{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T10:31:23Z","timestamp":1750156283540,"version":"3.37.3"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,12,12]],"date-time":"2019-12-12T00:00:00Z","timestamp":1576108800000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["surg case rep"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>Although complete surgical resection of thymic carcinoma is a prognostic factor, it is not always an option for advanced tumors because of locoregional invasion. Extended surgery combined with a major blood vessel procedure remains controversial because of the increased risk of mortality.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Case presentation<\/jats:title>\n<jats:p>Chest computed tomography (CT) uncovered an abnormal shadow in the mediastinum of a 74-year-old man. An irregularly shaped tumor obstructed the left innominate vein, and invasion of the aortic arch was suspected. A CT-guided percutaneous needle biopsy revealed squamous cell carcinoma of the thymus, which was considered unresectable. The patient underwent chemotherapy elsewhere, then was referred to us for surgical resection. We combined extended surgery with total aortic arch replacement under a cardiopulmonary bypass. Complete resection was achieved, and the patient remains alive without recurrence at 3\u2009years after surgery<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Resection including aortic arch replacement might be an option that can achieve complete resection of local advanced thymic carcinoma.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s40792-019-0713-7","type":"journal-article","created":{"date-parts":[[2019,12,12]],"date-time":"2019-12-12T17:05:02Z","timestamp":1576170302000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Complete resection of local advanced thymic carcinoma with total aortic arch replacement after chemotherapy: a case report"],"prefix":"10.1186","volume":"5","author":[{"given":"Hidenori","family":"Kuno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soichiro","family":"Funaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Shimamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiwa","family":"Kin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Kuratani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Sawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2540-5288","authenticated-orcid":false,"given":"Yasushi","family":"Shintani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,12,12]]},"reference":[{"key":"713_CR1","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1097\/JTO.0000000000000128","volume":"9","author":"E Ruffini","year":"2014","unstructured":"Ruffini E, Detterbeck F, Van Raemdonck D, Rocco G, Thomas P, Weder W, et al. Thymic carcinoma: a cohort study of patients from the European society of Thoracic Surgeons database. J Thorac Oncol. 2014;9:541\u20138.","journal-title":"J Thorac Oncol"},{"key":"713_CR2","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.jtcvs.2014.09.124","volume":"149","author":"O Ahmad","year":"2015","unstructured":"Ahmad O, Yao X, Detterbeck F, Huang J, Antonecelli A, Filosso PL, et al. Thymic carcinoma outcomes and prognosis: results of an international analysis. J Thorac Cardiovasc Surg. 2015;149:95\u2013100.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"713_CR3","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1016\/j.athoracsur.2012.09.006","volume":"95","author":"B Weksler","year":"2013","unstructured":"Weksler B, Dhupar R, Parikh V, Nason KS, Pennathur A, Ferson PF. Thymic carcinoma: a multivariate analysis of factors predictive of survival in 290 patients. Ann Thorac Surg. 2013;95:299\u2013303.","journal-title":"Ann Thorac Surg"},{"issue":"3","key":"713_CR4","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1093\/ejcts\/ezv239","volume":"49","author":"T Hishida","year":"2016","unstructured":"Hishida T, Nomura S, Yano M, Asamura H, Yamashita M, Ohde Y, et al. Long-term outcome and prognostic factors of surgically treated thymic carcinoma: results of 306 cases from Japanese Nationwide Database Study. Eur J Cardiothorac Surg. 2016;49(3):835\u201341.","journal-title":"Eur J Cardiothorac Surg"},{"issue":"3","key":"713_CR5","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s11748-014-0486-7","volume":"63","author":"Y Shintani","year":"2015","unstructured":"Shintani Y, Inoue M, Kawamura T, Funaki S, Minami M, Okumura M. Multimodality treatment for advanced thymic carcinoma: outcomes of induction therapy followed by surgical resection in 16 cases at a single institution. Gen Thorac Cardiovasc Surg. 2015;63(3):159\u201363.","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"713_CR6","unstructured":"National Comprehensive Cancer network. NCCN clinical practice guidelines in oncology (NCCN guidelines) Thymoma and Thymic carcinoma, version 2. 2018. Available online: https:\/\/www.nccn.org\/professionals\/physician_gls\/default.aspx."},{"issue":"2","key":"713_CR7","doi-asserted-by":"publisher","first-page":"e139","DOI":"10.1016\/j.athoracsur.2016.01.014","volume":"102","author":"T Momozane","year":"2016","unstructured":"Momozane T, Inoue M, Shintani Y, Funaki S, Kawamura T, Minami M, et al. Trimodality therapy for an advanced thymic carcinoma with both aorta and vena cava invasion. Ann Thorac Surg. 2016;102(2):e139\u201341.","journal-title":"Ann Thorac Surg"},{"issue":"7","key":"713_CR8","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1007\/BF03032300","volume":"50","author":"T Takahashi","year":"2002","unstructured":"Takahashi T, Suzuki K, Ito Y, Takinami M, Yamashita K, Kazui T. Aortic arch resection under temporary bypass grafting for advanced thymic cancer. Jpn J Thorac Cardiovasc Surg. 2002;50(7):302\u20134.","journal-title":"Jpn J Thorac Cardiovasc Surg"},{"issue":"6","key":"713_CR9","doi-asserted-by":"publisher","first-page":"e557","DOI":"10.1016\/j.athoracsur.2016.05.095","volume":"102","author":"S Oka","year":"2016","unstructured":"Oka S, Taira A, Shinohara S, Kuwata T, Takenaka M, Chikaishi Y, et al. Complete Resection of Thymic Sarcomatoid Carcinoma Through Total Aortic Arch Replacement. Ann Thorac Surg. 2016;102(6):e557\u2013e59.","journal-title":"Ann Thorac Surg"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-019-0713-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s40792-019-0713-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-019-0713-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T00:30:35Z","timestamp":1607646635000},"score":1,"resource":{"primary":{"URL":"https:\/\/surgicalcasereports.springeropen.com\/articles\/10.1186\/s40792-019-0713-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["713"],"URL":"https:\/\/doi.org\/10.1186\/s40792-019-0713-7","relation":{},"ISSN":["2198-7793"],"issn-type":[{"type":"electronic","value":"2198-7793"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"25 July 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 September 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 December 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The patient provided written, informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"198"}}