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The EDoF-IOL was implanted bilaterally. Three months postoperatively, manifest refraction, monocular and binocular uncorrected and corrected visual acuity at 4\u00a0m, 66\u00a0cm and 40\u00a0cm, binocular defocus curve, binocular contrast sensitivity, halometry and Strehl ratio were measured. Visual disturbances and spectacle independence were assessed with McAlinden and IOLSAT questionnaires, respectively. Assuming a minimum Pearson r correlation coefficient between variables of 0.5 with a power of 80% and a <jats:italic>P<\/jats:italic> value less than 0.05, a minimum sample size of 29 (58 eyes) cases was required.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Forty-three patients were enrolled. Binocular distance corrected visual acuity was lower than 0.1 logMAR for a defocus between\u2009+\u20091.0 and\u2009\u2212\u20091.5 D. The mean values at 66\u00a0cm and 40\u00a0cm were\u2009\u2212\u20090.07\u2009\u00b1\u20090.06 and 0.19\u2009\u00b1\u20090.13 logMAR, respectively. McAlinden\u2019s questionnaire revealed mean scores close to zero for all questions. The IOLSAT questionnaire showed that spectacles were never used for distance and intermediate vision. Regression analysis did not disclose any significant correlation between the preoperatively measured variables and the postoperative outcomes, with a few exceptions: preoperative higher order corneal aberrations were correlated to halometry area (r<jats:sup>2<\/jats:sup>\u2009=\u20090.2592, <jats:italic>P<\/jats:italic>\u2009=\u20090.0006) and the Q value to contrast sensitivity (r<jats:sup>2<\/jats:sup>\u2009=\u20090.1717, <jats:italic>P<\/jats:italic>\u2009=\u20090.00574) under photopic conditions with glare at a spatial frequency of 18\u00a0cpd and without glare for all spatial frequencies (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01); it was also correlated to contrast sensitivity under mesopic conditions without glare at a spatial frequency of 12 cpd (r<jats:sup>2<\/jats:sup>\u2009=\u20090.2311, <jats:italic>P<\/jats:italic>\u2009=\u20090.0011).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>In healthy unoperated eyes, the visual outcomes for this EDoF-IOL are independent of most of the patients\u2019 preoperative parameters. Attention should be paid to preoperative corneal aberrations and asphericity, which did not lead to visual disturbances, but may be potential sources of halo and reduced contrast sensitivity.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s40662-024-00424-y","type":"journal-article","created":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T00:02:57Z","timestamp":1738454577000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Influence of preoperative variables on the 3-month functional outcomes of the Vivity extended depth-of-focus intraocular lens: a prospective case series"],"prefix":"10.1186","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0075-3582","authenticated-orcid":false,"given":"Giacomo","family":"Savini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Galzignato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catarina P.","family":"Coutinho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhai","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piero","family":"Barboni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Mendanha Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filomena J.","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Schiano-Lomoriello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,2]]},"reference":[{"key":"424_CR1","doi-asserted-by":"publisher","first-page":"2449","DOI":"10.2147\/OPTH.S400083","volume":"17","author":"T Kohnen","year":"2023","unstructured":"Kohnen T, Berdhal JP, Hong X, Bala C. 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CC has received personal fees from Zeiss (Germany). For the other authors, no financial interests were declared.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"8"}}