{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:53:48Z","timestamp":1770882828669,"version":"3.50.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["surg case rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Indocyanine green fluorescence angiography, a validated noninvasive imaging technique, is used to assess tissue vascularization. Here, we report three infant patients who underwent intraoperative indocyanine green fluorescence angiography and suffered from postoperative complications caused by the lack of weak fluorescent intestinal resection and assessed residual intestinal perfusion.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We observed the clinical characteristics and operative findings of patients treated from January 2022 to December 2022. Indocyanine green (0.5\u00a0mg\/kg) was intravenously injected. The first patient was a 29-day-old girl with surgical necrotizing enterocolitis who underwent intraoperative indocyanine green fluorescence angiography at the first- and second-look operations. The proximal jejunum was difficult to diagnose to detect blood flow during the second-look operation. The second patient was a 32-day-old boy with surgical necrotizing enterocolitis. A part of the antimesenteric mucosa of the patient that exhibited weak fluorescence was preserved; however, it formed postoperative hematomas. The third patient was a 30-day-old boy with midgut volvulus. Weak fluorescence in the intestinal wall was observed 5\u00a0cm of the small intestine from the ileocecal valve was preserved, but it formed a stricture, and the patient underwent ileocecal resection after 30\u00a0days.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Weak fluorescence in the intestine in infants by performing indocyanine green fluorescence angiography is associated with a high risk of non-recovering ischemic lesions and postoperative complications.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40792-024-01885-y","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T03:35:37Z","timestamp":1713929737000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes of nonrejection in weakly fluorescent intestine detected by indocyanine green fluorescence angiography: a case series of infants"],"prefix":"10.1186","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9366-361X","authenticated-orcid":false,"given":"Naoki","family":"Hashizume","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Yoneda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genta","family":"Ozeki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michimasa","family":"Fujiogi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motohiro","family":"Kano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Ishimaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Kanamori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Fujino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"issue":"1","key":"1885_CR1","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s10151-017-1731-8","volume":"22","author":"R Blanco-Colino","year":"2018","unstructured":"Blanco-Colino R, Espin-Basany E. Intraoperative use of ICG fluorescence imaging to reduce the risk of anastomotic leakage in colorectal surgery: a systematic review and meta-analysis. Tech Coloproctol. 2018;22(1):15\u201323.","journal-title":"Tech Coloproctol"},{"issue":"8","key":"1885_CR2","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.1016\/j.jpedsurg.2022.10.045","volume":"58","author":"EA Breuking","year":"2023","unstructured":"Breuking EA, et al. Safety and feasibility of indocyanine green fluorescence angiography in pediatric gastrointestinal surgery: a systematic review. J Pediatr Surg. 2023;58(8):1534\u201342.","journal-title":"J Pediatr Surg"},{"issue":"4","key":"1885_CR3","doi-asserted-by":"publisher","first-page":"689","DOI":"10.3390\/children10040689","volume":"10","author":"A Preziosi","year":"2023","unstructured":"Preziosi A, Paraboschi I, Giuliani S. Evaluating the development status of fluorescence-guided surgery (FGS) in pediatric surgery using the idea, development, exploration, assessment, and long-term study (IDEAL) framework. Children. 2023;10(4):689.","journal-title":"Children"},{"key":"1885_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjpso.2023.100005","volume":"3","author":"PHY Chung","year":"2023","unstructured":"Chung PHY, et al. ICG fluorescence angiography is useful in guiding intra-operative surgical decision making in necrotizing enterocolitis. J Pediatr Surg Open. 2023;3: 100005.","journal-title":"J Pediatr Surg Open"},{"issue":"8","key":"1885_CR5","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.3390\/cancers11081215","volume":"11","author":"Y Yamada","year":"2019","unstructured":"Yamada Y, et al. Fluorescence-guided surgery for hepatoblastoma with indocyanine green. Cancers. 2019;11(8):1215.","journal-title":"Cancers"},{"key":"1885_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjpso.2023.100075","volume":"4","author":"C Shirota","year":"2023","unstructured":"Shirota C, et al. Application of indocyanine green fluorescence imaging navigation in pediatric surgery: a single-center review. J Pediatr Surg Open. 2023;4: 100075.","journal-title":"J Pediatr Surg Open"},{"issue":"12","key":"1885_CR7","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1002\/bjs.7698","volume":"98","author":"A Matsui","year":"2011","unstructured":"Matsui A, et al. Predicting the survival of experimental ischaemic small bowel using intraoperative near-infrared fluorescence angiography. Br J Surg. 2011;98(12):1725\u201334.","journal-title":"Br J Surg"},{"issue":"4","key":"1885_CR8","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1007\/s00423-016-1531-z","volume":"402","author":"N Nerup","year":"2017","unstructured":"Nerup N, et al. Quantification of fluorescence angiography in a porcine model. Langenbecks Arch Surg. 2017;402(4):655\u201362.","journal-title":"Langenbecks Arch Surg"},{"issue":"5","key":"1885_CR9","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1016\/j.jpedsurg.2013.03.067","volume":"48","author":"Y Iinuma","year":"2013","unstructured":"Iinuma Y, et al. Intraoperative near-infrared indocyanine green fluorescence angiography (NIR-ICG AG) can predict delayed small bowel stricture after ischemic intestinal injury: report of a case. J Pediatr Surg. 2013;48(5):1123\u20138.","journal-title":"J Pediatr Surg"},{"issue":"4","key":"1885_CR10","doi-asserted-by":"publisher","first-page":"2245","DOI":"10.1007\/s00464-021-08973-2","volume":"36","author":"SH Emile","year":"2022","unstructured":"Emile SH, Khan SM, Wexner SD. Impact of change in the surgical plan based on indocyanine green fluorescence angiography on the rates of colorectal anastomotic leak: a systematic review and meta-analysis. Surg Endosc. 2022;36(4):2245\u201357.","journal-title":"Surg Endosc"}],"container-title":["Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-024-01885-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40792-024-01885-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40792-024-01885-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T03:40:25Z","timestamp":1713930025000},"score":1,"resource":{"primary":{"URL":"https:\/\/surgicalcasereports.springeropen.com\/articles\/10.1186\/s40792-024-01885-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,24]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["1885"],"URL":"https:\/\/doi.org\/10.1186\/s40792-024-01885-y","relation":{},"ISSN":["2198-7793"],"issn-type":[{"value":"2198-7793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,24]]},"assertion":[{"value":"28 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The ethics committee of the National Center for Child Health and Development approved this study (Approval No. 2022-135). All participants signed an informed consent statement prior to participation and obtained in the form of an opt-out form on the website. Those who rejected were excluded from the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All participants signed an informed consent statement prior to participation and obtained in the form of an opt-out form on the website. Those who rejected were excluded from the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no known competing financial interests or personal relationships that could have influenced the work reported in this paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"97"}}