{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T20:38:10Z","timestamp":1775767090874,"version":"3.50.1"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Otolaryngology - Head &amp; Neck Surgery"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> With an increase in the incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) and more favourable survival outcomes, there is now a population of head and neck cancer survivors that are different from preceding decades. In addition, their long-term survivorship issues have become increasing research interests. This study was undertaken to determine the changing epidemiological trends of head and neck cancer survivors in Alberta to better anticipate future demands on healthcare services. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> The Alberta Cancer Registry was queried for adult (aged &gt;\u200918\u2009years), head and neck cancer (HNC) patients who were at least 1-year post-treatment completion between 1997 to 2016. Cutaneous head and neck and thyroid cancer patients were excluded. Extracted data was then used to calculate the incidence and prevalence of early (&lt;\u20095\u2009years from treatment), intermediate (5 to &lt;\u200910\u2009years from treatment), and late (&gt;\u200910\u2009years from treatment) survivors of head and neck cancer. Point prevalence of HNC survivors in 2005, 2010, and 2015 were then further stratified by gender, sub-site and age. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Over this time period, head and neck cancer survivors tended to be younger (64.0 vs. 62.1, p\u2009=\u20090.046) and male (M:F 2.45:1 vs 2.54:1). In 1997, the predominant subsites were the oral cavity and larynx at 45.8% and 30.9%, respectively. In 2015 the predominant subsites were the oral cavity and oropharynx at 33.0% and 29.4%, respectively. Within the cohort, the prevalence of late HNC survivors increased to 13.3 per 100,000 people in 2015. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> There is a significant population of head and neck survivors who are younger, male, and more than 10\u00a0years post-treatment. While oral cavity cancers have shown stable disease prevalence in recent decades, the number of OPSCC survivors have increased. With an improved understanding of the distribution and characteristics of HNC survivors, a more guided healthcare support network can be fostered for these patients. <\/jats:p><\/jats:sec>","DOI":"10.1186\/s40463-020-00443-4","type":"journal-article","created":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T13:03:52Z","timestamp":1594040632000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Epidemiological trends of head and neck Cancer survivors in Alberta: Towards improved understanding of the burden of disease"],"prefix":"10.1177","volume":"49","author":[{"given":"Jin Soo","family":"Song","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada"},{"name":"Division of Otolaryngology \u2013 Head & Neck Surgery, Department of Surgery, University of Alberta, 1E4 Walter Mackenzie Centre, 8440-112 Street NW, T6G 2B7, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Vallance","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Biron","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada"},{"name":"Division of Otolaryngology \u2013 Head & Neck Surgery, Department of Surgery, University of Alberta, 1E4 Walter Mackenzie Centre, 8440-112 Street NW, T6G 2B7, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5536-4915","authenticated-orcid":false,"given":"Caroline C.","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada"},{"name":"Division of Otolaryngology \u2013 Head & Neck Surgery, Department of Surgery, University of Alberta, 1E4 Walter Mackenzie Centre, 8440-112 Street NW, T6G 2B7, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,1,1]]},"reference":[{"key":"bibr1-s40463-020-00443-4","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2013.09.011"},{"key":"bibr2-s40463-020-00443-4","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2018.06.001"},{"key":"bibr3-s40463-020-00443-4","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2016.5688"},{"key":"bibr4-s40463-020-00443-4","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2017.05.008"},{"key":"bibr5-s40463-020-00443-4","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812437332"},{"key":"bibr6-s40463-020-00443-4","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21565"},{"key":"bibr7-s40463-020-00443-4","author":"Canadian Cancer Society's Advisory Committee on Cancer Statistics","year":"2017","journal-title":"Canadian Cancer Statistics 2017"},{"key":"bibr8-s40463-020-00443-4","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2017.11.005"},{"key":"bibr9-s40463-020-00443-4","doi-asserted-by":"publisher","DOI":"10.1111\/1460-6984.12071"},{"issue":"1","key":"bibr10-s40463-020-00443-4","first-page":"S56","volume":"41","author":"Dziegielewski PT","year":"2012","journal-title":"J Otolaryngol Head Neck"},{"key":"bibr11-s40463-020-00443-4","unstructured":"https:\/\/open.alberta.ca\/publications\/4170782. 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