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This study was conducted in accordance with the protocol and with the consensus ethical principles derived from international guidelines, including the Declaration of Helsinki and Council for International Organizations of Medical Sciences International Ethical Guidelines, applicable ICH Good Clinical Practice guidelines, and applicable local and federal laws and regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The investigator or the investigator\u2019s representative explained the nature of the study to the participant or the participant\u2019s legally authorized representative and answered any questions. Participants were informed that their participation was voluntary and that study reports or publications reporting on the study would not disclose the participant\u2019s identity without specific consent. Participants wishing to participate in the study, or their legally authorized representative, signed a statement of informed consent that met the requirements of local regulations, ICH guidelines, and the research ethics board. The authorized person obtaining informed consent also signed the informed consent form and a copy was provided to the participant or the participant\u2019s legally authorized representative. Written informed consent was obtained prior to all study-related procedures.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"JRB is employed by and MJA provides consulting services for MSP Starch Products Inc., Carberry, MB, Canada. MSP Starch Products Inc. sister company McPharma Biotech holds relevant patents US11058711B2, CA3024201A1, AU2017294806A1, and provisional patent PCT\/CA2021\/051443 based on the work presented herein.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"152"}}