{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:15:42Z","timestamp":1740176142688,"version":"3.37.3"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T00:00:00Z","timestamp":1572393600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T00:00:00Z","timestamp":1572393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["JA Clin Rep"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n              <jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Hemoglobin Kansas (Hb Kansas) is a rare disease with cyanosis.<\/jats:p>\n                <jats:p>We report a case of anesthetic management for a patient with an acute aortic dissection complicated by Hb Kansas.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We encountered a 62-year-old male, surgical patient with an acute aortic dissection complicated by postoperative Hb Kansas. During anesthesia, his arterial oxygen saturation was low, while the partial pressure of arterial oxygen was within the normal range. The patient underwent ascending aortic replacement under hypothermic circulation arrest with a bladder temperature of 22\u2009\u00b0C after introducing cardiopulmonary bypass. The patient was then referred to the hematology department for detailed examination and was diagnosed as having Hb Kansas through genetic analysis at 2\u00a0months after surgery.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Except for apparent cyanosis, Hb Kansas causes no clinical problems because the delivery of oxygen to peripheral tissues may be enhanced for such patients. When we perform anesthetic management for cyanosis patients with unknown causes, it is necessary to consider the oxygen supply-demand balance.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40981-019-0293-3","type":"journal-article","created":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T23:03:14Z","timestamp":1572476594000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anesthetic management of a surgical patient with an acute aortic dissection complicated by hemoglobin Kansas"],"prefix":"10.1186","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5956-6047","authenticated-orcid":false,"given":"Takashi","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,10,30]]},"reference":[{"key":"293_CR1","doi-asserted-by":"publisher","first-page":"207","DOI":"10.2169\/internalmedicine.56.7349","volume":"56","author":"Y Nagayama","year":"2017","unstructured":"Nagayama Y, Yoshida M, Kohyama T, Matsui K. Hemoglobin Kansas as a rare cause of cyanosis: a case report and review of the literature. Intern Med. 2017;56:207\u20139.","journal-title":"Intern Med"},{"key":"293_CR2","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1056\/NEJM196910232811701","volume":"281","author":"G Stamatoyannopoulos","year":"1969","unstructured":"Stamatoyannopoulos G, Parer JT, Finch CA. Physiologic implications of a hemoglobin with decreased oxygen affinity (hemoglobinSeattle). N Engl J Med. 1969;281:916\u20139.","journal-title":"N Engl J Med"},{"key":"293_CR3","doi-asserted-by":"publisher","first-page":"1826","DOI":"10.1172\/JCI104406","volume":"40","author":"KR Reissmann","year":"1961","unstructured":"Reissmann KR, Ruth WE, Nomura T. A human hemoglobin with lowered oxygen affinity and impaired heme-heme interactions. J Clin Invest. 1961;40:1826\u201333.","journal-title":"J Clin Invest"},{"key":"293_CR4","first-page":"824","volume":"66","author":"H Kobayashi","year":"2017","unstructured":"Kobayashi H, Iga S, Motohashi Y, Kumano N, Nanba K, Saeki S. General anesthesia for an infant with low oxygen affinity hemoglobinopathy. Masui. 2017;66:824\u20136.","journal-title":"Masui"},{"key":"293_CR5","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1213\/XAA.0000000000000959","volume":"12","author":"YS Varnado-Rhodes","year":"2019","unstructured":"Varnado-Rhodes YS. Clinical cyanosis in a patient presenting for outpatient colonoscopy: a case report of hemoglobin Kansas. A&A Practice. 2019;12:433\u20135.","journal-title":"A&A Practice"}],"container-title":["JA Clinical Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40981-019-0293-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s40981-019-0293-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s40981-019-0293-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:08:56Z","timestamp":1603930136000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaclinicalreports.springeropen.com\/articles\/10.1186\/s40981-019-0293-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,30]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["293"],"URL":"https:\/\/doi.org\/10.1186\/s40981-019-0293-3","relation":{},"ISSN":["2363-9024"],"issn-type":[{"type":"electronic","value":"2363-9024"}],"subject":[],"published":{"date-parts":[[2019,10,30]]},"assertion":[{"value":"13 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 October 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from all subjects for publication of this case report.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"69"}}