{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T05:28:28Z","timestamp":1786339708944,"version":"build-2736575974"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012190","name":"Ministry of Science and Higher Education of the Russian Federation","doi-asserted-by":"publisher","award":["124020500028-4, FSNF-2025-0013"],"award-info":[{"award-number":["124020500028-4, FSNF-2025-0013"]}],"id":[{"id":"10.13039\/501100012190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bioresour. Bioprocess."],"DOI":"10.1186\/s40643-026-01102-8","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T04:43:34Z","timestamp":1786337014000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Improvement of biosurfactant production by Rhodococcus ruber IEGM 231 grown on waste cooking oil, their emulsifying activity and antioxidant potential"],"prefix":"10.1186","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9165-8363","authenticated-orcid":false,"given":"Maria S.","family":"Kuyukina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasiia V.","family":"Krivoruchko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina B.","family":"Ivshina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"issue":"1","key":"1102_CR1","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/s12934-023-02128-9","volume":"22","author":"M Andreolli","year":"2023","unstructured":"Andreolli M, Villanova V, Zanzoni S et al (2023) Characterization of trehalolipid biosurfactant produced by the novel marine strain Rhodococcus sp. SP1d and its potential for environmental applications. Microb Cell Fact 22(1):126. https:\/\/doi.org\/10.1186\/s12934-023-02128-9","journal-title":"Microb Cell Fact"},{"key":"1102_CR2","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1007\/s11743-013-1466-0","volume":"16","author":"RD Ashby","year":"2013","unstructured":"Ashby RD, McAloon AJ, Solaiman DKY et al (2013) A process model for approximating the production costs of the fermentative synthesis of sophorolipids. J Surfact Deterg 16:683\u2013691. https:\/\/doi.org\/10.1007\/s11743-013-1466-0","journal-title":"J Surfact Deterg"},{"key":"1102_CR3","doi-asserted-by":"publisher","first-page":"103214","DOI":"10.1016\/j.bcab.2024.103214","volume":"58","author":"D Brahma","year":"2024","unstructured":"Brahma D, Sarker A, Kulavi S, Dutta D (2024) Valorization and kinetic modeling of biosurfactant produced by Kocuria marina DAGII: substitute for chemical surfactant. Biocatal Agric Biotechnol 58:103214. https:\/\/doi.org\/10.1016\/j.bcab.2024.103214","journal-title":"Biocatal Agric Biotechnol"},{"issue":"15","key":"1102_CR4","doi-asserted-by":"publisher","first-page":"14934","DOI":"10.1007\/s11356-018-1691-1","volume":"25","author":"C Chen","year":"2018","unstructured":"Chen C, Sun N, Li D et al (2018) Optimization and characterization of biosurfactant production from kitchen waste oil using Pseudomonas aeruginosa. Environ Sci Pollut Res 25(15):14934\u201314943. https:\/\/doi.org\/10.1007\/s11356-018-1691-1","journal-title":"Environ Sci Pollut Res"},{"key":"1102_CR5","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1046\/j.1365-2672.2002.01774.x","volume":"93","author":"N Christofi","year":"2001","unstructured":"Christofi N, Ivshina IB (2001) Microbial surfactants and their use in field studies of soil remediation. J Appl Microbiol 93:915\u2013929. https:\/\/doi.org\/10.1046\/j.1365-2672.2002.01774.x","journal-title":"J Appl Microbiol"},{"issue":"6","key":"1102_CR6","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1002\/ejlt.200900162","volume":"112","author":"A Franzetti","year":"2010","unstructured":"Franzetti A, Gandolfi I, Bestetti G et al (2010) Production and applications of trehalose lipid biosurfactants. Eur J Lipid Sci Technol 112(6):617\u2013627. https:\/\/doi.org\/10.1002\/ejlt.200900162","journal-title":"Eur J Lipid Sci Technol"},{"key":"1102_CR7","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1007\/s10517-020-04912-8","volume":"169","author":"SV Gein","year":"2020","unstructured":"Gein SV, Kochina OA, Kuyukina MS et al (2020) Effects of monoacyltrehalose fraction of Rhodococcus biosurfactant on the innate and adaptive immunity parameters in vivo. Bull Exp Biol Med 169:474\u2013477. https:\/\/doi.org\/10.1007\/s10517-020-04912-8","journal-title":"Bull Exp Biol Med"},{"key":"1102_CR8","doi-asserted-by":"publisher","first-page":"974","DOI":"10.3390\/pathogens10080974","volume":"10","author":"IB Ivshina","year":"2021","unstructured":"Ivshina IB, Kuyukina MS, Krivoruchko AV, Tyumina EA (2021) Responses to ecopollutants and pathogenization risks of saprotrophic Rhodococcus species. Pathogens 10:974. https:\/\/doi.org\/10.3390\/pathogens10080974","journal-title":"Pathogens"},{"key":"1102_CR9","doi-asserted-by":"publisher","first-page":"122394","DOI":"10.1016\/j.biortech.2019.122394","volume":"298","author":"J Jiang","year":"2020","unstructured":"Jiang J, Zu Y, Li X et al (2020) Recent progress towards industrial rhamnolipids fermentation: process optimization and foam control. Biores Technol 298:122394. https:\/\/doi.org\/10.1016\/j.biortech.2019.122394","journal-title":"Biores Technol"},{"key":"1102_CR10","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/0168-1656(90)90074-L","volume":"13","author":"J-S Kim","year":"1990","unstructured":"Kim J-S, Powalla M, Lang S et al (1990) Microbial glycolipid production under nitrogen limitation and resting cell conditions. J Biotechnol 13:257\u2013266. https:\/\/doi.org\/10.1016\/0168-1656(90)90074-L","journal-title":"J Biotechnol"},{"key":"1102_CR11","doi-asserted-by":"publisher","first-page":"595","DOI":"10.3390\/molecules30030595","volume":"30","author":"IE K\u0142osowska-Chomiczewska","year":"2025","unstructured":"K\u0142osowska-Chomiczewska IE, Burakowska G, Zmuda-Trzebiatowska P et al (2025) High internal phase oil-in-water emulsions stabilised by cost-effective rhamnolipid\/alginate biocomplexes. Molecules 30:595. https:\/\/doi.org\/10.3390\/molecules30030595","journal-title":"Molecules"},{"issue":"9","key":"1102_CR12","doi-asserted-by":"publisher","first-page":"2088","DOI":"10.3390\/molecules29092088","volume":"29","author":"D Kuczy\u0144ska-Wi\u015bnik","year":"2024","unstructured":"Kuczy\u0144ska-Wi\u015bnik D, Stojowska-Sw\u0119drzy\u0144ska K, Laskowska E (2024) Intracellular protective functions and therapeutical potential of trehalose. Molecules 29(9):2088. https:\/\/doi.org\/10.3390\/molecules29092088","journal-title":"Molecules"},{"key":"1102_CR13","doi-asserted-by":"publisher","unstructured":"Kuyukina MS, Ivshina IB (2019) Production of trehalolipid biosurfactants by Rhodococcus. In: Alvarez HM (ed) Biology of Rhodococcus. Microbiology Monographs, vol 16. Springer Nature, pp 271\u2013298. https:\/\/doi.org\/10.1007\/978-3-030-11461-9_10","DOI":"10.1007\/978-3-030-11461-9_10"},{"key":"1102_CR16","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/s0167-7012(01)00259-7","volume":"46","author":"MS Kuyukina","year":"2001","unstructured":"Kuyukina MS, Ivshina IB, Philp JC et al (2001) Recovery of Rhodococcus biosurfactants using methyl-tertiary butyl ether extraction. J Microbiol Methods 46:149\u2013156. https:\/\/doi.org\/10.1016\/s0167-7012(01)00259-7","journal-title":"J Microbiol Methods"},{"key":"1102_CR14","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s13568-016-0186-z","volume":"6","author":"MS Kuyukina","year":"2016","unstructured":"Kuyukina MS, Ivshina IB, Korshunova IO et al (2016) Diverse effects of a biosurfactant from Rhodococcus ruber IEGM 231 on the adhesion of resting and growing bacteria to polystyrene. AMB Express 6:14. https:\/\/doi.org\/10.1186\/s13568-016-0186-z","journal-title":"AMB Express"},{"key":"1102_CR15","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1134\/S0003683820030072","volume":"56","author":"MS Kuyukina","year":"2020","unstructured":"Kuyukina MS, Kochina OA, Gein SV et al (2020) Mechanisms of immunomodulatory and membranotropic activity of trehalolipid biosurfactants. Appl Biochem Microbiol 56:245\u2013255. https:\/\/doi.org\/10.1134\/S0003683820030072","journal-title":"Appl Biochem Microbiol"},{"key":"1102_CR17","doi-asserted-by":"publisher","first-page":"136","DOI":"10.3390\/fermentation7030136","volume":"7","author":"J Liepins","year":"2021","unstructured":"Liepins J, Balina K, Soloha R et al (2021) Glycolipid biosurfactant production from waste cooking oils by yeast: review of substrates, producers and products. Fermentation 7:136. https:\/\/doi.org\/10.3390\/fermentation7030136","journal-title":"Fermentation"},{"issue":"4","key":"1102_CR18","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2013\u2206\u2206CT method. Methods 25(4):402\u2013408. https:\/\/doi.org\/10.1006\/meth.2001.1262","journal-title":"Methods"},{"key":"1102_CR19","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1007\/s00300-015-1717-9","volume":"38","author":"R Malavenda","year":"2015","unstructured":"Malavenda R, Rizzo C, Michaud L et al (2015) Biosurfactant production by Arctic and Antarctic bacteria growing on hydrocarbons. Polar Biol 38:1565\u20131574. https:\/\/doi.org\/10.1007\/s00300-015-1717-9","journal-title":"Polar Biol"},{"key":"1102_CR20","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.tibtech.2006.09.005","volume":"24","author":"S Mukherjee","year":"2006","unstructured":"Mukherjee S, Das P, Sen R (2006) Towards commercial production of microbial surfactants. Trends Biotechnol 24:509\u2013515. https:\/\/doi.org\/10.1016\/j.tibtech.2006.09.005","journal-title":"Trends Biotechnol"},{"issue":"3","key":"1102_CR21","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1002\/fsn3.880","volume":"7","author":"Y Niu","year":"2019","unstructured":"Niu Y, Wu J, Wang W, Chen Q (2019) Production and characterization of a new glycolipid, mannosylerythritol lipid, from waste cooking oil biotransformation by Pseudozyma aphidis ZJUDM34. Food Sci Nutr 7(3):937\u2013948. https:\/\/doi.org\/10.1002\/fsn3.880","journal-title":"Food Sci Nutr"},{"issue":"2\u20133","key":"1102_CR24","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1007\/s00253-002-1018-4","volume":"59","author":"JC Philp","year":"2002","unstructured":"Philp JC, Kuyukina MS, Ivshina IB et al (2002) Alkanotrophic Rhodococcus ruber as a biosurfactant producer. Appl Microbiol Biotechnol 59(2\u20133):318\u2013324. https:\/\/doi.org\/10.1007\/s00253-002-1018-4","journal-title":"Appl Microbiol Biotechnol"},{"key":"1102_CR23","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1023\/B:ABIM.0000040670.33787.5f","volume":"40","author":"TP Pirog","year":"2004","unstructured":"Pirog TP, Shevchuk TA, Voloshina IN et al (2004) Production of surfactants by Rhodococcus erythropolis strain EK-1, grown on hydrophilic and hydrophobic substrates. Appl Biochem Microbiol 40:470\u2013475. https:\/\/doi.org\/10.1023\/B:ABIM.0000040670.33787.5f","journal-title":"Appl Biochem Microbiol"},{"key":"1102_CR22","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.fbp.2013.01.001","volume":"91","author":"T Pirog","year":"2013","unstructured":"Pirog T, Sofilkanych A, Konon A et al (2013) Intensification of surfactants\u2019 synthesis by Rhodococcus erythropolis IMV Ac-5017, Acinetobacter calcoaceticus IMV B-7241 and Nocardia vaccinii K-8 on fried oil and glycerol containing medium. Food Bioprod Process 91:149\u2013157. https:\/\/doi.org\/10.1016\/j.fbp.2013.01.001","journal-title":"Food Bioprod Process"},{"issue":"4","key":"1102_CR25","doi-asserted-by":"publisher","first-page":"513","DOI":"10.3390\/foods13040513","volume":"13","author":"C Quezada","year":"2024","unstructured":"Quezada C, Urra M, Mella C et al (2024) Plant-based oil-in-water food emulsions: exploring the influence of different formulations on their physicochemical properties. Foods 13(4):513. https:\/\/doi.org\/10.3390\/foods13040513","journal-title":"Foods"},{"key":"1102_CR26","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1007\/BF00132166","volume":"5","author":"E Ristau","year":"1983","unstructured":"Ristau E, Wagner F (1983) Formation of novel anionic trehalose-tetraesters from Rhodococcus erythropolis under growth limiting condition. Biotechnol Lett 5:95\u2013100. https:\/\/doi.org\/10.1007\/BF00132166","journal-title":"Biotechnol Lett"},{"issue":"1","key":"1102_CR27","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1128\/CMR.18.1.81-101.2005","volume":"18","author":"K Takayama","year":"2005","unstructured":"Takayama K, Wang C, Besra GS (2005) Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. Clin Microbiol Rev 18(1):81\u2013101. https:\/\/doi.org\/10.1128\/CMR.18.1.81-101.2005","journal-title":"Clin Microbiol Rev"},{"key":"1102_CR28","doi-asserted-by":"publisher","first-page":"308","DOI":"10.3390\/biom15020308","volume":"15","author":"M Tancredi","year":"2025","unstructured":"Tancredi M, Carandente Coscia C, Russo Krauss I, D\u2019Errico G (2025) Antioxidant properties of biosurfactants: multifunctional biomolecules with added value in formulation chemistry. Biomolecules 15:308. https:\/\/doi.org\/10.3390\/biom15020308","journal-title":"Biomolecules"},{"issue":"9","key":"1102_CR29","doi-asserted-by":"publisher","first-page":"e2300757","DOI":"10.1002\/jobm.202300757","volume":"64","author":"A Thundiparambil Venu","year":"2024","unstructured":"Thundiparambil Venu A, Vijayan J, Ammanamveetil MHA, Kottekkattu Padinchati K (2024) An insightful overview of microbial biosurfactant: a promising next-generation biomolecule for sustainable future. J Basic Microbiol 64(9):e2300757. https:\/\/doi.org\/10.1002\/jobm.202300757","journal-title":"J Basic Microbiol"},{"key":"1102_CR30","doi-asserted-by":"publisher","first-page":"1703","DOI":"10.1111\/j.1365-2672.2007.03680.x","volume":"104","author":"B Tuleva","year":"2008","unstructured":"Tuleva B, Christova N, Cohen R et al (2008) Production and structural elucidation of trehalose tetraesters (biosurfactants) from a novel alkanothrophic Rhodococcus wratislaviensis strain. J App Microbiol 104:1703\u20131710. https:\/\/doi.org\/10.1111\/j.1365-2672.2007.03680.x","journal-title":"J App Microbiol"},{"issue":"3","key":"1102_CR32","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1111\/jam.12287","volume":"115","author":"DA White","year":"2013","unstructured":"White DA, Hird LC, Ali ST (2013) Production and characterization of a trehalolipid biosurfactant produced by the novel marine bacterium Rhodococcus sp., strain PML026. J Appl Microbiol 115(3):744\u2013755. https:\/\/doi.org\/10.1111\/jam.12287","journal-title":"J Appl Microbiol"}],"container-title":["Bioresources and Bioprocessing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40643-026-01102-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40643-026-01102-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40643-026-01102-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T04:43:40Z","timestamp":1786337020000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s40643-026-01102-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,10]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1102"],"URL":"https:\/\/doi.org\/10.1186\/s40643-026-01102-8","relation":{},"ISSN":["2197-4365"],"issn-type":[{"value":"2197-4365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,10]]},"assertion":[{"value":"26 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 July 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"110"}}