{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:59:43Z","timestamp":1790963983735,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T00:00:00Z","timestamp":1766361600000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002386","name":"Cairo University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002386","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Maxillofac Plast Reconstr Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Several treatment modalities have been reported in the management of mandibular fractures using an alternative computer-guided approach through the utilization of different designs of guiding devices. However, these computer-guided methods do not always guarantee accurate anatomical bone reduction. This study aimed to assess the reduction precision of the computer-guided mandibular fracture and internal fixation using screw holes locating surgical guide, as presented earlier in the orthognathic surgery field in various studies to be applied in the field of mandibular traumatology, comparing it with the conventional approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Twenty-six patients with\n                      <jats:bold>\n                        <jats:italic>Brown<\/jats:italic>\n                      <\/jats:bold>\n                      Class III mandibular fracture, defined by a single fracture line involving the body, parasymphysis or symphysis regions, were randomly assigned to two groups for open reduction and internal fixation. The study group underwent reduction and fixation using patient-specific screw-hole locating guide and pre-bent titanium miniplates, whereas the control group received conventional reduction and fixation with intraoperatively adapted titanium miniplates. Virtual reduction of the fractured mandible was performed in all cases of both groups utilizing CT scan and mimics software. Then, the actual postoperative mandibular model was superimposed over the virtually operated mandibular model based on predefined reference points and plans to obtain dental and bony linear measurements. The recorded measures were statistically analysed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The actual postoperative mandibular model in the computer-guided group showed minimal deviation from the virtual mandibular model. While the deviation of the actual post operative model in the conventional group from the virtual model was higher, the difference in deviation between the two groups was statistically significant. The mean bony deviation was 0.09\u2009\u00b1\u20090.29\u00a0mm in the computer-guided group, versus 0.70\u2009\u00b1\u20090.33\u00a0mm in the control group\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001. The mean dental deviation was 0.05\u2009\u00b1\u20090.16\u00a0mm in the computer-guided group versus 0.56\u2009\u00b1\u20090.32\u00a0mm in the control group\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001.The mean operative time of the computer-guided group(1.49\u2009\u00b1\u20090.19)(hours) was significantly shorter than the mean operative time of control group (1.82\u2009\u00b1\u20090.37)(hours) which is statistically significant\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The use of screw-hole locating guide and pre-bent plates enhanced surgical accuracy and efficiency. It also highlighted how patient-specific design can reduce dependence on surgeon experience and standardized outcomes in complex mandibular fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>The study is registered at ClinicalTrials.gov Protocol Registration and Results System Receipt, ID: NCT05444829.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s40902-025-00495-4","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T04:25:13Z","timestamp":1766118313000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Precision of patient specific screw holes locating surgical guide and pre-bent plates osteosynthesis versus classical workflow in management of class III mandibular fracture"],"prefix":"10.1186","volume":"47","author":[{"given":"Abdallah","family":"Gaber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussein","family":"Hatem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"el","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Omara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"495_CR1","volume-title":"StatPearls","author":"G Breeland","year":"2023","unstructured":"Breeland G, Aktar A, Patel BC (2023) Anatomy, Head and Neck, Mandible. StatPearls. StatPearls Publishing"},{"issue":"1","key":"495_CR2","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.ijom.2021.02.012","volume":"51","author":"JS Brown","year":"2022","unstructured":"Brown JS, Khan A, Wareing S, Schache AG (2022) A new classification of mandibular fractures. Int J Oral Maxillofac Surg 51(1):78\u201390. https:\/\/doi.org\/10.1016\/j.ijom.2021.02.012","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"4","key":"495_CR3","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/j.jcms.2023.11.009","volume":"52","author":"H Zhuang","year":"2024","unstructured":"Zhuang H, Zhu B, Zhu L, You Y, Zhang J, Bu S (2024) Streamlining complex mandibular fracture treatment: integration of virtual surgical planning and short-segment drilling guides. J Cranio-Maxillofac Surg 52(4):397\u2013405","journal-title":"J Cranio-Maxillofac Surg"},{"key":"495_CR4","first-page":"50","volume":"1","author":"KL Gerlach","year":"2016","unstructured":"Gerlach KL, Erle A, Eckelt U, Loukota R, Luhr HG, Bos RRM (2016) 5-Surgical management of mandibular fractures. Maxillofac Surg 1:50\u201373","journal-title":"Maxillofac Surg"},{"issue":"10","key":"495_CR5","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1016\/j.bjoms.2021.05.002","volume":"59","author":"M Omara","year":"2021","unstructured":"Omara M, Ali S, Ahmed M (2021) Accuracy of midface advancement using patient-specific surgical guides and pre-bent plates versus conventional interocclusal wafers and conventional plate fixation in quadrangular Le Forte II osteotomy. A randomised controlled trial. Br J Oral Maxillofac Surg 59(10):1253\u20131258","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"2","key":"495_CR6","doi-asserted-by":"publisher","first-page":"175","DOI":"10.3758\/BF03193146","volume":"39","author":"F Faul","year":"2007","unstructured":"Faul F, Erdfelder E, Lang AG, Buchner A (2007) G* power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39(2):175\u2013191","journal-title":"Behav Res Methods"},{"key":"495_CR7","doi-asserted-by":"crossref","unstructured":"Pickrell BB, Serebrakian AT, Maricevich RS (2017) May). Mandible fractures. Seminars in plastic surgery, vol 31. Thieme Medical, pp 100\u2013107. 02","DOI":"10.1055\/s-0037-1601374"},{"issue":"4","key":"495_CR8","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1055\/s-0041-1735818","volume":"35","author":"K Panesar","year":"2021","unstructured":"Panesar K, Susarla SM (2021) Mandibular fractures: diagnosis and management. Semin Plast Surg 35(4):238\u2013249. https:\/\/doi.org\/10.1055\/s-0041-1735818","journal-title":"Semin Plast Surg"},{"issue":"2","key":"495_CR9","doi-asserted-by":"publisher","DOI":"10.1115\/1.4052901","volume":"16","author":"JF Oeding","year":"2022","unstructured":"Oeding JF, Bockman S, Chiu H, Hua C, Connor J, Slocum A (2022) A novel approach to open reduction and internal fixation of distal radius fractures utilizing a multi-degree-of-freedom traction and stabilization device. J Med Devices 16(2):021006. https:\/\/doi.org\/10.1115\/1.4052901","journal-title":"J Med Devices"},{"key":"495_CR10","doi-asserted-by":"publisher","unstructured":"Cheng YB, Yang S (2020) Zhongguo Gu shang\u2009=\u2009China journal of orthopaedics and traumatology. 33(4):367\u2013370. https:\/\/doi.org\/10.12200\/j.issn.1003-0034.2020.04.015.","DOI":"10.12200\/j.issn.1003-0034.2020.04.015"},{"issue":"5","key":"495_CR11","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1148\/rg.2016150218","volume":"36","author":"D Dreizin","year":"2016","unstructured":"Dreizin D, Nam AJ, Tirada N, Levin MD, Stein DM, Bodanapally UK, Mirvis SE, Munera F (2016) Multidetector CT of mandibular fractures, reductions, and complications: a clinically relevant primer for the radiologist. Radiographics: Rev Publication Radiological Soc North Am Inc 36(5):1539\u20131564. https:\/\/doi.org\/10.1148\/rg.2016150218","journal-title":"Radiographics: Rev Publication Radiological Soc North Am Inc"},{"issue":"7","key":"495_CR12","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006087.pub3","volume":"2013","author":"M Nasser","year":"2013","unstructured":"Nasser M, Pandis N, Fleming PS, Fedorowicz Z, Ellis E, Ali K (2013) Interventions for the management of mandibular fractures. Cochrane Database Syst Rev 2013(7):CD006087. https:\/\/doi.org\/10.1002\/14651858.CD006087.pub3","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"495_CR13","doi-asserted-by":"publisher","first-page":"3117","DOI":"10.21608\/edj.2022.142056.2128","volume":"68","author":"H Said","year":"2022","unstructured":"Said H (2022) Management of unfavorable displaced mandibular angle fracture with combined rigid and semi-rigid fixation using trans-oral and trans-buccal approaches. One year prospective clinical and radiographic study. Egypt Dent J 68(4):3117\u20133128","journal-title":"Egypt Dent J"},{"issue":"Suppl 3","key":"495_CR14","doi-asserted-by":"publisher","first-page":"S1920","DOI":"10.4103\/jpbs.jpbs_11_24","volume":"16","author":"N Gawali","year":"2024","unstructured":"Gawali N, Shah PP, Gowdar IM, Bhavsar KA, Giri D, Laddha R (2024) The evolution of digital dentistry: a comprehensive review. J Pharm Bioallied Sci 16(Suppl 3):S1920\u2013S1922. https:\/\/doi.org\/10.4103\/jpbs.jpbs_11_24","journal-title":"J Pharm Bioallied Sci"},{"key":"495_CR15","doi-asserted-by":"crossref","unstructured":"Omara M, Ali S, Alian YS, Shobair NI A Novel Intraoral Mandibular Osteotomy For Set-Back Surgery In Complex Mandibular Anatomy. Clinical oral investigations, 29(4), 215., Sakakibara H, Taniguchi A, A., Hoshi K (2025) (2025). Virtual surgical planning and augmented reality for fixation of plate during Le Fort I osteotomy. Oral and maxillofacial surgery, 29(1), 78.https:\/\/doi.org\/10.1007\/s10006-025-01374-y.","DOI":"10.1007\/s00784-025-06239-y"},{"issue":"8","key":"495_CR16","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/s1010-5182(05)80364-6","volume":"20","author":"C Krenkel","year":"1992","unstructured":"Krenkel C (1992) Axial \u201canchor\u201d screw (lag screw with biconcave washer) or \u201cslanted-screw\u201d plate for osteosynthesis of fractures of the mandibular condylar process. J Craniofac Surg 20(8):348\u2013353. https:\/\/doi.org\/10.1016\/s1010-5182(05)80364-6","journal-title":"J Craniofac Surg"},{"issue":"8","key":"495_CR17","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1016\/j.ijom.2019.01.026","volume":"48","author":"H Ji","year":"2019","unstructured":"Ji H, Du W, Xu C, Zhao Q, Ye B, Luo E (2019) Computer-assisted osteotomy guides and pre-bent titanium plates improve the planning for correction of facial asymmetry. Int J Oral Maxillofac Surg 48(8):1043\u20131050. https:\/\/doi.org\/10.1016\/j.ijom.2019.01.026","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"6","key":"495_CR18","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1053\/joms.2002.33110","volume":"60","author":"E Ellis 3rd","year":"2002","unstructured":"Ellis E 3rd, Graham J (2002) Use of a 2.0-mm locking plate\/screw system for mandibular fracture surgery. Journal of oral and maxillofacial surgery\u202f: official journal of the American Association of Oral and Maxillofacial Surgeons 60(6):642\u2013646. https:\/\/doi.org\/10.1053\/joms.2002.33110.","journal-title":"Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons"},{"key":"495_CR19","doi-asserted-by":"crossref","unstructured":"Fonseca RJ, Barber HD, Powers MP, & Frost DE. Mandibular fractures. In: Fonseca, R.J. editor. Oral and maxillofacial trauma (4th ed.). Philadelphia, PA: Elsevier Health Sciences. 2012. p. 293\u2013330.","DOI":"10.1016\/B978-1-4557-0554-2.00014-9"},{"issue":"3","key":"495_CR20","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/s0278-2391(99)90674-2","volume":"57","author":"J Potter","year":"1999","unstructured":"Potter J, Ellis E 3rd (1999) Treatment of mandibular angle fractures with a malleable noncompression miniplate. Journal of oral and maxillofacial surgery\u202f: official journal of the American Association of Oral and Maxillofacial Surgeons 57(3):288\u2013293. https:\/\/doi.org\/10.1016\/s0278-2391(99)90674-2","journal-title":"Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons"},{"issue":"1","key":"495_CR21","doi-asserted-by":"publisher","first-page":"113","DOI":"10.21608\/edj.2021.91875.1763","volume":"68","author":"M Omara","year":"2022","unstructured":"Omara M, Emara A (2022) Computer guided chin repositioning using patient specific osteotomy\/screw hole\/plate locating surgical guides. Egypt Dent J 68(1):113\u2013119. https:\/\/doi.org\/10.21608\/edj.2021.91875.1763","journal-title":"Egypt Dent J"},{"issue":"6","key":"495_CR22","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1089\/neu.2011.1794","volume":"29","author":"B Lethaus","year":"2012","unstructured":"Lethaus B, Safi Y, ter Laak-Poort M, Kloss-Brandst\u00e4tter A, Banki F, Robbenmenke C, Kessler P (2012) Cranioplasty with customized titanium and PEEK implants in a mechanical stress model. J Neurotrauma 29(6):1077\u20131083","journal-title":"J Neurotrauma"},{"issue":"4","key":"495_CR23","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.mjafi.2024.05.008","volume":"80","author":"V Saxena","year":"2024","unstructured":"Saxena V, Krishnan VG, Rangarajan H (2024) Virtual 3D planning in maxillofacial surgery\u202f: the journey so far and the way ahead. Med J Armed Forces India 80(4):392\u2013398. https:\/\/doi.org\/10.1016\/j.mjafi.2024.05.008","journal-title":"Med J Armed Forces India"},{"issue":"9","key":"495_CR24","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11092385","volume":"11","author":"A Zoabi","year":"2022","unstructured":"Zoabi A, Redenski I, Oren D, Kasem A, Zigron A, Daoud S, Moskovich L, Kablan F, Srouji S (2022) 3D printing and virtual surgical planning in oral and maxillofacial surgery. J Clin Med 11(9):2385. https:\/\/doi.org\/10.3390\/jcm11092385","journal-title":"J Clin Med"},{"issue":"10","key":"495_CR25","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.47979","volume":"15","author":"MO Alhabshi","year":"2023","unstructured":"Alhabshi MO, Aldhohayan H, BaEissa OS, Al Shehri MS, Alotaibi NM, Almubarak SK, Al Ahmari AA, Khan HA, Alowaimer HA (2023) Role of three-dimensional printing in treatment planning for orthognathic surgery: a systematic review. Cureus 15(10):e47979. https:\/\/doi.org\/10.7759\/cureus.47979","journal-title":"Cureus"},{"issue":"6","key":"495_CR26","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1007\/s11548-021-02353-w","volume":"16","author":"J Nilsson","year":"2021","unstructured":"Nilsson J, Nysj\u00f6 F, Nystr\u00f6m I, K\u00e4mpe J, Thor A (2021) Evaluation of in-house, haptic assisted surgical planning for virtual reduction of complex mandibular fractures. Int J Comput Assist Radiol Surg 16(6):1059\u20131068. https:\/\/doi.org\/10.1007\/s11548-021-02353-w","journal-title":"Int J Comput Assist Radiol Surg"},{"issue":"5","key":"495_CR27","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1097\/SCS.0000000000001773","volume":"26","author":"M el-Gengehi","year":"2015","unstructured":"el-Gengehi M, Seif SA (2015) Evaluation of the accuracy of computer-guided mandibular fracture reduction. J Craniofac Surg 26(5):1587\u20131591","journal-title":"J Craniofac Surg"}],"container-title":["Maxillofacial Plastic and Reconstructive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40902-025-00495-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40902-025-00495-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40902-025-00495-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T09:22:17Z","timestamp":1766395337000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s40902-025-00495-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,19]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["495"],"URL":"https:\/\/doi.org\/10.1186\/s40902-025-00495-4","relation":{},"ISSN":["2288-8586"],"issn-type":[{"value":"2288-8586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,19]]},"assertion":[{"value":"30 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted following the Declaration of Helsinki\u2019s guidelines for medical research, and the research ethics committee of Cairo University\u2019s Faculty of Dentistry provided a letter of clarification. All participants that were included in the study signed a written informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors affirm that all research participants and\/or their guardians signed informed consent for the publication of the images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"43"}}