{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T04:19:10Z","timestamp":1788149950676,"version":"build-2803163510"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100006764","name":"Technische Universit\u00e4t Berlin","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006764","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bioresour. Bioprocess."],"DOI":"10.1186\/s40643-026-01120-6","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T04:07:52Z","timestamp":1788149272000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cell-retention for lipid production in continuous Schizochytrium limacinum SR21 cultures fed with dark fermentation effluent"],"prefix":"10.1186","volume":"13","author":[{"given":"Simon","family":"T\u00e4uber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonie","family":"Ackermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Schittkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Neubauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6185-2627","authenticated-orcid":false,"given":"Stefan","family":"Junne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"1120_CR1","doi-asserted-by":"publisher","first-page":"125793","DOI":"10.1016\/j.biortech.2021.125793","volume":"341","author":"B Akkoyunlu","year":"2021","unstructured":"Akkoyunlu B, Daly S, Casey E (2021) Membrane bioreactors for the production of value-added products: recent developments, challenges and perspectives. Bioresour Technol 341:125793. https:\/\/doi.org\/10.1016\/j.biortech.2021.125793","journal-title":"Bioresour Technol"},{"key":"1120_CR2","doi-asserted-by":"publisher","first-page":"129481","DOI":"10.1016\/j.cej.2021.129481","volume":"418","author":"MB Asif","year":"2021","unstructured":"Asif MB, Zhang Z (2021) Ceramic membrane technology for water and wastewater treatment: a critical review of performance, full-scale applications, membrane fouling and prospects. Chem Eng J 418:129481. https:\/\/doi.org\/10.1016\/j.cej.2021.129481","journal-title":"Chem Eng J"},{"key":"1120_CR3","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1016\/j.spc.2021.04.033","volume":"27","author":"L Bartek","year":"2021","unstructured":"Bartek L, Strid I, Junne S et al (2021) Life cycle assessment of fish oil substitute produced by microalgae using food waste. Sustain Prod Consum 27:2002\u20132021. https:\/\/doi.org\/10.1016\/j.spc.2021.04.033","journal-title":"Sustainable Prod Consum"},{"key":"1120_CR4","doi-asserted-by":"publisher","first-page":"107687","DOI":"10.1016\/j.bej.2020.107687","volume":"161","author":"A Burniol-Figols","year":"2020","unstructured":"Burniol-Figols A, Pinelo M, Skiadas IV, Gavala HN (2020) Enhancing polyhydroxyalkanoate productivity with cell-retention membrane bioreactors. Biochem Eng J 161:107687. https:\/\/doi.org\/10.1016\/j.bej.2020.107687","journal-title":"Biochem Eng J"},{"key":"1120_CR6","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.apenergy.2019.03.058","volume":"241","author":"A Chalima","year":"2019","unstructured":"Chalima A, Hatzidaki A, Karnaouri A, Topakas E (2019) Integration of a dark fermentation effluent in a microalgal-based biorefinery for the production of high-added value omega-3 fatty acids. Appl Energy 241:130\u2013138. https:\/\/doi.org\/10.1016\/j.apenergy.2019.03.058","journal-title":"Appl Energy"},{"key":"1120_CR7","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1016\/j.renene.2020.01.041","volume":"152","author":"A Chalima","year":"2020","unstructured":"Chalima A, Taxeidis G, Topakas E (2020) Optimization of the production of docosahexaenoic fatty acid by the heterotrophic microalga Crypthecodinium cohnii utilizing a dark fermentation effluent. Renew Energy 152:102\u2013109. https:\/\/doi.org\/10.1016\/j.renene.2020.01.041","journal-title":"Renewable Energy"},{"key":"1120_CR5","doi-asserted-by":"publisher","first-page":"fnab054","DOI":"10.1093\/femsle\/fnab054","volume":"368","author":"A Chalima","year":"2021","unstructured":"Chalima A, Castro LFD, Burgstaller L et al (2021) Waste-derived volatile fatty acids as carbon source for added-value fermentation approaches. FEMS Microbiol Lett 368:fnab054. https:\/\/doi.org\/10.1093\/femsle\/fnab054","journal-title":"FEMS Microbiol Lett"},{"key":"1120_CR8","doi-asserted-by":"publisher","first-page":"3222","DOI":"10.3390\/en12173222","volume":"12","author":"W Cieciura-W\u0142och","year":"2019","unstructured":"Cieciura-W\u0142och W, Binczarski M, Tomaszewska J et al (2019) The use of acidic hydrolysates after furfural production from sugar waste biomass as a fermentation medium in the biotechnological production of hydrogen. Energies 12:3222. https:\/\/doi.org\/10.3390\/en12173222","journal-title":"Energies"},{"key":"1120_CR9","doi-asserted-by":"publisher","first-page":"1606","DOI":"10.3390\/pr12081606","volume":"12","author":"W Cieciura-W\u0142och","year":"2024","unstructured":"Cieciura-W\u0142och W, Borowski S, Januszewicz B, Doma\u0144ski J (2024) Effects of sugar beet pulp pretreatment methods on hydrogen production by dark fermentation. Processes 12:1606. https:\/\/doi.org\/10.3390\/pr12081606","journal-title":"Processes"},{"key":"1120_CR10","doi-asserted-by":"publisher","first-page":"4483","DOI":"10.1007\/s13762-022-04740-5","volume":"20","author":"P Contreras","year":"2023","unstructured":"Contreras P, Oviedo C (2023) Potential and future perspectives of thraustochytrids in bioremediation. Int J Environ Sci Technol 20:4483\u20134498. https:\/\/doi.org\/10.1007\/s13762-022-04740-5","journal-title":"Int J Environ Sci Technol"},{"key":"1120_CR11","doi-asserted-by":"publisher","first-page":"703","DOI":"10.3390\/membranes12070703","volume":"12","author":"SF Corsino","year":"2022","unstructured":"Corsino SF, Di Bella G, Traina F et al (2022) Membrane fouling mitigation in MBR via the feast\u2013famine strategy to enhance PHA production by activated sludge. Membranes 12:703. https:\/\/doi.org\/10.3390\/membranes12070703","journal-title":"Membranes"},{"key":"1120_CR12","doi-asserted-by":"publisher","first-page":"114328","DOI":"10.1016\/j.rser.2024.114328","volume":"195","author":"RA Dar","year":"2024","unstructured":"Dar RA, Tsui T-H, Zhang L et al (2024) Fermentation of organic wastes through oleaginous microorganisms for lipid production - Challenges and opportunities. Renew Sustain Energy Rev 195:114328. https:\/\/doi.org\/10.1016\/j.rser.2024.114328","journal-title":"Renew Sustain Energy Rev"},{"key":"1120_CR13","doi-asserted-by":"publisher","first-page":"2421","DOI":"10.3390\/nu13072421","volume":"13","author":"I Djuricic","year":"2021","unstructured":"Djuricic I, Calder PC (2021) Beneficial outcomes of omega-6 and omega-3 polyunsaturated fatty acids on human health: an update for 2021. Nutrients 13:2421. https:\/\/doi.org\/10.3390\/nu13072421","journal-title":"Nutrients"},{"key":"1120_CR14","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1007\/s10295-018-2081-x","volume":"45","author":"R Fu","year":"2018","unstructured":"Fu R, Fei Q, Shang L et al (2018) Enhanced microbial lipid production by Cryptococcus albidus in the high-cell-density continuous cultivation with membrane cell recycling and two-stage nutrient limitation. J Ind Microbiol Biotechnol 45:1045\u20131051. https:\/\/doi.org\/10.1007\/s10295-018-2081-x","journal-title":"J Ind Microbiol Biotechnol"},{"key":"1120_CR15","doi-asserted-by":"publisher","first-page":"19470","DOI":"10.1038\/s41598-019-55902-4","volume":"9","author":"TMB Heggeset","year":"2019","unstructured":"Heggeset TMB, Ertesv\u00e5g H, Liu B et al (2019) Lipid and DHA-production in Aurantiochytrium sp. \u2013 Responses to nitrogen starvation and oxygen limitation revealed by analyses of production kinetics and global transcriptomes. Sci Rep 9:19470. https:\/\/doi.org\/10.1038\/s41598-019-55902-4","journal-title":"Sci Rep"},{"key":"1120_CR16","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1007\/s00449-015-1452-1","volume":"38","author":"X-C Hu","year":"2015","unstructured":"Hu X-C, Ren L-J, Chen S-L et al (2015) The roles of different salts and a novel osmotic pressure control strategy for improvement of DHA production by Schizochytrium sp. Bioprocess Biosystem Eng 38:2129\u20132136. https:\/\/doi.org\/10.1007\/s00449-015-1452-1","journal-title":"Bioprocess Biosystem Eng"},{"key":"1120_CR17","doi-asserted-by":"publisher","first-page":"711971","DOI":"10.3389\/fceng.2021.711971","volume":"3","author":"E Janesch","year":"2021","unstructured":"Janesch E, Pereira J, Neubauer P, Junne S (2021) Phase separation in anaerobic digestion: a potential for easier process combination? Front Chem Eng 3:711971. https:\/\/doi.org\/10.3389\/fceng.2021.711971","journal-title":"Front Chem Eng"},{"key":"1120_CR18","doi-asserted-by":"publisher","unstructured":"Junne S, Cziommer J, T\u00e4uber S, Neubauer P (2021) 8 From cellulose to lipids. In: Biorefinery: from biomass to chemicals and fuels. De Gruyter, pp 229\u2013264. https:\/\/doi.org\/10.1515\/9783110705386-009","DOI":"10.1515\/9783110705386-009"},{"key":"1120_CR19","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3389\/fmars.2020.00057","volume":"7","author":"K Katerina","year":"2020","unstructured":"Katerina K, Berge GM, Turid M et al (2020) Microalgal Schizochytrium limacinum biomass improves growth and filet quality when used long-term as a replacement for fish oil, in Modern Salmon Diets. Front Mar Sci 7:57. https:\/\/doi.org\/10.3389\/fmars.2020.00057","journal-title":"Front Mar Sci"},{"key":"1120_CR20","doi-asserted-by":"publisher","first-page":"1757","DOI":"10.3390\/en16041757","volume":"16","author":"A Koruyucu","year":"2023","unstructured":"Koruyucu A, Blums K, Peest T et al (2023) High-cell-density yeast oil production with diluted substrates imitating microalgae hydrolysate using a membrane bioreactor. Energies 16:1757. https:\/\/doi.org\/10.3390\/en16041757","journal-title":"Energies"},{"issue":"13","key":"1120_CR21","doi-asserted-by":"publisher","first-page":"6541","DOI":"10.3390\/app12136541","volume":"12","author":"E Krikigianni","year":"2022","unstructured":"Krikigianni E, Matsakas L, Rova U et al (2022) Investigating the bioconversion potential of volatile fatty acids: use of oleaginous yeasts Rhodosporidium toruloides and Cryptococcus curvatus towards the sustainable production of biodiesel and odd-chain fatty acids. Appl Sci (Switzerland) 12(13):6541. https:\/\/doi.org\/10.3390\/app12136541","journal-title":"Appl Sci (Switzerland)"},{"key":"1120_CR22","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1007\/s11274-025-04268-z","volume":"41","author":"J Liu","year":"2025","unstructured":"Liu J, Feng X, Wang S et al (2025) Metabolic regulation strategies for enhancing microbial docosahexaenoic acid production by Schizochytrium sp. World J Microb Biotechnol 41:142. https:\/\/doi.org\/10.1007\/s11274-025-04268-z","journal-title":"World J Microb Biotechnol"},{"key":"1120_CR23","doi-asserted-by":"publisher","first-page":"106803","DOI":"10.1016\/j.biombioe.2023.106803","volume":"173","author":"M Longis","year":"2023","unstructured":"Longis M, Pereira JC, H\u00f6gl TH et al (2023) Plug-flow anaerobic digestion with multi-position sensors: the value of gradient measurement for process monitoring. Biomass Bioenergy 173:106803. https:\/\/doi.org\/10.1016\/j.biombioe.2023.106803","journal-title":"Biomass Bioenergy"},{"key":"1120_CR24","doi-asserted-by":"publisher","first-page":"121","DOI":"10.3390\/fermentation11030121","volume":"11","author":"Q Lyu","year":"2025","unstructured":"Lyu Q, Dar RA, Baganz F et al (2025) Effects of lignocellulosic biomass-derived hydrolysate inhibitors on cell growth and lipid production during microbial fermentation of oleaginous microorganisms\u2014a review. Fermentation 11:121. https:\/\/doi.org\/10.3390\/fermentation11030121","journal-title":"Fermentation"},{"key":"1120_CR25","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.procbio.2016.11.003","volume":"52","author":"A-M Marb\u00e0-Ard\u00e9bol","year":"2017","unstructured":"Marb\u00e0-Ard\u00e9bol A-M, Emmerich J, Neubauer P, Junne S (2017) Single-cell-based monitoring of fatty acid accumulation in Crypthecodinium cohnii with three-dimensional holographic and in situ microscopy. Process Biochem 52:223\u2013232. https:\/\/doi.org\/10.1016\/j.procbio.2016.11.003","journal-title":"Process Biochem"},{"key":"1120_CR26","doi-asserted-by":"publisher","first-page":"5555","DOI":"10.3390\/en13215555","volume":"13","author":"T Menzel","year":"2020","unstructured":"Menzel T, Neubauer P, Junne S (2020) Role of microbial hydrolysis in anaerobic digestion. Energies 13:5555. https:\/\/doi.org\/10.3390\/en13215555","journal-title":"Energies"},{"key":"1120_CR27","doi-asserted-by":"publisher","DOI":"10.1007\/s13399-023-03958-8","author":"T Menzel","year":"2023","unstructured":"Menzel T, Neubauer P, Junne S (2023a) Effect of bioaugmentation with Paenibacillus spp. and thin slurry recirculation on microbial hydrolysis of maize silage and bedding straw in a plug-flow reactor. Biomass Convers Biorefinery. https:\/\/doi.org\/10.1007\/s13399-023-03958-8","journal-title":"Biomass Convers Biorefinery"},{"key":"1120_CR28","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1186\/s13068-023-02363-7","volume":"16","author":"T Menzel","year":"2023","unstructured":"Menzel T, Neubauer P, Junne S (2023b) Plug-flow hydrolysis with lignocellulosic residues: effect of hydraulic retention time and thin-sludge recirculation. Biotechnol Biofuels Bioprod 16:111. https:\/\/doi.org\/10.1186\/s13068-023-02363-7","journal-title":"Biotechnol Biofuels Bioprod"},{"key":"1120_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jbiotec.2016.10.021","volume":"241","author":"A Meo","year":"2017","unstructured":"Meo A, Priebe XL, Weuster-Botz D (2017) Lipid production with Trichosporon oleaginosus in a membrane bioreactor using microalgae hydrolysate. J Biotechnol 241:1\u201310. https:\/\/doi.org\/10.1016\/j.jbiotec.2016.10.021","journal-title":"J Biotechnol"},{"key":"1120_CR30","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1016\/j.biotechadv.2014.04.007","volume":"32","author":"F Monlau","year":"2014","unstructured":"Monlau F, Sambusiti C, Barakat A et al (2014) Do furanic and phenolic compounds of lignocellulosic and algae biomass hydrolyzate inhibit anaerobic mixed cultures? A comprehensive review. Biotechnol Adv 32:934\u2013951. https:\/\/doi.org\/10.1016\/j.biotechadv.2014.04.007","journal-title":"Biotechnol Adv"},{"key":"1120_CR31","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1038\/s41586-021-03308-6","volume":"591","author":"RL Naylor","year":"2021","unstructured":"Naylor RL, Hardy RW, Buschmann AH et al (2021) A 20-year retrospective review of global aquaculture. Nature 591:551\u2013563. https:\/\/doi.org\/10.1038\/s41586-021-03308-6","journal-title":"Nature"},{"issue":"5","key":"1120_CR34","doi-asserted-by":"publisher","first-page":"694","DOI":"10.3390\/biom10050694","volume":"10","author":"A Patel","year":"2020","unstructured":"Patel A, Rova U, Christakopoulos P, Matsakas L (2020) Assessment of fatty acids profile and omega-3 polyunsaturated fatty acid production by the oleaginous marine thraustochytrid Aurantiochytrium sp. T66 cultivated on volatile fatty acids. Biomolecules 10(5):694. https:\/\/doi.org\/10.3390\/biom10050694","journal-title":"Biomolecules"},{"key":"1120_CR33","doi-asserted-by":"publisher","first-page":"614612","DOI":"10.3389\/fmicb.2021.614612","volume":"12","author":"A Patel","year":"2021","unstructured":"Patel A, Mahboubi A, Horv\u00e1th IS et al (2021) Volatile fatty acids (VFAs) generated by anaerobic digestion serve as feedstock for freshwater and marine oleaginous microorganisms to produce biodiesel and added-value compounds. Front Microbiol 12:614612. https:\/\/doi.org\/10.3389\/fmicb.2021.614612","journal-title":"Front Microbiol"},{"key":"1120_CR32","doi-asserted-by":"publisher","first-page":"135529","DOI":"10.1016\/j.cej.2022.135529","volume":"438","author":"A Patel","year":"2022","unstructured":"Patel A, Krikigianni E, Rova U et al (2022) Bioprocessing of volatile fatty acids by oleaginous freshwater microalgae and their potential for biofuel and protein production. Chem Eng J 438:135529. https:\/\/doi.org\/10.1016\/j.cej.2022.135529","journal-title":"Chem Eng J"},{"key":"1120_CR35","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.cej.2019.02.050","volume":"367","author":"T Paul","year":"2019","unstructured":"Paul T, Baskaran D, Pakshirajan K, Pugazhenthi G (2019) Continuous bioreactor with cell recycle using tubular ceramic membrane for simultaneous wastewater treatment and bio-oil production by oleaginous Rhodococcus opacus. Chem Eng J 367:76\u201385. https:\/\/doi.org\/10.1016\/j.cej.2019.02.050","journal-title":"Chem Eng J"},{"key":"1120_CR36","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/0003-2697(85)90229-5","volume":"148","author":"S Saheki","year":"1985","unstructured":"Saheki S, Takeda A, Shimazu T (1985) Assay of inorganic phosphate in the mild pH range, suitable for measurement of glycogen phosphorylase activity. Anal Biochem 148:277\u2013281. https:\/\/doi.org\/10.1016\/0003-2697(85)90229-5","journal-title":"Anal Biochem"},{"key":"1120_CR37","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1111\/anu.12230","volume":"22","author":"PK Sarker","year":"2016","unstructured":"Sarker PK, Gamble MM, Kelson S, Kapuscinski AR (2016) Nile tilapia (Oreochromis niloticus) show high digestibility of lipid and fatty acids from marine Schizochytrium sp. and of protein and essential amino acids from freshwater Spirulina sp. feed ingredients. Aquacult Nutr 22:109\u2013119. https:\/\/doi.org\/10.1111\/anu.12230","journal-title":"Aquacult Nutr"},{"key":"1120_CR38","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1007\/s00449-019-02073-1","volume":"42","author":"E Sathiyamoorthi","year":"2019","unstructured":"Sathiyamoorthi E, Kumar P, Kim BS (2019) Lipid production by Cryptococcus albidus using biowastes hydrolysed by indigenous microbes. Bioprocess Biosyst Eng 42:687\u2013696. https:\/\/doi.org\/10.1007\/s00449-019-02073-1","journal-title":"Bioprocess Biosystem Eng"},{"key":"1120_CR39","doi-asserted-by":"publisher","first-page":"132010","DOI":"10.1016\/j.biortech.2024.132010","volume":"419","author":"L Schroedter","year":"2025","unstructured":"Schroedter L, Schneider R, Venus J (2025) Transforming waste wood into pure L-(+)-lactic acid: Efficient use of mixed sugar media through cell-recycled continuous fermentation. Bioresour Technol 419:132010. https:\/\/doi.org\/10.1016\/j.biortech.2024.132010","journal-title":"Bioresour Technol"},{"key":"1120_CR40","doi-asserted-by":"publisher","first-page":"104749","DOI":"10.1016\/j.jwpe.2023.104749","volume":"58","author":"M Shafiq","year":"2024","unstructured":"Shafiq M, Zhang BB, Zeb L et al (2024) Integrated biorefinery approach for bioconversion of fish manure to volatile fatty acids and its valorization by Schizochytrium sp. for docosahexaenoic acid, squalene, and carotenoids production. J Water Process Eng 58:104749. https:\/\/doi.org\/10.1016\/j.jwpe.2023.104749","journal-title":"J Water Process Eng"},{"key":"1120_CR41","doi-asserted-by":"publisher","first-page":"127912","DOI":"10.1016\/j.jenvman.2025.127912","volume":"395","author":"S T\u00e4uber","year":"2025","unstructured":"T\u00e4uber S, Janesch E, Neubauer P, Junne S (2025a) An update on valorising dark fermentation effluent through microbial lipid synthesis. J Environ Manage 395:127912. https:\/\/doi.org\/10.1016\/j.jenvman.2025.127912","journal-title":"J Environ Manage"},{"key":"1120_CR42","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s00253-025-13554-7","volume":"109","author":"S T\u00e4uber","year":"2025","unstructured":"T\u00e4uber S, Riedel SL, Junne S (2025b) Polyhydroxyalkanoate production from food residues. Appl Microbiol Biotechnol 109:171. https:\/\/doi.org\/10.1007\/s00253-025-13554-7","journal-title":"Appl Microbiol Biotechnol"},{"key":"1120_CR43","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s44315-024-00012-8","volume":"1","author":"L Tian","year":"2024","unstructured":"Tian L, Chi G, Lin S et al (2024) Marine microorganisms: natural factories for polyunsaturated fatty acid production. Blue Biotechnol 1:15. https:\/\/doi.org\/10.1186\/s44315-024-00012-8","journal-title":"Blue Biotechnol"},{"key":"1120_CR45","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1111\/j.1365-2109.2008.02150.x","volume":"41","author":"DR Tocher","year":"2010","unstructured":"Tocher DR (2010) Fatty acid requirements in ontogeny of marine and freshwater fish. Aquac Res 41:717\u2013732. https:\/\/doi.org\/10.1111\/j.1365-2109.2008.02150.x","journal-title":"Aquac Res"},{"key":"1120_CR44","doi-asserted-by":"publisher","first-page":"89","DOI":"10.3390\/nu11010089","volume":"11","author":"D Tocher","year":"2019","unstructured":"Tocher D, Betancor M, Sprague M et al (2019) Omega-3 long-chain polyunsaturated fatty acids, EPA and DHA: bridging the gap between supply and demand. Nutrients 11:89. https:\/\/doi.org\/10.3390\/nu11010089","journal-title":"Nutrients"},{"key":"1120_CR46","doi-asserted-by":"publisher","first-page":"131773","DOI":"10.1016\/j.biortech.2024.131773","volume":"417","author":"A Tsirigka","year":"2025","unstructured":"Tsirigka A, Aggeli A, Theodosiou E et al (2025) Model-based study of Yarrowia lipolytica cultivation on crude glycerol under different fermentation modes: development of a membrane bioreactor process. Bioresour Technol 417:131773. https:\/\/doi.org\/10.1016\/j.biortech.2024.131773","journal-title":"Bioresour Technol"},{"key":"1120_CR47","doi-asserted-by":"publisher","first-page":"118854","DOI":"10.1016\/j.seppur.2021.118854","volume":"272","author":"JM Wang","year":"2021","unstructured":"Wang JM, Jin QQ, Zhang YY et al (2021) Reducing the membrane fouling in cross-flow filtration using a facile fluidic oscillator. Sep Purif Technol 272:118854. https:\/\/doi.org\/10.1016\/j.seppur.2021.118854","journal-title":"Sep Purif Technol"},{"key":"1120_CR48","doi-asserted-by":"publisher","first-page":"2100470","DOI":"10.1002\/biot.202100470","volume":"17","author":"L Wang","year":"2022","unstructured":"Wang L, Zhang Z, Wang Y et al (2022) Assessing the potential of Schizochytrium sp. HX-308 for microbial lipids production from corn stover hydrolysate. Biotechnol J 17:2100470. https:\/\/doi.org\/10.1002\/biot.202100470","journal-title":"Biotechnol J"},{"key":"1120_CR49","doi-asserted-by":"publisher","first-page":"105610","DOI":"10.1016\/j.reactfunctpolym.2023.105610","volume":"189","author":"Z Wang","year":"2023","unstructured":"Wang Z, Feng G, Yan Z et al (2023) Improving the hydrophilicity and antifouling performance of PVDF membranes via PEI amination and further poly (methyl vinyl ether-alt-maleic anhydride) modification. Reactive Funct Polym 189:105610. https:\/\/doi.org\/10.1016\/j.reactfunctpolym.2023.105610","journal-title":"Reactive Funct Polym"},{"key":"1120_CR50","doi-asserted-by":"publisher","first-page":"132780","DOI":"10.1016\/j.biortech.2025.132780","volume":"434","author":"Y Zhang","year":"2025","unstructured":"Zhang Y, E J, Chen C et al (2025) Schizochytrium limacinum valorizes volatile fatty acid-rich dark fermentative effluent for docosahexaenoic acid production. Bioresour Technol 434:132780. https:\/\/doi.org\/10.1016\/j.biortech.2025.132780","journal-title":"Bioresour Technol"}],"container-title":["Bioresources and Bioprocessing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40643-026-01120-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40643-026-01120-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40643-026-01120-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T04:07:53Z","timestamp":1788149273000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s40643-026-01120-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":50,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1120"],"URL":"https:\/\/doi.org\/10.1186\/s40643-026-01120-6","relation":{},"ISSN":["2197-4365"],"issn-type":[{"value":"2197-4365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]},"assertion":[{"value":"23 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 August 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 August 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"During the preparation of this work, the authors used ChatGPT (OpenAI), and DeepL Write (DeepL SE), to improve grammar, spelling, clarity, and readability. After using these tools, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication.","order":4,"name":"Ethics","label":"Use of generative AI tools","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"123"}}