{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:51:21Z","timestamp":1770511881261,"version":"3.49.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T00:00:00Z","timestamp":1479427200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Fresenius Kabi Deutschland GmbH"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["ICMx"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s40635-016-0110-5","type":"journal-article","created":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T07:17:22Z","timestamp":1479453442000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Comparison of an automatic analysis and a manual analysis of conjunctival microcirculation in a sheep model of haemorrhagic shock"],"prefix":"10.1186","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9196-730X","authenticated-orcid":false,"given":"Philip-Helge","family":"Arnemann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Hessler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Kampmeier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Morelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo Karel","family":"Van Aken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Westphal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Rehberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Ertmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,11,18]]},"reference":[{"key":"110_CR1","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1513\/AnnalsATS.201509-606OC","volume":"13","author":"VSK Edul","year":"2016","unstructured":"Edul VSK, Ince C, Vazquez AR et al (2016) Similar microcirculatory alterations in patients with normodynamic and hyperdynamic septic shock. Ann Am Thorac Soc 13:240\u2013247. doi: 10.1513\/AnnalsATS.201509-606OC","journal-title":"Ann Am Thorac Soc"},{"key":"110_CR2","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1097\/CCM.0b013e31823dae59","volume":"40","author":"VSK Edul","year":"2012","unstructured":"Edul VSK, Enrico C, Laviolle B et al (2012) Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock. Crit Care Med 40:1443\u20131448. doi: 10.1097\/CCM.0b013e31823dae59","journal-title":"Crit Care Med"},{"key":"110_CR3","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.annemergmed.2006.08.021","volume":"49","author":"S Trzeciak","year":"2007","unstructured":"Trzeciak S, Dellinger RP, Parrillo JE et al (2007) Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival. Ann Emerg Med 49:88\u201398. doi: 10.1016\/j.annemergmed.2006.08.021 , 98.e1\u20132","journal-title":"Ann Emerg Med"},{"key":"110_CR4","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1097\/01.CCM.0000138558.16257.3F","volume":"32","author":"Y Sakr","year":"2004","unstructured":"Sakr Y, Dubois M-J, De Backer D et al (2004) Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 32:1825\u20131831","journal-title":"Crit Care Med"},{"key":"110_CR5","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1097\/CCM.0000000000000553","volume":"43","author":"NAR Vellinga","year":"2015","unstructured":"Vellinga NAR, Boerma EC, Koopmans M et al (2015) International study on microcirculatory shock occurrence in acutely ill patients. Crit Care Med 43:48\u201356. doi: 10.1097\/CCM.0000000000000553","journal-title":"Crit Care Med"},{"key":"110_CR6","doi-asserted-by":"crossref","first-page":"15101","DOI":"10.1364\/OE.15.015101","volume":"15","author":"PT Goedhart","year":"2007","unstructured":"Goedhart PT, Khalilzada M, Bezemer R et al (2007) Sidestream dark field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation. Opt Express 15:15101\u201315114","journal-title":"Opt Express"},{"key":"110_CR7","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s40635-015-0040-7","volume":"3","author":"G Aykut","year":"2015","unstructured":"Aykut G, Veenstra G, Scorcella C et al (2015) Cytocam-IDF (incident dark field illumination) imaging for bedside monitoring of the microcirculation. Intensive Care Med Exp 3:40. doi: 10.1186\/s40635-015-0040-7","journal-title":"Intensive Care Med Exp"},{"key":"110_CR8","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1186\/s13054-015-1106-3","volume":"19","author":"S Tanaka","year":"2015","unstructured":"Tanaka S, Harrois A, Nicola\u00ef C et al (2015) Qualitative real-time analysis by nurses of sublingual microcirculation in intensive care unit: the MICRONURSE study. Crit Care 19:388. doi: 10.1186\/s13054-015-1106-3","journal-title":"Crit Care"},{"issue":"Suppl 3","key":"110_CR9","doi-asserted-by":"publisher","first-page":"S8","DOI":"10.1186\/cc14726","volume":"19","author":"C Ince","year":"2015","unstructured":"Ince C (2015) Hemodynamic coherence and the rationale for monitoring the microcirculation. Crit Care 19(Suppl 3):S8. doi: 10.1186\/cc14726","journal-title":"Crit Care"},{"key":"110_CR10","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1097\/MCC.0000000000000196","volume":"21","author":"VS Kanoore Edul","year":"2015","unstructured":"Kanoore Edul VS, Ince C, Dubin A (2015) What is microcirculatory shock? Curr Opin Crit Care 21:245\u2013252. doi: 10.1097\/MCC.0000000000000196","journal-title":"Curr Opin Crit Care"},{"key":"110_CR11","doi-asserted-by":"crossref","unstructured":"De Backer D, Hollenberg S, Boerma C, et al. (2007) How to evaluate the microcirculation: report of a round table conference. In: Crit Care. p R101","DOI":"10.1186\/cc6118"},{"key":"110_CR12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3181\/00379727-91-22160","volume":"91","author":"SL Hansard","year":"1956","unstructured":"Hansard SL (1956) Residual organ blood volume of cattle, sheep and swine. Proc Soc Exp Biol Med 91:31\u201334","journal-title":"Proc Soc Exp Biol Med"},{"key":"110_CR13","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1016\/j.jcrc.2013.06.015","volume":"28","author":"MJ Massey","year":"2013","unstructured":"Massey MJ, Larochelle E, Najarro G et al (2013) The microcirculation image quality score: development and preliminary evaluation of a proposed approach to grading quality of image acquisition for bedside videomicroscopy. J Crit Care 28:913\u2013917. doi: 10.1016\/j.jcrc.2013.06.015","journal-title":"J Crit Care"},{"key":"110_CR14","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1007\/s11517-008-0349-4","volume":"46","author":"JGG Dobbe","year":"2008","unstructured":"Dobbe JGG, Streekstra GJ, Atasever B et al (2008) Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis. Med Biol Eng Comput 46:659\u2013670. doi: 10.1007\/s11517-008-0349-4","journal-title":"Med Biol Eng Comput"},{"key":"110_CR15","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1191\/026921598672178340","volume":"12","author":"G Rankin","year":"1998","unstructured":"Rankin G, Stokes M (1998) Reliability of assessment tools in rehabilitation: an illustration of appropriate statistical analyses. Clin Rehabil 12:187\u2013199","journal-title":"Clin Rehabil"},{"key":"110_CR16","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1037\/1040-3590.6.4.284","volume":"6","author":"DV Cicchetti","year":"1994","unstructured":"Cicchetti DV (1994) Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology. Psychol Assess 6:284\u2013290. doi: 10.1037\/1040-3590.6.4.284","journal-title":"Psychol Assess"},{"key":"110_CR17","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","volume":"1","author":"JM Bland","year":"1986","unstructured":"Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307\u2013310","journal-title":"Lancet"},{"key":"110_CR18","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.injury.2015.10.075","volume":"47","author":"R Gonz\u00e1lez","year":"2016","unstructured":"Gonz\u00e1lez R, Urbano J, L\u00f3pez J et al (2016) Microcirculatory alterations during haemorrhagic shock and after resuscitation in a paediatric animal model. Injury 47:335\u2013341. doi: 10.1016\/j.injury.2015.10.075","journal-title":"Injury"},{"key":"110_CR19","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1097\/CCM.0000000000000223","volume":"42","author":"G Tachon","year":"2014","unstructured":"Tachon G, Harrois A, Tanaka S et al (2014) Microcirculatory alterations in traumatic hemorrhagic shock. Crit Care Med 42:1433\u20131441. doi: 10.1097\/CCM.0000000000000223","journal-title":"Crit Care Med"},{"key":"110_CR20","doi-asserted-by":"publisher","first-page":"R601","DOI":"10.1186\/cc3809","volume":"9","author":"EC Boerma","year":"2005","unstructured":"Boerma EC, Mathura KR, van der Voort PHJ et al (2005) Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study. Crit Care 9:R601\u2013R606. doi: 10.1186\/cc3809","journal-title":"Crit Care"},{"key":"110_CR21","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1097\/SHK.0000000000000508","volume":"45","author":"L Yin","year":"2016","unstructured":"Yin L, Yang Z, Yu H et al (2016) Changes in sublingual microcirculation is closely related with that of bulbar conjunctival microcirculation in a Rat model of cardiac arrest. Shock 45:428\u2013433. doi: 10.1097\/SHK.0000000000000508","journal-title":"Shock"},{"key":"110_CR22","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1007\/s10877-015-9708-5","volume":"29","author":"HA Elteren van","year":"2015","unstructured":"van Elteren HA, Ince C, Tibboel D et al (2015) Cutaneous microcirculation in preterm neonates: comparison between sidestream dark field (SDF) and incident dark field (IDF) imaging. J Clin Monit Comput 29:543\u2013548. doi: 10.1007\/s10877-015-9708-5","journal-title":"J Clin Monit Comput"},{"key":"110_CR23","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s12880-015-0078-8","volume":"16","author":"E Gilbert-Kawai","year":"2016","unstructured":"Gilbert-Kawai E, Coppel J, Bountziouka V et al (2016) A comparison of the quality of image acquisition between the incident dark field and sidestream dark field video-microscopes. BMC Med Imaging 16:10. doi: 10.1186\/s12880-015-0078-8","journal-title":"BMC Med Imaging"}],"container-title":["Intensive Care Medicine Experimental"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40635-016-0110-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s40635-016-0110-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40635-016-0110-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T23:56:40Z","timestamp":1498348600000},"score":1,"resource":{"primary":{"URL":"http:\/\/icm-experimental.springeropen.com\/articles\/10.1186\/s40635-016-0110-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,18]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["110"],"URL":"https:\/\/doi.org\/10.1186\/s40635-016-0110-5","relation":{},"ISSN":["2197-425X"],"issn-type":[{"value":"2197-425X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,18]]},"article-number":"37"}}