{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T05:41:50Z","timestamp":1769578910157,"version":"3.49.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["surg case rep"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Cavitary lesions pathologically diagnosed as adenocarcinoma in situ (AIS) have been rarely reported. The examination of these type of lesions is necessary for a better understanding of the mechanisms underlying their formation and development of more efficient diagnostic and treatment strategies. Here, we present the case of a patient with cavitary lung carcinoma, diagnosed as AIS, who underwent partial resection.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>A 72-year-old man presented with an abnormal shadow on chest radiography. Computed tomography findings showed a nodule in the right upper lobe, which was later diagnosed as an adenocarcinoma via transbronchial biopsy. A thin-walled cavity with partial thickening in the right lower lobe was also noted. We suspected that the thin-walled cavitary lesion was malignant, and performed wedge resection during a right upper lobectomy. AIS was diagnosed based on the histopathological findings of the thickened part of the thin-walled cavity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This study highlights that, although rare, AIS may be observed in cavitary lung carcinoma cases, particularly in thin-walled lesions.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40792-022-01413-w","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T12:04:08Z","timestamp":1649073848000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Adenocarcinoma in situ detected on a thin-walled lung cavity: a case report"],"prefix":"10.1186","volume":"8","author":[{"given":"Takashi","family":"Sakai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Azuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Koezuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime","family":"Otsuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Sano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naobumi","family":"Tochigi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0908-4840","authenticated-orcid":false,"given":"Akira","family":"Iyoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,4,4]]},"reference":[{"key":"1413_CR1","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1136\/thx.28.3.354","volume":"28","author":"MR Chaudhuri","year":"1973","unstructured":"Chaudhuri MR. Primary pulmonary cavitating carcinomas. Thorax. 1973;28:354\u201366.","journal-title":"Thorax"},{"key":"1413_CR2","doi-asserted-by":"publisher","first-page":"473","DOI":"10.2214\/ajr.140.3.473","volume":"140","author":"JH Woodring","year":"1983","unstructured":"Woodring JH, Fried AM. Significance of wall thickness in solitary cavities of the lung: a follow-up study. Am J Roentgenol. 1983;140:473\u20134.","journal-title":"Am J Roentgenol"},{"key":"1413_CR3","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1148\/radiol.2371041650","volume":"237","author":"A Onn","year":"2005","unstructured":"Onn A, Choe DH, Herbst RS, Correa AM, Munden RF, Truong MT, et al. Tumor cavitation in stage I non-small cell lung cancer: epidermal growth factor receptor expression and prediction of poor outcome. Radiology. 2005;237:342\u20137.","journal-title":"Radiology"},{"key":"1413_CR4","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/j.athoracsur.2014.10.040","volume":"99","author":"Y Watanabe","year":"2015","unstructured":"Watanabe Y, Kusumoto M, Yoshida A, Suzuki K, Asamura H, Tsuta K. Surgically resected solitary cavitary lung adenocarcinoma: association between clinical, pathologic, and radiologic findings and prognosis. Ann Thorac Surg. 2015;99:968\u201374.","journal-title":"Ann Thorac Surg"},{"key":"1413_CR5","doi-asserted-by":"publisher","first-page":"3148","DOI":"10.21037\/jtd-20-426","volume":"12","author":"Z Liu","year":"2020","unstructured":"Liu Z, Feng H, Zhang Z, Sun H, Liu D. Clinicopathological characteristics of solitary cavitary lung cancer: a case-control study. J Thorac Dis. 2020;12:3148\u201356.","journal-title":"J Thorac Dis"},{"key":"1413_CR6","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.lungcan.2017.08.004","volume":"112","author":"K Tomizawa","year":"2017","unstructured":"Tomizawa K, Shimizu S, Ohara S, Fujino T, Nishino M, Sesumi Y, et al. Clinical significance of tumor cavitation in surgically resected early-stage primary lung cancer. Lung Cancer. 2017;112:57\u201361.","journal-title":"Lung Cancer"},{"key":"1413_CR7","first-page":"109","volume":"11","author":"S Hirai","year":"2005","unstructured":"Hirai S, Hamanaka Y, Mitsui N, Morifuji K, Sutoh M. Primary lung cancer arising from the wall of a giant bulla. Ann Thorac Cardiovasc Surg. 2005;11:109\u201313.","journal-title":"Ann Thorac Cardiovasc Surg"},{"key":"1413_CR8","doi-asserted-by":"publisher","first-page":"249","DOI":"10.2214\/ajr.134.2.249","volume":"134","author":"DJ Aronberg","year":"1980","unstructured":"Aronberg DJ, Sagel SS, LeFrak S, Kuhn C, Susman N. Lung carcinoma associated with bullous lung disease in young men. Am J Roentgenol. 1980;134:249\u201352.","journal-title":"Am J Roentgenol"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-022-01413-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40792-022-01413-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-022-01413-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T12:24:42Z","timestamp":1649075082000},"score":1,"resource":{"primary":{"URL":"https:\/\/surgicalcasereports.springeropen.com\/articles\/10.1186\/s40792-022-01413-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,4]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["1413"],"URL":"https:\/\/doi.org\/10.1186\/s40792-022-01413-w","relation":{},"ISSN":["2198-7793"],"issn-type":[{"value":"2198-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,4]]},"assertion":[{"value":"21 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 April 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013).The study protocol was approved by the Ethics Committee of Faculty of Medicine, Toho University (No. A19039_27128_25095_25047). The patient was provided a concent to participate in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"A written informed consent was obtained from the patient for publication of this report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"60"}}