{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:44:55Z","timestamp":1792788295567,"version":"4.5.0"},"reference-count":38,"publisher":"XMLink","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":274,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Boryung Pharmaceutical Co., Ltd.","award":["This project was an investigator-initiated trial. This research was funded by a grant from Boryung Pharmaceutical Co., Ltd. (Seoul, Korea). The funder had no role in the study design, data collection and analysis, preparation of the manuscript, or decision to submit the manuscript."],"award-info":[{"award-number":["This project was an investigator-initiated trial. This research was funded by a grant from Boryung Pharmaceutical Co., Ltd. (Seoul, Korea). The funder had no role in the study design, data collection and analysis, preparation of the manuscript, or decision to submit the manuscript."]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Hypertens"],"DOI":"10.1186\/s40885-024-00287-4","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T20:02:09Z","timestamp":1727726529000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Real-world efficacy of fimasartan vs. other angiotensin receptor blockers in combination with calcium channel blockers: a nationwide cohort study"],"prefix":"10.5646","volume":"30","author":[{"given":"Huijin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan Soon","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bongseong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Min","family":"Rhee","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heesun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyungdo","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7950-2131","authenticated-orcid":false,"given":"Hyung-Kwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Seoul National University Hospital, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18617","published-online":{"date-parts":[[2024]]},"reference":[{"key":"10.1186\/s40885-024-00287-4_ref1","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0140-6736(21)01330-1","volume":"398","author":"","year":"2021","journal-title":"Lancet"},{"key":"10.1186\/s40885-024-00287-4_ref2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/s41569-021-00559-8","volume":"18","author":"Zhou","year":"2021","journal-title":"Nat Rev Cardiol"},{"key":"10.1186\/s40885-024-00287-4_ref3","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1161\/HYPERTENSIONAHA.119.14240","volume":"75","author":"Fuchs","year":"2020","journal-title":"Hypertension"},{"key":"10.1186\/s40885-024-00287-4_ref4","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","volume":"42","author":"Chobanian","year":"2003","journal-title":"Hypertension"},{"key":"10.1186\/s40885-024-00287-4_ref5","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1016\/S0140-6736(00)03307-9","volume":"356","author":"Neal","year":"2000","journal-title":"Lancet"},{"key":"10.1186\/s40885-024-00287-4_ref6","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1001\/jama.1997.03540330061036","volume":"277","author":"Psaty","year":"1997","journal-title":"JAMA"},{"key":"10.1186\/s40885-024-00287-4_ref7","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/jama.2013.184182","volume":"310","author":"Chow","year":"2013","journal-title":"JAMA"},{"key":"10.1186\/s40885-024-00287-4_ref8","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1524-6175.2003.00495.x","volume":"5","author":"Neutel","year":"2003","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1186\/s40885-024-00287-4_ref9","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1016\/j.jacc.2014.08.021","volume":"64","author":"Castellano","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s40885-024-00287-4_ref10","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s40264-014-0239-7","volume":"38","author":"Abraham","year":"2015","journal-title":"Drug Saf"},{"key":"10.1186\/s40885-024-00287-4_ref11","first-page":"e484","volume":"138","author":"Whelton","year":"2018","journal-title":"Circulation"},{"key":"10.1186\/s40885-024-00287-4_ref12","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1093\/eurheartj\/ehy339","volume":"39","author":"Williams","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1186\/s40885-024-00287-4_ref13","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s40885-019-0124-x","volume":"25","author":"Lee","year":"2019","journal-title":"Clin Hypertens"},{"key":"10.1186\/s40885-024-00287-4_ref14","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/j.bmcl.2011.12.116","volume":"22","author":"Kim","year":"2012","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1186\/s40885-024-00287-4_ref15","doi-asserted-by":"crossref","first-page":"335","DOI":"10.2165\/11593840-000000000-00000","volume":"11","author":"Chi","year":"2011","journal-title":"Am J Cardiovasc Drugs"},{"key":"10.1186\/s40885-024-00287-4_ref16","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.clinthera.2013.06.021","volume":"35","author":"Lee","year":"2013","journal-title":"Clin Ther"},{"key":"10.1186\/s40885-024-00287-4_ref17","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.clinthera.2023.01.005","volume":"45","author":"Oh","year":"2023","journal-title":"Clin Ther"},{"key":"10.1186\/s40885-024-00287-4_ref18","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1007\/s40265-016-0592-1","volume":"76","author":"Lee","year":"2016","journal-title":"Drugs"},{"key":"10.1186\/s40885-024-00287-4_ref19","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s40885-023-00243-8","volume":"29","author":"Kim","year":"2023","journal-title":"Clin Hypertens"},{"key":"10.1186\/s40885-024-00287-4_ref20","doi-asserted-by":"crossref","first-page":"15785","DOI":"10.1038\/s41598-022-19895-x","volume":"12","author":"Choi","year":"2022","journal-title":"Sci Rep"},{"key":"10.1186\/s40885-024-00287-4_ref21","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.2337\/dc21-2299","volume":"45","author":"Park","year":"2022","journal-title":"Diabetes Care"},{"key":"10.1186\/s40885-024-00287-4_ref22","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1177\/2047487319889714","volume":"27","author":"Park","year":"2020","journal-title":"Eur J Prev Cardiol"},{"key":"10.1186\/s40885-024-00287-4_ref23","doi-asserted-by":"crossref","first-page":"754","DOI":"10.4070\/kcj.2020.0171","volume":"50","author":"Choi","year":"2020","journal-title":"Korean Circ J"},{"key":"10.1186\/s40885-024-00287-4_ref24","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1161\/HYPERTENSIONAHA.120.16659","volume":"77","author":"Lee","year":"2021","journal-title":"Hypertension"},{"key":"10.1186\/s40885-024-00287-4_ref25","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1007\/s00392-023-02179-3","volume":"112","author":"Park","year":"2023","journal-title":"Clin Res Cardiol"},{"key":"10.1186\/s40885-024-00287-4_ref26","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.jacc.2016.11.034","volume":"69","author":"Ferdinand","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1186\/s40885-024-00287-4_ref27","volume-title":"Adherence to long-term therapies: evidence for action","year":"2003"},{"key":"10.1186\/s40885-024-00287-4_ref28","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1056\/NEJMra050100","volume":"353","author":"Osterberg","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1186\/s40885-024-00287-4_ref29","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.jash.2011.01.001","volume":"5","author":"Hill","year":"2011","journal-title":"J Am Soc Hypertens"},{"key":"10.1186\/s40885-024-00287-4_ref30","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.phrs.2017.08.015","volume":"125","author":"Burnier","year":"2017","journal-title":"Pharmacol Res"},{"key":"10.1186\/s40885-024-00287-4_ref31","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1186\/s12877-017-0621-2","volume":"17","author":"Masnoon","year":"2017","journal-title":"BMC Geriatr"},{"key":"10.1186\/s40885-024-00287-4_ref32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/1470320310370852","volume":"12","author":"Miura","year":"2011","journal-title":"J Renin Angiotensin Aldosterone Syst"},{"key":"10.1186\/s40885-024-00287-4_ref33","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.cell.2015.04.011","volume":"161","author":"Zhang","year":"2015","journal-title":"Cell"},{"key":"10.1186\/s40885-024-00287-4_ref34","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.clinthera.2012.01.024","volume":"34","author":"Lee","year":"2012","journal-title":"Clin Ther"},{"key":"10.1186\/s40885-024-00287-4_ref35","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/j.clinthera.2014.07.004","volume":"36","author":"Youn","year":"2014","journal-title":"Clin Ther"},{"key":"10.1186\/s40885-024-00287-4_ref36","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.3904\/kjim.2016.094","volume":"32","author":"Lee","year":"2017","journal-title":"Korean J Intern Med"},{"key":"10.1186\/s40885-024-00287-4_ref37","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.clinthera.2016.04.005","volume":"38","author":"Lee","year":"2016","journal-title":"Clin Ther"},{"key":"10.1186\/s40885-024-00287-4_ref38","doi-asserted-by":"crossref","first-page":"347","DOI":"10.2147\/DDDT.S231293","volume":"14","author":"Chung","year":"2020","journal-title":"Drug Des Devel Ther"}],"container-title":["Clinical Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/clinicalhypertension.org\/pdf\/10.1186\/s40885-024-00287-4","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40885-024-00287-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/clinicalhypertension.org\/DOIx.php?id=10.1186\/s40885-024-00287-4","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40885-024-00287-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/clinicalhypertension.org\/DOIx.php?id=10.1186\/s40885-024-00287-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T01:00:52Z","timestamp":1746061252000},"score":1,"resource":{"primary":{"URL":"https:\/\/clinicalhypertension.org\/DOIx.php?id=10.1186\/s40885-024-00287-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1186\/s40885-024-00287-4","relation":{},"ISSN":["2056-5909"],"issn-type":[{"value":"2056-5909","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"31 January 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study adhered to the principles of the Declaration of Helsinki and was approved by the Institutional Review Board of Seoul National University Hospital (E-2103-004-120), which waived the need for informed consent due to the use of de-identified data.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Hyung-Kwan Kim has received research grants from HK Inno. N, Johnson and Johnson, GSK, Samjin Pharm, ChongKunDang Pharm, Boryung Pharm, and JW Pharm. The authors declare no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"28"}}