u200987%) or with (17\/128\u2009=\u200913%) ioPTH. The overall disease control (eucalcemia) rate was 95%. 3\/111 (3%) of patients who had surgery without ioPTH measurements required re-exploration. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> Selective use of ioPTH is an effective strategy. ioPTH is best reserved for patients who have non-localizing preoperative imaging, are at risk for multi-gland disease, or require revision surgery. <\/jats:p><\/jats:sec>","DOI":"10.1186\/s40463-017-0188-0","type":"journal-article","created":{"date-parts":[[2017,2,6]],"date-time":"2017-02-06T12:17:48Z","timestamp":1486383468000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Validation of selective use of intraoperative PTH monitoring in parathyroidectomy"],"prefix":"10.1177","volume":"46","author":[{"given":"Alexandra","family":"Thielmann","sequence":"first","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, University of Manitoba, Winnipeg, Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Kerr","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, University of Manitoba, Winnipeg, Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,1,1]]},"reference":[{"key":"bibr1-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7469-2"},{"key":"bibr2-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2015.0048"},{"key":"bibr3-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1186\/1916-0216-42-56"},{"key":"bibr4-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-002-6675-z"},{"key":"bibr5-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-013-1080-7"},{"key":"bibr6-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1460783"},{"key":"bibr7-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.5.559"},{"key":"bibr8-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-016-0666-7"},{"key":"bibr9-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60507-9"},{"key":"bibr10-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.5152\/UCD.2014.2572"},{"key":"bibr11-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.14366\/usg.14071"},{"key":"bibr12-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2007.02827.x"},{"key":"bibr13-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(97)90108-2"},{"key":"bibr14-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(96)00289-9"},{"issue":"3","key":"bibr15-s40463-017-0188-0","first-page":"313","volume":"33","author":"O'Doherty MJ","year":"1992","journal-title":"J Nucl Med"},{"issue":"2016","key":"bibr16-s40463-017-0188-0","first-page":"82","volume":"25","author":"Medas F","year":"2015","journal-title":"Int J Surg"},{"key":"bibr17-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2008.03.019"},{"key":"bibr18-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2004.04.013"},{"key":"bibr19-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-010-0724-0"},{"key":"bibr20-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-002-6695-8"},{"key":"bibr21-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1053\/ejso.2000.1004"},{"key":"bibr22-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1177\/000313480306900507"},{"key":"bibr23-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2015.89.3.111"},{"key":"bibr24-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2004.06.024"},{"key":"bibr25-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.4158\/EP10304.RA"},{"key":"bibr26-s40463-017-0188-0","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-008-0283-9"}],"container-title":["Journal of Otolaryngology - Head &amp; 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