{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T04:24:26Z","timestamp":1772684666905,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T00:00:00Z","timestamp":1576627200000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Implant Dent"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Aim<\/jats:title>\n<jats:p>To evaluate and compare radiographic crestal bone loss (CBL) and soft tissue parameters around submerged\/two-stage and nonsubmerged\/one-stage single implants with the same endosseous portion (body design and surface, thread design and distance) and identical intramucosal laser-microgrooved surface, after 3\u2009years of loading.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Materials and methods<\/jats:title>\n<jats:p>Twenty submerged\/two-stage implants and 20 nonsubmerged\/one-stage implants were placed randomly with a split-mouth design in the posterior areas of 20 partially edentulous patients.<\/jats:p>\n<jats:p>Radiographic and clinical examinations were carried out at the implant placement, at the delivery of prosthetic restorations, and at each year of the follow-up period. Plaque index (PI), probing depth (PD), bleeding on probing (BOP), and gingival recession (REC) were recorded. Radiographic crestal bone levels were assessed at the mesial and distal aspect of the implant sites. In addition, the influence of the vertical keratinized tissue thickness (KTT) on CBL was investigated.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>At the delivery of prosthetic restorations, a statistically significant difference (<jats:italic>P<\/jats:italic> = 0.013) was found in radiographic mean CBL between submerged and nonsubmerged implants (0.15 \u00b1 0.05\u2009mm vs. 0.11 \u00b1 0.04\u2009mm). At the end of the follow-up period, no statistical difference (<jats:italic>P<\/jats:italic> = 0.741) was found in the mean CBL between submerged and nonsubmerged implants (0.27 \u00b1 04\u2009mm vs. 0.26 \u00b1 0.5\u2009mm). The changes in the soft tissues including PI, PD, BOP, and REC had no significant differences in either group. Moreover, KTT did not show a statistical correlation with CBL.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>After 3\u2009years of loading, no statistical difference was noted in CBL and soft tissue conditions between single submerged two-stage and nonsubmerged one-stage laser-microgrooved implants.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Trial registration<\/jats:title>\n<jats:p><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/clinicaltrials.gov\/ct2\/show\/NCT03674762\">http:\/\/clinicaltrials.gov\/ct2\/show\/NCT03674762<\/jats:ext-link><\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s40729-019-0196-0","type":"journal-article","created":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T00:06:35Z","timestamp":1576627595000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical and radiographics results at 3 years of RCT with split-mouth design of submerged vs. nonsubmerged single laser-microgrooved implants in posterior areas"],"prefix":"10.1186","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1449-8340","authenticated-orcid":false,"given":"Renzo","family":"Guarnieri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Di Nardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianni","family":"Di Giorgio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Miccoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Testarelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,12,18]]},"reference":[{"key":"196_CR1","first-page":"CD003815","volume":"1","author":"M Esposito","year":"2005","unstructured":"Esposito M, Coulthard P, Thomsen P, Worthington HV. 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All patients were informed that two different implants were used and gave their informed consent to the treatment","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Renzo Guarnieri, Dario Di Nardo, Gianni Di Giorgio, Gabriele Miccoli, and Luca Testarelli state that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"44"}}