{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T03:33:58Z","timestamp":1772076838601,"version":"3.50.1"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T00:00:00Z","timestamp":1651708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T00:00:00Z","timestamp":1651708800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["surg case rep"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Pulmonary benign metastasizing leiomyoma (PBML) is a rare disease that can occur in women with a history of uterine leiomyoma. Despite its benign histological features, like a malignancy, leiomyomas can on rare occasion spread to the lung. Typically, PBML presents with asymptomatic multiple solid lung nodules with slow tumor progression, following hysterectomy. Here, we present an atypical case with rapid enlargement of PBML with fluid-containing cystic change.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We experienced a case of a 49-year-old woman with bilateral lung nodules following hysterectomy. Two nodules in the right lung had cystic change with fluid in the tumors. Hormone therapy was initiated after surgical biopsy of the left lung confirmed a diagnosis of PBML. However, the cystic component of right upper lobe lesion enlarged rapidly over the following 7\u00a0months, and, considering the risk of malignant transformation or tumor rupture, right upper lobectomy was performed. Pathologically, the fluid-containing tumor was diagnosed as PBML.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Given the risk of rapid progression, we should carefully consider the surgical indications of fluid-containing PBML.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40792-022-01444-3","type":"journal-article","created":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T04:34:59Z","timestamp":1651725299000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Rapid enlargement of pulmonary benign metastasizing leiomyoma with fluid-containing cystic change: a case report"],"prefix":"10.1186","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5047-6558","authenticated-orcid":false,"given":"Takahiro","family":"Yanagihara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naohiro","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Kikuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukinobu","family":"Goto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Ichimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,5]]},"reference":[{"key":"1444_CR1","doi-asserted-by":"publisher","first-page":"8","DOI":"10.21037\/jtd.2016.06.61","volume":"8","author":"A Ottlakan","year":"2016","unstructured":"Ottlakan A, Borda B, Lazar G, Tiszlavicz L, Furak J. Treatment decision based on the biological behavior of pulmonary benign metastasizing leiomyoma. J Thorac Dis. 2016;8:8.","journal-title":"J Thorac Dis"},{"key":"1444_CR2","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.clinimag.2010.11.003","volume":"35","author":"M Ogawa","year":"2011","unstructured":"Ogawa M, Hara M, Ozawa Y, Moriyama S, Yano M, Shimizu S, et al. Benign metastasizing leiomyoma of the lung with malignant transformation mimicking mediastinal tumor. Clin Imaging. 2011;35:5.","journal-title":"Clin Imaging"},{"key":"1444_CR3","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/0003-4975(93)90465-T","volume":"56","author":"G Gotti","year":"1993","unstructured":"Gotti G, Haid MM, Paladini P, Di Bisceglie M, Volterrani L, Sforza V. Pedunculated pulmonary leiomyoma with large cyst formation. 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Malignant transformation of pulmonary benign metastasizing leiomyoma. Korean J Thorac Cardiovasc Surg. 2017;50:1.","journal-title":"Korean J Thorac Cardiovasc Surg"},{"key":"1444_CR7","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s10147-010-0156-4","volume":"16","author":"M Mizuno","year":"2011","unstructured":"Mizuno M, Nawa A, Nakanishi T, Yatabe Y. Clinical benefit of endocrine therapy for benign metastasizing leiomyoma. Int J Clin Oncol. 2011;16:5.","journal-title":"Int J Clin Oncol"},{"key":"1444_CR8","first-page":"7","volume":"99","author":"EI Lewis","year":"2012","unstructured":"Lewis EI, Chason RJ, DeCherney AH, Armstrong A, Elkas J, Venkatesan AM. Novel hormone treatment of benign metastasizing leiomyoma: an analysis of five cases and literature review. Fertil Steril. 2012;99:7.","journal-title":"Fertil Steril"},{"key":"1444_CR9","doi-asserted-by":"publisher","first-page":"e00150","DOI":"10.1016\/j.crwh.2019.e00150","volume":"24","author":"A Al Khader","year":"2019","unstructured":"Al Khader A, Nsour E, Abdallat AN. Perinodular hydropic degeneration in uterine leiomyoma causing rapid enlargement and mimicking a myxoid smooth muscle tumor: case report of a diagnostic challenge. Case Rep Womens Health. 2019;24:e00150.","journal-title":"Case Rep Womens Health"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-022-01444-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40792-022-01444-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-022-01444-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,5]],"date-time":"2022-05-05T04:35:29Z","timestamp":1651725329000},"score":1,"resource":{"primary":{"URL":"https:\/\/surgicalcasereports.springeropen.com\/articles\/10.1186\/s40792-022-01444-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,5]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["1444"],"URL":"https:\/\/doi.org\/10.1186\/s40792-022-01444-3","relation":{},"ISSN":["2198-7793"],"issn-type":[{"value":"2198-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,5]]},"assertion":[{"value":"14 March 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"We obtained written informed consent from the patient for publication of this case report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have no conflicts of interests to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"84"}}