{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T23:55:29Z","timestamp":1781654129245,"version":"3.54.5"},"reference-count":101,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T00:00:00Z","timestamp":1705536000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T00:00:00Z","timestamp":1705536000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004360","name":"Swedish University of Agricultural Sciences","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004360","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Canine Med Genet"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The English Cocker Spaniel (ECS) is one of the most popular dog breeds in the UK but information on disorder predisposition and protection is limited. Using anonymised veterinary clinical data from the VetCompass\u2122 Programme, this study aimed to compare disorder predisposition and protection between the ECS and the remaining dogs under primary veterinary care in the UK during 2016. Electronic patient records for random samples of ECS and non-ECS were reviewed. The most common disorders diagnosed during 2016 were extracted and compared using multivariable logistic regression, controlling for confounders.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The analysis included random samples of 2510\/10,313 (24.3%) ECS and 7813\/326,552 (2.39%) non-ECS. After accounting for confounding by age, sex, bodyweight within breed-sex, insurance status and veterinary practice group, the ECS had increased odds of 21\/43 (48.85%) disorders at fine-level precision, with highest odds for aural discharge (odds ratio (OR) 14.66, 95% confidence interval (CI): 7.73\u201330.90, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009\u00a00.001) and keratoconjunctivitis sicca (OR 7.64, 95% CI: 4.33\ufeff\u201314.14, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009\u00a00.001) and lowest odds for atopic dermatitis (OR 0.14, 95% CI: 0.05\u20130.31, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009\u00a00.001) and allergy (OR 0.14, 95% CI: 0.06\u20130.28, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009\u00a00.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This study provides evidence for strong predisposition to aural and ocular disorders and protection from hypersensitivity disorders in the ECS. These results can aid dog owners, breeders, and veterinarians to better monitor health in ECS, and promote earlier diagnosis with improved prognosis. Further, the results can help breeding organisations establish key priorities the health-based reforms of the ECS.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40575-023-00136-x","type":"journal-article","created":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T01:02:18Z","timestamp":1705539738000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["English Cocker Spaniels under primary veterinary care in the UK: disorder predispositions and protections"],"prefix":"10.1186","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2800-9990","authenticated-orcid":false,"given":"Karolina S.","family":"Engdahl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave C.","family":"Brodbelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Cameron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David B.","family":"Church","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan G.","family":"O\u2019Neill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,18]]},"reference":[{"issue":"2","key":"136_CR1","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1111\/jbg.12060","volume":"131","author":"M Jansson","year":"2014","unstructured":"Jansson M, Laikre L. 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