{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:53:58Z","timestamp":1740174838728,"version":"3.37.3"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T00:00:00Z","timestamp":1611360000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T00:00:00Z","timestamp":1611360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["surg case rep"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Cyclic neutropenia is a disease that causes a neutropenic decrease in peripheral blood in a cycle of about 21\u00a0days. It is a rare hereditary disorder with an estimated incidence of 0.5\u20131 cases per million population. The absolute neutrophil count can drop to zero, and neutropenic nadir may last for 3\u20135 days. This is a rare disease, and there are few reports of abdominal surgery in cyclic neutropenia patients; thus, we report this case of neutrophil count fluctuation and perioperative management.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 31-year-old man with cyclic neutropenia was transferred to our hospital complaining of right season rib pain, but no rebound tenderness. His C-reactive protein was elevated (4.37\u00a0mg\/L) and computed tomography revealed a large number of small stones in the gallbladder body and an incarceration in the gallbladder neck. He was diagnosed with acute cholecystitis. Ideally, surgical intervention should have been performed immediately, but because his neutrophil count was 300\/\u03bcL, endoscopic naso-gallbladder drainage was performed and he was provided antibiotics until his neutrophil count increased to acceptable levels. Three days after admission, his neutrophil count had increased and laparoscopic cholecystectomy was performed. For one week after the operation, antibiotics were administered; he had an uneventful postoperative recovery. He was discharged on the seventh postoperative day and provided an oral antibiotic.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Infection can be serious in patients with cyclic neutropenia, and it is therefore, important to determine the timing of surgery and to apply appropriate perioperative management with drainage and antibiotic administration.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40792-021-01117-7","type":"journal-article","created":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T08:02:59Z","timestamp":1611388979000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of acute cholecystitis in patient with cyclic neutropenia: a case report"],"prefix":"10.1186","volume":"7","author":[{"given":"Saki","family":"Nishikawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8546-9876","authenticated-orcid":false,"given":"Michinori","family":"Hamaoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Nakahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiyuki","family":"Itamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,1,23]]},"reference":[{"key":"1117_CR1","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.2147\/TCRM.S89488","volume":"11","author":"N Glavan","year":"2015","unstructured":"Glavan N, Roganovi\u0107 J, Glavan-Ga\u010danin L, Jonji\u0107 N. Appendectomy in a child with cyclic neutropenia in profound neutropenic episode. Ther Clin Risk Manag. 2015;11:1217\u20139.","journal-title":"Ther Clin Risk Manag"},{"key":"1117_CR2","volume-title":"Cyclic neutropenia. StatPearls","author":"AS Zergham","year":"2020","unstructured":"Zergham AS, Acharya U. Cyclic neutropenia. StatPearls. Treasure Island: StatPearls Publishing LLC; 2020."},{"issue":"4","key":"1117_CR3","first-page":"363","volume":"3","author":"RD Lange","year":"1981","unstructured":"Lange RD, Jones JB. Cyclic neutropenia. Review of clinical manifestations and management. Am J Pediatr Hematol Oncol. 1981;3(4):363\u20137.","journal-title":"Am J Pediatr Hematol Oncol."},{"issue":"2","key":"1117_CR4","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1002\/ajh.10255","volume":"72","author":"DC Dale","year":"2003","unstructured":"Dale DC, Cottle TE, Fier CJ, Bolyard AA, Bonilla MA, Boxer LA, et al. Severe chronic neutropenia: treatment and follow-up of patients in the Severe Chronic Neutropenia International Registry. Am J Hematol. 2003;72(2):82\u201393.","journal-title":"Am J Hematol"},{"issue":"3","key":"1117_CR5","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/0022-3468(73)90105-X","volume":"8","author":"GW Geelhoed","year":"1973","unstructured":"Geelhoed GW, Kane MA, Dale DC, Wells SA. Colon ulceration and perforation in cyclic neutropenia. J Pediatr Surg. 1973;8(3):379\u201382.","journal-title":"J Pediatr Surg"},{"issue":"12","key":"1117_CR6","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1007\/BF02050076","volume":"34","author":"T O'Hanrahan","year":"1991","unstructured":"O\u2019Hanrahan T, Dark P, Irving MH. Cyclic neutropenia\u2013unusual cause of acute abdomen. Report of a case. Dis Colon Rectum. 1991;34(12):1125\u20137.","journal-title":"Dis Colon Rectum."},{"issue":"3","key":"1117_CR7","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1016\/0022-3468(90)90084-M","volume":"25","author":"JC Langer","year":"1990","unstructured":"Langer JC, Papa MZ, Hoffman MA, Loeff DS, Pearl RH, Filler RM. Cyclic neutropenia with colonic perforation and nonhealing colocutaneous fistula. J Pediatr Surg. 1990;25(3):346\u20138.","journal-title":"J Pediatr Surg"},{"issue":"5","key":"1117_CR8","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1182\/blood-2006-08-019166","volume":"109","author":"MS Horwitz","year":"2007","unstructured":"Horwitz MS, Duan Z, Korkmaz B, Lee HH, Mealiffe ME, Salipante SJ. Neutrophil elastase in cyclic and severe congenital neutropenia. Blood. 2007;109(5):1817\u201324.","journal-title":"Blood"},{"issue":"1","key":"1117_CR9","doi-asserted-by":"publisher","first-page":"193","DOI":"10.2214\/ajr.183.1.1830193","volume":"183","author":"K Ito","year":"2004","unstructured":"Ito K, Fujita N, Noda Y, Kobayashi G, Kimura K, Sugawara T, et al. Percutaneous cholecystostomy versus gallbladder aspiration for acute cholecystitis: a prospective randomized controlled trial. AJR Am J Roentgenol. 2004;183(1):193\u20136.","journal-title":"AJR Am J Roentgenol"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-021-01117-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s40792-021-01117-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-021-01117-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,23]],"date-time":"2021-01-23T08:46:23Z","timestamp":1611391583000},"score":1,"resource":{"primary":{"URL":"https:\/\/surgicalcasereports.springeropen.com\/articles\/10.1186\/s40792-021-01117-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,23]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["1117"],"URL":"https:\/\/doi.org\/10.1186\/s40792-021-01117-7","relation":{},"ISSN":["2198-7793"],"issn-type":[{"type":"electronic","value":"2198-7793"}],"subject":[],"published":{"date-parts":[[2021,1,23]]},"assertion":[{"value":"26 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 January 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study conforms to the provisions of the Declaration of Helsinki. The subject gave informed consent, and patient anonymity was preserved.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"We obtained consent from the patient to publish this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"29"}}