{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T13:23:34Z","timestamp":1780493014557,"version":"3.54.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T00:00:00Z","timestamp":1568332800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T00:00:00Z","timestamp":1568332800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["surg case rep"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n              <jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Solitary fibrous tumor (SFT) is a rare mesenchymal tumor that typically arises from the pleura. Although it may appear in other organs, it rarely develops in the pancreas. We report herein a rare case of metastatic SFT of the pancreas originating from an intracranial tumor and subsequently identified as a cystic neoplasm of the pancreas.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 58-year-old woman with a past medical history of brain tumor visited the hospital for further investigation of a cystic tumor in the pancreas tail. Abdominal imaging showed a heterogeneously enhancing mass that was initially suspected as a neuroendocrine neoplasm, solid pseudopapillary neoplasm, or mucinous cystic neoplasm of the pancreas. Distal pancreatectomy was performed without any intraoperative and postoperative complications. Pathological findings confirmed a diagnosis of malignant SFT of the pancreas with hyperproliferative potential. A histopathological review of her brain tumor revealed that the pancreatic tumor was derived from her brain lesion. The patient developed recurrent brain disease 4\u2009years after the pancreatectomy, but no recurrence has been observed in the abdominal cavity.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>SFT should be considered in the differential diagnosis of untypical hypervascular pancreatic mass, particularly in patients with a history of an intrathoracic or intracranial mesenchymal tumor. Immunohistochemical analysis is crucial in detecting this tumor entity. Hyperproliferative status indicates a malignant disease and requires careful postoperative observation.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40792-019-0699-1","type":"journal-article","created":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T04:39:46Z","timestamp":1568349586000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report"],"prefix":"10.1186","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3141-8536","authenticated-orcid":false,"given":"Hironori","family":"Yamashita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Fujino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadayuki","family":"Ohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keitaro","family":"Kakinoki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takemi","family":"Sugimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyoshi","family":"Kajimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Tominaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,9,13]]},"reference":[{"issue":"1","key":"699_CR1","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s004280050392","volume":"435","author":"J Luttges","year":"1999","unstructured":"Luttges J, et al. Solitary fibrous tumour of the pancreas: a new member of the small group of mesenchymal pancreatic tumours. Virchows Arch. 1999;435(1):37\u201342.","journal-title":"Virchows Arch"},{"issue":"3","key":"699_CR2","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1177\/1066896907302419","volume":"15","author":"H Miyamoto","year":"2007","unstructured":"Miyamoto H, et al. Solitary fibrous tumor of the pancreas: a case report. Int J Surg Pathol. 2007;15(3):311\u20134.","journal-title":"Int J Surg Pathol"},{"issue":"4","key":"699_CR3","first-page":"526","volume":"9","author":"VD Srinivasan","year":"2008","unstructured":"Srinivasan VD, et al. Solitary fibrous tumor of the pancreas: case report with cytologic and surgical pathology correlation and review of the literature. JOP. 2008;9(4):526\u201330.","journal-title":"JOP"},{"issue":"Suppl","key":"699_CR4","doi-asserted-by":"publisher","first-page":"S48","DOI":"10.3348\/kjr.2008.9.s.s48","volume":"9","author":"HJ Kwon","year":"2008","unstructured":"Kwon HJ, et al. Solitary fibrous tumor of the pancreas: imaging findings. Korean J Radiol. 2008;9(Suppl):S48\u201351.","journal-title":"Korean J Radiol"},{"issue":"5","key":"699_CR5","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.anndiagpath.2009.02.006","volume":"13","author":"R Chetty","year":"2009","unstructured":"Chetty R, Jain R, Serra S. Solitary fibrous tumor of the pancreas. Ann Diagn Pathol. 2009;13(5):339\u201343.","journal-title":"Ann Diagn Pathol"},{"issue":"6","key":"699_CR6","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s11604-010-0453-x","volume":"28","author":"Y Sugawara","year":"2010","unstructured":"Sugawara Y, et al. Solitary fibrous tumor of the pancreas. Jpn J Radiol. 2010;28(6):479\u201382.","journal-title":"Jpn J Radiol"},{"issue":"1","key":"699_CR7","doi-asserted-by":"publisher","first-page":"133","DOI":"10.4321\/S1137-66272012000100013","volume":"35","author":"LA Santos","year":"2012","unstructured":"Santos LA, et al. Solitary fibrous tumour of the pancreas: a case report. An Sist Sanit Navar. 2012;35(1):133\u20136.","journal-title":"An Sist Sanit Navar"},{"issue":"3","key":"699_CR8","first-page":"304","volume":"13","author":"A Tasdemir","year":"2012","unstructured":"Tasdemir A, et al. A huge solitary fibrous tumor localized in the pancreas: a young women. JOP. 2012;13(3):304\u20137.","journal-title":"JOP"},{"issue":"3","key":"699_CR9","first-page":"32","volume":"6","author":"J Azadi","year":"2012","unstructured":"Azadi J, Subhawong A, Durand DJ. F-18 FDG PET\/CT and Tc-99m sulfur colloid SPECT imaging in the diagnosis and treatment of a case of dual solitary fibrous tumors of the retroperitoneum and pancreas. J Radiol Case Rep. 2012;6(3):32\u20137.","journal-title":"J Radiol Case Rep"},{"issue":"7","key":"699_CR10","doi-asserted-by":"publisher","first-page":"180","DOI":"10.4240\/wjgs.v4.i7.180","volume":"4","author":"JR van der Vorst","year":"2012","unstructured":"van der Vorst JR, et al. Near-infrared fluorescence imaging of a solitary fibrous tumor of the pancreas using methylene blue. World J Gastrointest Surg. 2012;4(7):180\u20134.","journal-title":"World J Gastrointest Surg"},{"issue":"6","key":"699_CR11","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.pan.2013.06.004","volume":"13","author":"YA Patel","year":"2013","unstructured":"Patel YA, et al. Pancreatic metastasis from a solitary fibrous tumor of the kidney: a rare cause of acute recurrent pancreatitis. Pancreatology. 2013;13(6):631\u20133.","journal-title":"Pancreatology"},{"issue":"1","key":"699_CR12","first-page":"58","volume":"15","author":"T Osuga","year":"2014","unstructured":"Osuga T, et al. Pancreatic metastasis from a solitary fibrous tumor of the central nervous system. JOP. 2014;15(1):58\u201362.","journal-title":"JOP"},{"issue":"6","key":"699_CR13","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1097\/MPA.0000000000000350","volume":"44","author":"JS Estrella","year":"2015","unstructured":"Estrella JS, et al. Malignant solitary fibrous tumor of the pancreas. Pancreas. 2015;44(6):988\u201394.","journal-title":"Pancreas"},{"issue":"12","key":"699_CR14","doi-asserted-by":"publisher","first-page":"rjv144","DOI":"10.1093\/jscr\/rjv144","volume":"2015","author":"Andrew R. Baxter","year":"2015","unstructured":"Baxter AR, Newman E, Hajdu CH. Solitary fibrous tumor of the pancreas. J Surg Case Rep. 2015;2015(12):rjv144.","journal-title":"Journal of Surgical Case Reports"},{"issue":"6","key":"699_CR15","doi-asserted-by":"publisher","first-page":"461","DOI":"10.4240\/wjgs.v8.i6.461","volume":"8","author":"D Paramythiotis","year":"2016","unstructured":"Paramythiotis D, et al. Solitary fibrous tumor of the pancreas: case report and review of the literature. World J Gastrointest Surg. 2016;8(6):461\u20136.","journal-title":"World J Gastrointest Surg"},{"key":"699_CR16","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.mce.2016.08.044","volume":"436","author":"K Murakami","year":"2016","unstructured":"Murakami K, et al. Pancreatic solitary fibrous tumor causing ectopic adrenocorticotropic hormone syndrome. Mol Cell Endocrinol. 2016;436:268\u201373.","journal-title":"Mol Cell Endocrinol"},{"issue":"2\u20133","key":"699_CR17","first-page":"115","volume":"37","author":"L Spasevska","year":"2016","unstructured":"Spasevska L, et al. Solitary fibrous tumor of the pancreas: a case report and review of the literature. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2016;37(2\u20133):115\u201320.","journal-title":"Pril (Makedon Akad Nauk Umet Odd Med Nauki)"},{"key":"699_CR18","doi-asserted-by":"publisher","first-page":"1853","DOI":"10.2147\/OTT.S133650","volume":"10","author":"Q Sheng","year":"2017","unstructured":"Sheng Q, et al. Pancreatic solitary fibrous tumor in a toddler managed by pancreaticoduodenectomy: a case report and review of the literature. Onco Targets Ther. 2017;10:1853\u20138.","journal-title":"Onco Targets Ther"},{"key":"699_CR19","doi-asserted-by":"crossref","unstructured":"Colvin JS, et al. Pancreatic metastasis from an osseous solitary fibrous tumour. BMJ Case Rep. 2017;2017:bcr-2017-220114.","DOI":"10.1136\/bcr-2017-220114"},{"issue":"6","key":"699_CR20","first-page":"3093","volume":"37","author":"FE D\u2019Amico","year":"2017","unstructured":"D\u2019Amico FE, et al. Rare neoplasm mimicking neuoroendocrine pancreatic tumor: a case report of solitary fibrous tumor with review of the literature. Anticancer Res. 2017;37(6):3093\u20137.","journal-title":"Anticancer Res"},{"issue":"6","key":"699_CR21","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1007\/s12328-017-0774-8","volume":"10","author":"S Oana","year":"2017","unstructured":"Oana S, et al. A case of a \u201cwandering\u201d mobile solitary fibrous tumor occurring in the pancreas. Clin J Gastroenterol. 2017;10(6):535\u201340.","journal-title":"Clin J Gastroenterol"},{"issue":"3","key":"699_CR22","first-page":"387","volume":"11","author":"P Klemperer","year":"1931","unstructured":"Klemperer P, Rabin CB. Primary neoplasms of the pleura - a report of five cases. Arch Pathol. 1931;11(3):387\u2013414.","journal-title":"Arch Pathol"},{"issue":"4","key":"699_CR23","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1177\/1066896911405655","volume":"19","author":"M Bisceglia","year":"2011","unstructured":"Bisceglia M, et al. Solitary fibrous tumor of the central nervous system: report of an additional 5 cases with comprehensive literature review. Int J Surg Pathol. 2011;19(4):476\u201386.","journal-title":"Int J Surg Pathol"},{"issue":"2","key":"699_CR24","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3109\/01676830.2013.853806","volume":"33","author":"CP Le","year":"2014","unstructured":"Le CP, Jones S, Valenzuela AA. Orbital solitary fibrous tumor: a case series with review of the literature. Orbit. 2014;33(2):145\u201351.","journal-title":"Orbit"},{"issue":"4","key":"699_CR25","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1007\/s12105-017-0878-y","volume":"12","author":"Lester D. R. Thompson","year":"2017","unstructured":"Thompson LDR, Lau SK. Sinonasal tract solitary fibrous tumor: a clinicopathologic study of six cases with a comprehensive review of the literature. Head Neck Pathol. 2018;12(4):471\u201380.","journal-title":"Head and Neck Pathology"},{"key":"699_CR26","doi-asserted-by":"publisher","first-page":"206","DOI":"10.7150\/jca.2.206","volume":"2","author":"Z Song","year":"2011","unstructured":"Song Z, et al. Primary solitary fibrous tumor of the thyroid - report of a case and review of the literature. J Cancer. 2011;2:206\u20139.","journal-title":"J Cancer"},{"issue":"2","key":"699_CR27","doi-asserted-by":"publisher","first-page":"156","DOI":"10.14701\/ahbps.2018.22.2.156","volume":"22","author":"RS Shinde","year":"2018","unstructured":"Shinde RS, et al. Solitary fibrous tumor of the liver - an unusual entity: a case report and review of literature. Ann Hepatobiliary Pancreat Surg. 2018;22(2):156\u20138.","journal-title":"Ann Hepatobiliary Pancreat Surg"},{"issue":"1","key":"699_CR28","first-page":"36","volume":"9","author":"K Znati","year":"2007","unstructured":"Znati K, et al. Solitary fibrous tumor of the kidney: a case report and review of the literature. Rev Urol. 2007;9(1):36\u201340.","journal-title":"Rev Urol"},{"issue":"1","key":"699_CR29","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/his.12267","volume":"64","author":"CD Fletcher","year":"2014","unstructured":"Fletcher CD. The evolving classification of soft tissue tumours - an update based on the new 2013 WHO classification. Histopathology. 2014;64(1):2\u201311.","journal-title":"Histopathology"},{"issue":"3","key":"699_CR30","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1038\/modpathol.2013.164","volume":"27","author":"LA Doyle","year":"2014","unstructured":"Doyle LA, et al. Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. Mod Pathol. 2014;27(3):390\u20135.","journal-title":"Mod Pathol"},{"issue":"4","key":"699_CR31","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1097\/PAS.0000000000000137","volume":"38","author":"A Yoshida","year":"2014","unstructured":"Yoshida A, et al. STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors. Am J Surg Pathol. 2014;38(4):552\u20139.","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"699_CR32","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1046\/j.1365-2559.1998.00412.x","volume":"32","author":"T Yokoi","year":"1998","unstructured":"Yokoi T, et al. Solitary fibrous tumour: significance of p53 and CD34 immunoreactivity in its malignant transformation. Histopathology. 1998;32(5):423\u201332.","journal-title":"Histopathology"},{"issue":"4","key":"699_CR33","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1002\/cncr.10328","volume":"94","author":"JS Gold","year":"2002","unstructured":"Gold JS, et al. Clinicopathologic correlates of solitary fibrous tumors. Cancer. 2002;94(4):1057\u201368.","journal-title":"Cancer"},{"issue":"2","key":"699_CR34","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1093\/ajcp\/106.2.217","volume":"106","author":"SS Carneiro","year":"1996","unstructured":"Carneiro SS, et al. Solitary fibrous tumor of the meninges: a lesion distinct from fibrous meningioma. A clinicopathologic and immunohistochemical study. Am J Clin Pathol. 1996;106(2):217\u201324.","journal-title":"Am J Clin Pathol"},{"issue":"6","key":"699_CR35","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s00401-016-1545-1","volume":"131","author":"DN Louis","year":"2016","unstructured":"Louis DN, et al. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol. 2016;131(6):803\u201320.","journal-title":"Acta Neuropathol"},{"issue":"13","key":"699_CR36","doi-asserted-by":"publisher","first-page":"3865","DOI":"10.1245\/s10434-017-6092-z","volume":"24","author":"S Gholami","year":"2017","unstructured":"Gholami S, et al. Size and location are the most important risk factors for malignant behavior in resected solitary fibrous tumors. Ann Surg Oncol. 2017;24(13):3865\u201371.","journal-title":"Ann Surg Oncol"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-019-0699-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s40792-019-0699-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-019-0699-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T23:05:34Z","timestamp":1599865534000},"score":1,"resource":{"primary":{"URL":"https:\/\/surgicalcasereports.springeropen.com\/articles\/10.1186\/s40792-019-0699-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,13]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["699"],"URL":"https:\/\/doi.org\/10.1186\/s40792-019-0699-1","relation":{},"ISSN":["2198-7793"],"issn-type":[{"value":"2198-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,13]]},"assertion":[{"value":"26 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 August 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This case report has been approved by the Research Ethics Committee of Hyogo Cancer Center.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent for publication of this case report was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"142"}}