{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T17:17:57Z","timestamp":1775841477128,"version":"3.50.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Nutr"],"DOI":"10.1186\/s40795-024-00943-w","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T09:02:19Z","timestamp":1729501339000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The association of fructose and fiber consumption and physical activity with non-alcoholic fatty liver disease in children and adolescents: a cross-sectional study"],"prefix":"10.1186","volume":"10","author":[{"given":"Camellia","family":"Akhgarjand","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahdieh","family":"Entezarian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simin","family":"Samavat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aryan","family":"Tavakoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliarash","family":"Anoushirvani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Golaleh","family":"Asghari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emad","family":"Yusbashian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooneh","family":"Dehghan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parvin","family":"mirmiran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Imani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,21]]},"reference":[{"issue":"2","key":"943_CR1","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1097\/MPG.0000000000001482","volume":"64","author":"MB Vos","year":"2017","unstructured":"Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, et al. NASPGHAN clinical practice guideline for the diagnosis and treatment of nonalcoholic fatty liver disease in children: recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). J Pediatr Gastroenterol Nutr. 2017;64(2):319\u201334.","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"4","key":"943_CR2","first-page":"487","volume":"25","author":"A Salehisahlabadi","year":"2018","unstructured":"Salehisahlabadi A, Jadid H. The prevalence of non-alcoholic fatty liver disease in Iranian children and adolescents: a systematic review and meta-analysis. J Sabzevar Univ Med Sci. 2018;25(4):487\u201394.","journal-title":"J Sabzevar Univ Med Sci"},{"issue":"1","key":"943_CR3","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1002\/hep.28431","volume":"64","author":"ZM Younossi","year":"2016","unstructured":"Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease\u2014meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73\u201384.","journal-title":"Hepatology"},{"issue":"9","key":"943_CR4","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1038\/s41575-019-0169-z","volume":"16","author":"V Nobili","year":"2019","unstructured":"Nobili V, Alisi A, Valenti L, Miele L, Feldstein AE, Alkhouri N. NAFLD in children: new genes, new diagnostic modalities and new drugs. Nat Reviews Gastroenterol Hepatol. 2019;16(9):517\u201330.","journal-title":"Nat Reviews Gastroenterol Hepatol"},{"issue":"2","key":"943_CR5","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.cld.2015.10.003","volume":"20","author":"NP Goyal","year":"2016","unstructured":"Goyal NP, Schwimmer JB. The progression and natural history of pediatric nonalcoholic fatty liver disease. Clin Liver Dis. 2016;20(2):325\u201338.","journal-title":"Clin Liver Dis"},{"issue":"5","key":"943_CR6","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.1002\/hep.28785","volume":"64","author":"ZM Younossi","year":"2016","unstructured":"Younossi ZM, Blissett D, Blissett R, Henry L, Stepanova M, Younossi Y, et al. The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe. Hepatology. 2016;64(5):1577\u201386.","journal-title":"Hepatology"},{"issue":"5","key":"943_CR7","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1016\/j.jhep.2018.01.019","volume":"68","author":"T Jensen","year":"2018","unstructured":"Jensen T, Abdelmalek MF, Sullivan S, Nadeau KJ, Green M, Roncal C, et al. Fructose and sugar: a major mediator of non-alcoholic fatty liver disease. J Hepatol. 2018;68(5):1063\u201375.","journal-title":"J Hepatol"},{"key":"943_CR8","unstructured":"Haley S, Reed J, Lin B-H, Cook AJEORS. Sweetener consumption in the United States: distribution by demographic and product characteristics. 2005:1\u201319."},{"issue":"3","key":"943_CR9","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3390\/nu9030230","volume":"9","author":"P Jegatheesan","year":"2017","unstructured":"Jegatheesan P, De Bandt J-P. Fructose and NAFLD: the multifaceted aspects of fructose metabolism. Nutrients. 2017;9(3):230.","journal-title":"Nutrients"},{"key":"943_CR10","doi-asserted-by":"publisher","first-page":"1038435","DOI":"10.3389\/fpubh.2022.1038435","volume":"10","author":"Y Zhu","year":"2022","unstructured":"Zhu Y, Yang H, Zhang Y, Rao S, Mo Y, Zhang H, et al. Dietary fiber intake and non-alcoholic fatty liver disease: the mediating role of obesity. Front Public Health. 2022;10:1038435.","journal-title":"Front Public Health"},{"issue":"4","key":"943_CR11","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/j.jhep.2017.05.016","volume":"67","author":"M Romero-G\u00f3mez","year":"2017","unstructured":"Romero-G\u00f3mez M, Zelber-Sagi S, Trenell M. Treatment of NAFLD with diet, physical activity and exercise. J Hepatol. 2017;67(4):829\u201346.","journal-title":"J Hepatol"},{"issue":"3","key":"943_CR12","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1001\/jama.2018.20579","volume":"321","author":"JB Schwimmer","year":"2019","unstructured":"Schwimmer JB, Ugalde-Nicalo P, Welsh JA, Angeles JE, Cordero M, Harlow KE, et al. Effect of a low free sugar diet vs usual diet on nonalcoholic fatty liver disease in adolescent boys: a randomized clinical trial. JAMA. 2019;321(3):256\u201365.","journal-title":"JAMA"},{"issue":"2","key":"943_CR13","first-page":"241","volume":"6","author":"V Nobili","year":"2008","unstructured":"Nobili V, Alisi A, Panera N, Agostoni C. Low birth weight and catch-up-growth associated with metabolic syndrome: a ten year systematic review. Pediatr Endocrinol Reviews: PER. 2008;6(2):241\u20137.","journal-title":"Pediatr Endocrinol Reviews: PER"},{"issue":"2","key":"943_CR14","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.pcad.2018.01.013","volume":"61","author":"M Medrano","year":"2018","unstructured":"Medrano M, Cadenas-Sanchez C, Alvarez-Bueno C, Cavero-Redondo I, Ruiz JR, Ortega FB, et al. Evidence-based exercise recommendations to reduce hepatic fat content in youth-a systematic review and meta-analysis. Prog Cardiovasc Dis. 2018;61(2):222\u201331.","journal-title":"Prog Cardiovasc Dis"},{"issue":"4","key":"943_CR15","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1038\/ejcn.2014.8","volume":"68","author":"S Chiu","year":"2014","unstructured":"Chiu S, Sievenpiper J, De Souza R, Cozma A, Mirrahimi A, Carleton A, et al. Effect of fructose on markers of non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of controlled feeding trials. Eur J Clin Nutr. 2014;68(4):416\u201323.","journal-title":"Eur J Clin Nutr"},{"issue":"5","key":"943_CR16","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1053\/j.gastro.2013.07.012","volume":"145","author":"RD Johnston","year":"2013","unstructured":"Johnston RD, Stephenson MC, Crossland H, Cordon SM, Palcidi E, Cox EF, et al. No difference between high-fructose and high-glucose diets on liver triacylglycerol or biochemistry in healthy overweight men. Gastroenterology. 2013;145(5):1016\u201325. e2.","journal-title":"Gastroenterology"},{"issue":"3","key":"943_CR17","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1093\/ajcn\/82.3.523","volume":"82","author":"L Azadbakht","year":"2005","unstructured":"Azadbakht L, Mirmiran P, Esmaillzadeh A, Azizi F. Dairy consumption is inversely associated with the prevalence of the metabolic syndrome in tehranian adults\u2013. Am J Clin Nutr. 2005;82(3):523\u201330.","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"943_CR18","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1475-2891-10-27","volume":"10","author":"T Kobayashi","year":"2011","unstructured":"Kobayashi T, Kamimura M, Imai S, Toji C, Okamoto N, Fukui M, et al. Reproducibility and validity of the food frequency questionnaire for estimating habitual dietary intake in children and adolescents. Nutr J. 2011;10(1):27.","journal-title":"Nutr J"},{"key":"943_CR19","volume-title":"Food composition table of Iran","author":"M Azar","year":"1980","unstructured":"Azar M, Sarkisian E. Food composition table of Iran. Tehran: National Nutrition and Food Research Institute, Shaheed Beheshti University; 1980."},{"issue":"6","key":"943_CR20","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1097\/00005768-200006000-00013","volume":"32","author":"A Vuillemin","year":"2000","unstructured":"Vuillemin A, Oppert J-M, Guillemin F, Essermeant L, Fontvieille A-M, Galan P, et al. Self-administered questionnaire compared with interview to assess past-year physical activity. Med Sci Sports Exerc. 2000;32(6):1119\u201324.","journal-title":"Med Sci Sports Exerc"},{"issue":"4","key":"943_CR21","doi-asserted-by":"publisher","first-page":"401","DOI":"10.2337\/diacare.13.4.401","volume":"13","author":"AM Kriska","year":"1990","unstructured":"Kriska AM, Knowler WC, LaPorte RE, Drash AL, Wing RR, Blair SN, et al. Development of questionnaire to examine relationship of physical activity and diabetes in Pima indians. Diabetes Care. 1990;13(4):401\u201311.","journal-title":"Diabetes Care"},{"issue":"3","key":"943_CR22","doi-asserted-by":"publisher","first-page":"e65","DOI":"10.1016\/j.amepre.2018.10.012","volume":"56","author":"RR Pate","year":"2019","unstructured":"Pate RR, Dowda M, Dishman RK, Colabianchi N, Saunders RP, McIver KL. Change in children\u2019s physical activity: predictors in the transition from elementary to middle school. Am J Prev Med. 2019;56(3):e65\u201373.","journal-title":"Am J Prev Med"},{"issue":"8","key":"943_CR23","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1249\/MSS.0b013e31821ece12","volume":"43","author":"BE Ainsworth","year":"2011","unstructured":"Ainsworth BE, Haskell WL, Herrmann SD, Meckes N, Bassett DR Jr, Tudor-Locke C, et al. 2011 Compendium of Physical activities: a second update of codes and MET values. Med Sci Sports Exerc. 2011;43(8):1575\u201381.","journal-title":"Med Sci Sports Exerc"},{"key":"943_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2458-14-461","volume":"14","author":"PF Saint-Maurice","year":"2014","unstructured":"Saint-Maurice PF, Welk GJ, Beyler NK, Bartee RT, Heelan KA. Calibration of self-report tools for physical activity research: the physical activity questionnaire (PAQ). BMC Public Health. 2014;14:1\u20139.","journal-title":"BMC Public Health"},{"issue":"24","key":"943_CR25","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","volume":"54","author":"FC Bull","year":"2020","unstructured":"Bull FC, Al-Ansari SS, Biddle S, Borodulin K, Buman MP, Cardon G, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. Br J Sports Med. 2020;54(24):1451\u201362.","journal-title":"Br J Sports Med"},{"key":"943_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12966-017-0525-8","volume":"14","author":"MS Tremblay","year":"2017","unstructured":"Tremblay MS, Aubert S, Barnes JD, Saunders TJ, Carson V, Latimer-Cheung AE, et al. Sedentary behavior research network (SBRN)\u2013terminology consensus project process and outcome. Int J Behav Nutr Phys Activity. 2017;14:1\u201317.","journal-title":"Int J Behav Nutr Phys Activity"},{"key":"943_CR27","doi-asserted-by":"publisher","first-page":"2797","DOI":"10.1007\/s40279-018-0987-0","volume":"48","author":"LM Hidding","year":"2018","unstructured":"Hidding LM, Chinapaw MJ, van Poppel MN, Mokkink LB, Altenburg TM. An updated systematic review of childhood physical activity questionnaires. Sports Med. 2018;48:2797\u2013842.","journal-title":"Sports Med"},{"key":"943_CR28","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1007\/s40279-016-0663-1","volume":"47","author":"DR Bassett","year":"2017","unstructured":"Bassett DR, Toth LP, LaMunion SR, Crouter SE. Step counting: a review of measurement considerations and health-related applications. Sports Med. 2017;47:1303\u201315.","journal-title":"Sports Med"},{"issue":"1","key":"943_CR29","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1093\/jn\/nxx008","volume":"148","author":"MO Weickert","year":"2018","unstructured":"Weickert MO, Pfeiffer AF. Impact of dietary fiber consumption on insulin resistance and the prevention of type 2 diabetes. J Nutr. 2018;148(1):7\u201312.","journal-title":"J Nutr"},{"key":"943_CR30","doi-asserted-by":"crossref","unstructured":"Bozic D, Podrug K, Mikolasevic I, Grgurevic I. Ultrasound methods for the Assessment of Liver steatosis: a critical Appraisal. Diagnostics (Basel Switzerland). 2022;12(10).","DOI":"10.3390\/diagnostics12102287"},{"issue":"6","key":"943_CR31","doi-asserted-by":"publisher","first-page":"1961","DOI":"10.1002\/hep.23535","volume":"51","author":"MF Abdelmalek","year":"2010","unstructured":"Abdelmalek MF, Suzuki A, Guy C, Unalp-Arida A, Colvin R, Johnson RJ, et al. Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. Hepatology. 2010;51(6):1961\u201371.","journal-title":"Hepatology"},{"key":"943_CR32","doi-asserted-by":"crossref","unstructured":"Coronati M, Baratta F, Pastori D, Ferro D, Angelico F, Del Ben M. Added Fructose in non-alcoholic fatty liver Disease and in metabolic syndrome: a narrative review. Nutrients. 2022;14(6).","DOI":"10.3390\/nu14061127"},{"issue":"3","key":"943_CR33","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1097\/MOL.0b013e3283613bca","volume":"24","author":"KL Stanhope","year":"2013","unstructured":"Stanhope KL, Schwarz J-M, Havel PJ. Adverse metabolic effects of dietary fructose: results from the recent epidemiological, clinical, and mechanistic studies. Curr Opin Lipidol. 2013;24(3):198\u2013206.","journal-title":"Curr Opin Lipidol"},{"issue":"1","key":"943_CR34","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1194\/jlr.M800156-JLR200","volume":"50","author":"S Ghoshal","year":"2009","unstructured":"Ghoshal S, Witta J, Zhong J, De Villiers W, Eckhardt E. Chylomicrons promote intestinal absorption of lipopolysaccharides. J Lipid Res. 2009;50(1):90\u20137.","journal-title":"J Lipid Res"},{"issue":"5","key":"943_CR35","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1038\/nrgastro.2013.34","volume":"10","author":"GC Farrell","year":"2013","unstructured":"Farrell GC, Wong VW-S, Chitturi S. NAFLD in Asia\u2014as common and important as in the West. Nat Reviews Gastroenterol Hepatol. 2013;10(5):307\u201318.","journal-title":"Nat Reviews Gastroenterol Hepatol"},{"issue":"2","key":"943_CR36","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1093\/ajcn\/76.2.390","volume":"76","author":"NM McKeown","year":"2002","unstructured":"McKeown NM, Meigs JB, Liu S, Wilson PW, Jacques PF. Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham offspring study. Am J Clin Nutr. 2002;76(2):390\u20138.","journal-title":"Am J Clin Nutr"},{"key":"943_CR37","doi-asserted-by":"crossref","unstructured":"Pe\u00f1a-Jorquera H, Cid-Jofr\u00e9 V, Landaeta-D\u00edaz L, Petermann-Rocha F, Martorell M, Zbinden-Foncea H et al. Plant-Based Nutrition: Exploring Health benefits for atherosclerosis, chronic diseases, and metabolic Syndrome-A Comprehensive Review. Nutrients. 2023;15(14).","DOI":"10.3390\/nu15143244"},{"issue":"10","key":"943_CR38","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1586\/17474124.2015.1075392","volume":"9","author":"SE Keating","year":"2015","unstructured":"Keating SE, George J, Johnson NA. The benefits of exercise for patients with non-alcoholic fatty liver disease. Expert Rev Gastroenterol Hepatol. 2015;9(10):1247\u201350.","journal-title":"Expert Rev Gastroenterol Hepatol"},{"issue":"8","key":"943_CR39","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1001\/jamainternmed.2016.3202","volume":"176","author":"H-J Zhang","year":"2016","unstructured":"Zhang H-J, He J, Pan L-L, Ma Z-M, Han C-K, Chen C-S, et al. Effects of moderate and vigorous exercise on nonalcoholic fatty liver disease: a randomized clinical trial. JAMA Intern Med. 2016;176(8):1074\u201382.","journal-title":"JAMA Intern Med"},{"issue":"1","key":"943_CR40","doi-asserted-by":"publisher","first-page":"S47","DOI":"10.1016\/j.jhep.2014.12.012","volume":"62","author":"CD Byrne","year":"2015","unstructured":"Byrne CD, Targher G. NAFLD: a multisystem disease. J Hepatol. 2015;62(1):S47\u201364.","journal-title":"J Hepatol"},{"key":"943_CR41","doi-asserted-by":"crossref","unstructured":"Chambers ES, Morrison DJ, Frost G. Control of appetite and energy intake by SCFA: what are the potential underlying mechanisms? Proceedings of the Nutrition Society. 2015;74(3):328\u2009\u2013\u200936.","DOI":"10.1017\/S0029665114001657"},{"key":"943_CR42","doi-asserted-by":"crossref","unstructured":"Long Q, Luo F, Li B, Li Z, Guo Z, Chen Z et al. Gut microbiota and metabolic biomarkers in metabolic dysfunction-associated steatotic liver disease. Hepatol Commun. 2024;8(3).","DOI":"10.1097\/HC9.0000000000000310"},{"key":"943_CR43","doi-asserted-by":"crossref","unstructured":"Choi SC, Brown J, Gong M, Ge Y, Zadeh M, Li W et al. Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice. Sci Transl Med. 2020;12(551).","DOI":"10.1126\/scitranslmed.aax2220"},{"issue":"3","key":"943_CR44","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/j.cmet.2014.02.009","volume":"19","author":"SM Solon-Biet","year":"2014","unstructured":"Solon-Biet SM, McMahon AC, Ballard JWO, Ruohonen K, Wu LE, Cogger VC, et al. The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice. Cell Metabol. 2014;19(3):418\u201330.","journal-title":"Cell Metabol"}],"container-title":["BMC Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40795-024-00943-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40795-024-00943-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40795-024-00943-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T01:03:21Z","timestamp":1729645401000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcnutr.biomedcentral.com\/articles\/10.1186\/s40795-024-00943-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,21]]},"references-count":44,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["943"],"URL":"https:\/\/doi.org\/10.1186\/s40795-024-00943-w","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3860877\/v1","asserted-by":"object"}]},"ISSN":["2055-0928"],"issn-type":[{"value":"2055-0928","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,21]]},"assertion":[{"value":"13 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The Research Institute has approved this study for Endocrine Science \/ Shahid Beheshti University of Medical Science (IR.TUMS.VCR.REC.1397.333). The parents or legal guardians of the individuals signed an informed written consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"This manuscript does not contain data from any individual person and there fore this is not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All the authors declared that they have no conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"140"}}