{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T21:57:31Z","timestamp":1784584651477,"version":"3.55.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["surg case rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Gallbladder cysts are rare diseases with very few reported cases, and no clinical or histological definition has been established. Furthermore, cases of giant cysts outside the gallbladder wall are extremely rare. We report a rare case of giant gallbladder cyst with acute cholecystitis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>An 85-year-old woman with appetite loss and right lower abdominal pain lasting 2\u00a0days presented to our hospital. At first, the patient\u2019s abdominal pain was mild to moderate with no fever. Blood tests revealed a white blood cell count of 10,950\/mm<jats:sup>3<\/jats:sup>, and the C-reactive protein (CRP) level was 14.35\u00a0mg\/dl. A contrast-enhanced computed tomography (CT) scan of the abdomen revealed a grossly distended gallbladder (14.5\u2009\u00d7\u200914.5\u2009\u00d7\u20098.7\u00a0cm) with an incarcerated stone in the cystic duct. The patient was treated by percutaneous transhepatic gallbladder drainage (PTGBD) with 735\u00a0ml of drainage fluid. Oral contrast magnetic resonance cholangiopancreatography (MRCP) revealed that gallbladder swelling remained (14.0\u2009\u00d7\u20096.5\u00a0cm) 3\u00a0days after PTGBD. We performed laparoscopic cholecystectomy 6\u00a0days after PTGBD. Because of the severe adhesion around the junction of the cystic and common bile ducts, we performed open cholecystectomy.<\/jats:p>\n                <jats:p>The resected specimen was 14\u2009\u00d7\u200911\u00a0cm in size and consisted of a gallbladder (6\u2009\u00d7\u20097\u00a0cm) with a stone (2.4\u2009\u00d7\u20091.8\u00a0cm) in the gallbladder and a large cystic lesion (18\u2009\u00d7\u200918\u00a0cm) outside the gallbladder wall. The cystic lesion had a wall thickness of 6 to 12\u00a0mm and internal septal structures and contained hemorrhagic and necrotic tissue.<\/jats:p>\n                <jats:p>Histological examination revealed that the specimens showed a mildly swollen gallbladder and a cystic lesion on the outside of the gallbladder wall, adjacent to the gallbladder wall, with wall thickening and inflammation. The cystic lesion suggested gallbladder duplication, gallbladder diverticulum or extension of the Rokitansky-Aschoff sinus (RAS). There was no malignancy. The patient\u2019s postoperative course was uneventful, and she was discharged 5\u00a0days after the operation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>We present a very rare case of giant gallbladder cyst with acute cholecystitis revealed by cholecystectomy.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40792-024-02021-6","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T07:02:47Z","timestamp":1726729367000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Giant gallbladder cyst with acute cholecystitis: a case report"],"prefix":"10.1186","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3353-6244","authenticated-orcid":false,"given":"Takahiro","family":"Terashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohjiro","family":"Shirabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichi","family":"Inokuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Tsutsumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Ikebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshio","family":"Bandoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpei","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shogo","family":"Urabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tohru","family":"Utsunomiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,19]]},"reference":[{"key":"2021_CR1","doi-asserted-by":"publisher","first-page":"23","DOI":"10.5833\/jjgs.36.23","volume":"36","author":"N Aoyanagi","year":"2003","unstructured":"Aoyanagi N, Watanabe M, Hiraishi M, et al. 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