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Dimensional changes were assessed by CBCT at baseline, 3\u00a0months, and 6\u00a0months. Histomorphometric analysis was performed on bone core biopsies harvested at 6\u00a0months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty patients were enrolled and randomly assigned to the test (DDM, n\u2009=\u200925) or control (DBBM, n\u2009=\u200925) group. At 3\u00a0months post-surgery, the test group exhibited significantly greater horizontal bone resorption at the mid-socket level (50%) compared with the control group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006). However, at 6\u00a0months, no statistically significant differences were observed between the two groups regarding horizontal width reduction at any level (coronal, middle, apical) or vertical height reduction (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Histomorphometric analysis at 6\u00a0months revealed active new bone formation and good integration of graft particles in the DDM group, confirming its biodegradability and osteoconductive potential.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although autogenous DDM exhibited a faster remodeling rate and dimensional contraction in the early healing phase (3\u00a0months), it achieved long-term (6-month) dimensional stability comparable with that of the gold-standard xenograft. Furthermore, histological evidence of superior tissue integration suggests that DDM is a biologically viable and cost-effective alternative for alveolar ridge preservation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s40729-026-00682-6","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T16:35:47Z","timestamp":1779467747000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical, radiographic, and histological evaluation of autogenous demineralized dentin matrix versus xenograft in alveolar ridge preservation: a randomized controlled trial"],"prefix":"10.1186","volume":"12","author":[{"given":"Yin","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"682_CR1","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/odi.14516","volume":"30","author":"N Jain","year":"2023","unstructured":"Jain N, Dutt U, Radenkov I, Jain S. 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