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The participants underwent a comprehensive ophthalmic examination including subjective refraction, autorefraction, and IOL-Master. The crystalline lens power was calculated using Bennett\u2019s formula.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>A total of 4177 adults were included. A linear decrease in lens power was observed both with age and with AL, followed by a stop of lens power loss after the age of 70 or when AL \u2265\u00a025\u2009mm, respectively. Participants with Type 2 DM presented higher lens power (0.43 diopter (D), <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001) and thicker lens thickness (0.06\u2009mm, <jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001). In multivariate regression models, there was a positive correlation between lens power and Type 2 DM when age\u2009&lt;\u200975\u2009years (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001) or AL &lt;\u200925\u2009mm (<jats:italic>p<\/jats:italic>\u00a0&lt;\u20090.001) after adjusting for other factors, while no significant association was found in participants aged \u2265\u00a075\u2009years (<jats:italic>p<\/jats:italic>\u00a0=\u20090.122) or with AL \u2265\u00a025\u2009mm (<jats:italic>p<\/jats:italic>\u00a0=\u20090.172).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The lens power in adults aged 50 and above exhibited two stages with age and with AL. Type 2 DM caused an increase in lens power, which was not seen in participants aged \u2265\u00a075\u2009years or with AL \u2265\u00a025\u2009mm.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s40662-020-00222-2","type":"journal-article","created":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T03:02:33Z","timestamp":1606791753000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The associations of lens power with age, axial length and type 2 diabetes mellitus in Chinese adults aged 50 and above"],"prefix":"10.1186","volume":"7","author":[{"given":"Luyao","family":"Ye","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangnan","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinji","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianfeng","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6831-7560","authenticated-orcid":false,"given":"Haidong","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,12,1]]},"reference":[{"issue":"6","key":"222_CR1","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1001\/archopht.1985.01050060045020","volume":"103","author":"RA Gordon","year":"1985","unstructured":"Gordon RA, Donzis PB. 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This study was approved by the Ethics Committee of Shanghai General Hospital, Shanghai Jiao Tong University (Approval number: 2013KY023 for the diabetic eye survey and 2015KY153 for the SESOP study).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"57"}}