{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T12:17:37Z","timestamp":1649074657136},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,3,16]],"date-time":"2020-03-16T00:00:00Z","timestamp":1584316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,3,16]],"date-time":"2020-03-16T00:00:00Z","timestamp":1584316800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["JA Clin Rep"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Cancer is a risk factor for perioperative deep venous thrombosis and pulmonary embolism (DVT\/PE). However, there is a paucity of data on non-malignant digestive diseases. In this study, we aimed to investigate the incidence of DVT\/PE among patients, following surgery for acute appendicitis and other digestive diseases.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We retrospectively reviewed the records of patients who underwent surgical procedures involving the digestive system between April 2018 and March 2019 attended by anesthesiologists (<jats:italic>n<\/jats:italic> = 536).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>DVT\/PE developed in seven patients (7\/77, 9.1%, 95% confidence interval [CI] 3.7\u201317.8%) after surgery for acute appendicitis, and in six patients (6\/83, 7.2%, 95%CI 2.7\u201315.1%) after elective surgery for colorectal cancer. Among the acute appendicitis group, six patients (6\/30 20.0%) with complicated appendicitis (gangrenous or perforated appendicitis), and one patient (1\/47 2.1%) with simple appendicitis showed postoperative DVT\/PE. Patients with complicated appendicitis had a higher risk of DVT\/PE than those with simple appendicitis with an odds ratio of 11.5 (95%CI 1.3\u2013101.1).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Although patients with acute appendicitis lack three of the risk factors for DVT\/PE (cancer, long operative time, and older age), their 95% CI for the incidence of DVT\/PE was comparable to that of patients undergoing elective surgery for colorectal cancer. Therefore, caution must be exercised during the perioperative period for preventing DVT\/PE.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40981-020-00328-5","type":"journal-article","created":{"date-parts":[[2020,3,16]],"date-time":"2020-03-16T18:02:59Z","timestamp":1584381779000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidence of postsurgical pulmonary embolism and deep venous thrombosis: a single-center retrospective observational study"],"prefix":"10.1186","volume":"6","author":[{"given":"Hitomi","family":"Otsuka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Izumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eriko","family":"Ota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriaki","family":"Mochizuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,3,16]]},"reference":[{"issue":"2","key":"328_CR1","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1160\/TH16-08-0615","volume":"117","author":"C Ay","year":"2017","unstructured":"Ay C, Pabinger I, Cohen AT. Cancer-associated venous thromboembolism: burden, mechanisms, and management. Thromb Haemost. 2017;117(2):219\u201330.","journal-title":"Thromb Haemost."},{"issue":"6","key":"328_CR2","doi-asserted-by":"publisher","first-page":"1404","DOI":"10.1016\/j.ejca.2012.10.021","volume":"49","author":"AJ Walker","year":"2013","unstructured":"Walker AJ, Card TR, West J, Crooks C, Grainge MJ. Incidence of venous thromboembolism in patients with cancer-a cohort study using linked United Kingdom databases. Eur J Cancer. 2013;49(6):1404\u201313.","journal-title":"Eur J Cancer."},{"issue":"10","key":"328_CR3","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1007\/s00595-004-2842-1","volume":"34","author":"M Sakon","year":"2004","unstructured":"Sakon M, Kakkar AK, Ikeda M, Sekimoto M, Nakamori S, Yano M, Monden M. Current status of pulmonary embolism in general surgery in Japan. 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Front Pediatr. 2018. https:\/\/doi.org\/10.3389\/fped.2018.00142.","DOI":"10.3389\/fped.2018.00142"},{"issue":"3","key":"328_CR6","doi-asserted-by":"publisher","first-page":"978","DOI":"10.4143\/crt.2015.311","volume":"48","author":"E Lee","year":"2016","unstructured":"Lee E, Kang SB, Choi SI, Chun EJ, Kim MJ, Kim DW, Oh HK, Ihn MH, Kim JW, Bang SM, Lee JO, Kim YJ, Kim JH, Lee JS, Lee KW. Prospective study on the incidence of postoperative venous thromboembolism in Korean patients with colorectal cancer. Cancer Res Treat. 2016;48(3):978\u201389.","journal-title":"Cancer Res Treat."},{"issue":"5","key":"328_CR7","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1002\/ags3.12279","volume":"3","author":"T Hata","year":"2019","unstructured":"Hata T, Yasui M, Ikeda M, Miyake M, Ide Y, Okuyama M, Ikenaga M, Kitani K, Morita S, Matsuda C, Mizushima T, Yamamoto H, Murata K, Sekimoto M, Nezu R, Mori M, Doki Y. Efficacy and safety of anticoagulant prophylaxis for prevention of postoperative venous thromboembolism in Japanese patients undergoing laparoscopic colorectal cancer surgery. Ann Gastroenterol Surg. 2019;3(5):568\u201375.","journal-title":"Ann Gastroenterol Surg."},{"issue":"10063","key":"328_CR8","doi-asserted-by":"publisher","first-page":"3060","DOI":"10.1016\/S0140-6736(16)30514-1","volume":"388","author":"M Di Nisio","year":"2016","unstructured":"Di Nisio M, van Es N, B\u00fcller HR. Deep vein thrombosis and pulmonary embolism. Lancet. 2016;388(10063):3060\u201373.","journal-title":"Lancet."},{"issue":"2","key":"328_CR9","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1007\/s00268-015-3234-y","volume":"40","author":"Y Kimura","year":"2016","unstructured":"Kimura Y, Oki E, Ando K, Saeki H, Kusumoto T, Maehara Y. Incidence of venous thromboembolism following laparoscopic surgery for gastrointestinal caner: a single-center, prospective cohort study. 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