{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:05:20Z","timestamp":1758704720706},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T00:00:00Z","timestamp":1727654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Retin Vitr"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>This study aims to examine vessel density changes in the optic nerve and macula following silicone oil removal (SOR) surgery in eyes with rhegmatogenous retinal detachment (RRD) at different time points by Optical Coherence Tomography Angiography (OCTA) in compared to the contralateral eye.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A total of 43 eyes from 43 patients with silicone oil in their eyes for 3\u20139 months underwent OCT-A using AngioVue and optic disc-associated vessel density (VD) and thickness, macular-associated VD and thickness, Foveal avascular zone (FAZ) area, FAZ perimeter (PERIM), Acircularity index (AI), vessel density within a 300\u00a0\u03bcm wide region of the FAZ were compared between eyes. OCTA scans were performed one week before\u00a0SOR and one month and three months after SOR.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The mean age of participants was 52.8 years (SD\u2009=\u200915.85) and a median visual acuity was\u00a00.8 (range: 0.5-1.0). Notably, male participants constituted 67.4% of the sample. The preoperative mean value BCVA (logMAR) of patients was 0.73, and 3 months post-oil removal was\u00a00.7727. Regarding optic disc parameters, RNFL thickness and vessel density (VD) measurements Peripapillary, whole disc, inside disc, and Disc Angio (superior, Nasal, inferior, temporal) did not change.<\/jats:p>\n                <jats:p>In analyzing macular thickness parameters, all of them (Whole and Fovea, parafoveal, and Perifovea) remained unchanged. Examining macular vessel density parameters revealed no significant changes across superficial and deep retinal layers. Finally, the comparison of the foveal avascular zone (FAZ) area and flow density (FD) parameters demonstrated consistent measurements with non-significant alterations observed in FAZ size (p\u2009=\u20090.6) and FD values (p\u2009=\u20090.49) over the monitored duration.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>There was no change in peripapillary VD and macular vessel density of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) after silicone oil removal.  FAZ  and full retinal thickness\u00a0 remained\u00a0stable 3 month after SOR.\u00a0<\/jats:p>\n                <jats:p><jats:italic>Clinical trial number<\/jats:italic>: Not applicable.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40942-024-00587-9","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T10:01:56Z","timestamp":1727690516000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Retinal vascular changes after Silicon Oil removal in the Eye with Rhegmatogenous Retinal detachment"],"prefix":"10.1186","volume":"10","author":[{"given":"Ali","family":"Salehi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Malekahmadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abolfazl","family":"Karimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afsaneh Naderi","family":"Beni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,9,30]]},"reference":[{"issue":"1","key":"587_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12886-020-01533-7","volume":"20","author":"E Wang","year":"2020","unstructured":"Wang E, Chen Y, Li N, Min H. Effect of silicone oil on peripapillary capillary density in patients with rhegmatogenous retinal detachment. BMC Ophthalmol. 2020;20(1):1\u20138.","journal-title":"BMC Ophthalmol"},{"issue":"3","key":"587_CR2","first-page":"151","volume":"33","author":"M Ya","year":"2020","unstructured":"Ya M, Zhu XQ, Peng XY. Macular perfusion changes and ganglion cell complex loss in silicone oil-related visual loss patients. Biomed Environ Sci. 2020;33(3):151\u20137.","journal-title":"Biomed Environ Sci"},{"key":"587_CR3","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1007\/s00417-011-1873-8","volume":"250","author":"G Morphis","year":"2012","unstructured":"Morphis G, Irigoyen C, Eleuteri A, Stappler T, Pearce I, Heimann H. Retrospective review of 50 eyes with long-term silicone oil tamponade for more than 12 months. Graefe\u2019s Archive Clin Experimental Ophthalmol. 2012;250:645\u201352.","journal-title":"Graefe\u2019s Archive Clin Experimental Ophthalmol"},{"issue":"2","key":"587_CR4","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1097\/IAE.0000000000000711","volume":"36","author":"LM Scheerlinck","year":"2016","unstructured":"Scheerlinck LM, Schellekens PA, Liem AT, Steijns D, Van Leeuwen R. Incidence, risk factors, and clinical characteristics of unexplained visual loss after intraocular silicone oil for macula-on retinal detachment. Retina. 2016;36(2):342\u201350.","journal-title":"Retina"},{"issue":"3","key":"587_CR5","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1097\/IAE.0000000000000325","volume":"35","author":"Z Shalchi","year":"2015","unstructured":"Shalchi Z, Mahroo OA, Shunmugam M, Mohamed M, Sullivan PM, Williamson TH. Spectral-domain optical coherence tomography findings in long-term silicone oil\u2013related visual loss. 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