{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T07:03:32Z","timestamp":1778828612005,"version":"3.51.4"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T00:00:00Z","timestamp":1661904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T00:00:00Z","timestamp":1661904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["JA Clin Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Congenital myasthenia syndrome is a heterogeneous disease with impaired neuromuscular transmission.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>This report describes a 13-year-old child with congenital myasthenia syndrome who underwent surgery for scoliosis under general anesthesia. We used a small dose of rocuronium, neuromuscular transmission monitoring, and non-invasive positive pressure ventilation for postoperative respiratory management. There were no respiratory complications during the perioperative period.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>As there are only a few reports on the anesthetic management of patients with congenital myasthenia syndrome, we applied the principles of managing autoimmune myasthenia gravis. The postoperative management described herein can prevent respiratory complications in patients with congenital myasthenia syndrome.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40981-022-00560-1","type":"journal-article","created":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T06:04:44Z","timestamp":1661925884000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["General anesthesia for treating scoliosis with congenital myasthenia syndrome: a case report"],"prefix":"10.1186","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6538-2164","authenticated-orcid":false,"given":"Atsushi","family":"Yamashita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuka","family":"Muramatsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotsugu","family":"Okamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,8,31]]},"reference":[{"key":"560_CR1","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.ncl.2020.03.004","volume":"38","author":"SJP Iyadurai","year":"2020","unstructured":"Iyadurai SJP. Congenital myasthenic syndromes. Neurol Clin. 2020;38:541\u201352. https:\/\/doi.org\/10.1016\/j.ncl.2020.03.004.","journal-title":"Neurol Clin"},{"key":"560_CR2","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1097\/00004311-200604420-00006","volume":"44","author":"GN O\u2019Neill","year":"2006","unstructured":"O\u2019Neill GN. Inherited disorders of the neuromuscular junction. Int Anesthesiol Clin. 2006;44:91\u2013106. https:\/\/doi.org\/10.1097\/00004311-200604420-00006.","journal-title":"Int Anesthesiol Clin"},{"key":"560_CR3","first-page":"911","volume":"63","author":"M Emura","year":"2014","unstructured":"Emura M, Ishii H, Baba H. Anesthetic management of scoliosis surgery for a patient with congenital myasthenic syndrome (in Japanese with English abstract). Masui Jpn J Anesthesiol. 2014;63:911\u20134.","journal-title":"Masui Jpn J Anesthesiol"},{"key":"560_CR4","first-page":"49","volume":"20","author":"E Cali\u015fkan","year":"2008","unstructured":"Cali\u015fkan E, Ko\u00e7um A, Sener M, Bozdo\u011fan N, Aribo\u011fan A. Caudal epidural anesthesia for a 2-year old child with congenital myasthenia gravis. Agri. 2008;20:49\u201352.","journal-title":"Agri."},{"key":"560_CR5","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1093\/bja\/77.5.672","volume":"77","author":"C McBeth","year":"1996","unstructured":"McBeth C, Watkins TG. Isoflurane for sedation in a case of congenital myasthenia gravis. Br J Anaesth. 1996;77:672\u20134. https:\/\/doi.org\/10.1093\/bja\/77.5.672.","journal-title":"Br J Anaesth"},{"key":"560_CR6","doi-asserted-by":"publisher","first-page":"e0156","DOI":"10.1097\/MD.0000000000010156","volume":"97","author":"EK Choi","year":"2018","unstructured":"Choi EK, Kwon N, Park SJ. Comparison of the effects of oxycodone versus fentanyl on airway reflex to tracheal extubation and postoperative pain during anesthesia recovery after laparoscopic cholecystectomy: a double-blind, randomized clinical consort study. Medicine (Baltimore). 2018;97:e0156. https:\/\/doi.org\/10.1097\/MD.0000000000010156.","journal-title":"Medicine (Baltimore)"},{"key":"560_CR7","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1111\/j.1399-6576.2011.02558.x","volume":"56","author":"L Blichfeldt-Lauridsen","year":"2012","unstructured":"Blichfeldt-Lauridsen L, Hansen BD. Anesthesia and myasthenia gravis. Acta Anaesthesiol Scand. 2012;56:17\u201322. https:\/\/doi.org\/10.1111\/j.1399-6576.2011.02558.x.","journal-title":"Acta Anaesthesiol Scand"}],"container-title":["JA Clinical Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40981-022-00560-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s40981-022-00560-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s40981-022-00560-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T06:06:53Z","timestamp":1661926013000},"score":1,"resource":{"primary":{"URL":"https:\/\/jaclinicalreports.springeropen.com\/articles\/10.1186\/s40981-022-00560-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,31]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["560"],"URL":"https:\/\/doi.org\/10.1186\/s40981-022-00560-1","relation":{},"ISSN":["2363-9024"],"issn-type":[{"value":"2363-9024","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,31]]},"assertion":[{"value":"22 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 August 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 August 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 August 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient\u2019s parent for publication of this case report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"70"}}