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Regarding sigmoid biopsies sampling, the study protocol was approved by the local Committee on Ethics and Human Research (\n            Comit\u00e9 de Protection des Personnes Ouest VI\n            ), and registered on ClinicalTrials.gov (EnteroLark and ColoBioParker, identifier NCT01618383 and NCT01353183, respectively). Written informed consent was obtained from each patient and from each normal volunteer.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Michael S. Perkinton is an employee of MedImmune.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"65"}}