{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:16:13Z","timestamp":1740176173377,"version":"3.37.3"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["JA Clin Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Nausea and vomiting during awake craniotomy (AC) can increase cerebral pressure and cause asphyxia and aspiration. 5-HT3 receptor antagonists, such as granisetron, are often administered before awakening to prevent nausea during AC. Recently, dexamethasone was reported to prevent nausea and vomiting during AC; however, the efficacy of both drugs in preventing nausea has not yet been investigated.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We examined the frequency of nausea and vomiting in AC patients (<jats:italic>n<\/jats:italic>\u2009=\u2009170) treated at our hospital until the end of September 2019. We divided patients as those who received dexamethasone (<jats:italic>n<\/jats:italic>\u2009=\u200971) and or granisetron (<jats:italic>n<\/jats:italic>\u2009=\u200999) before awakening and examined the frequency of nausea and vomiting after propensity score (PS) matching.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Result<\/jats:title>\n                <jats:p>Eighty-two patients were selected after PS matching. The incidence of nausea was significantly lower in the dexamethasone group than in the granisetron group (9.8% vs 41.5%, <jats:italic>p<\/jats:italic>\u2009=\u20090.002). In the logistic regression analysis after matching, the incidence of nausea significantly reduced with dexamethasone treatment (odds ratio: 0.12, 95% confidence interval: 0.029\u20130.499, <jats:italic>p<\/jats:italic>\u2009=\u20090.03).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>In conclusion, dexamethasone was more effective than granisetron in preventing nausea during AC.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s40981-024-00746-9","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T09:02:02Z","timestamp":1728291722000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dexamethasone versus 5-HT3 receptor antagonists in preventing nausea during awake craniotomy: a propensity score matching study"],"prefix":"10.1186","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5025-4250","authenticated-orcid":false,"given":"Takehito","family":"Sato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"key":"746_CR1","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1093\/bja\/aew024","volume":"116","author":"N Goettel","year":"2016","unstructured":"Goettel N, Bharadwaj S, Venkatraghavan L, Mehta J, Bernstein M, Manninen PH. Dexmedetomidine vs. propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial. Br J Anaesth. 2016;116:811\u201321.","journal-title":"Br J Anaesth"},{"key":"746_CR2","doi-asserted-by":"publisher","unstructured":"Sato T, Ando T, Ozeki K, Asano I, Kuwatsuka Y, Ando M, et al. Prospective randomized controlled trial comparing anesthetic management with remimazolam besylate and flumazenil versus propofol during awake craniotomy following an asleep-awake-asleep method. J Neurosurg Anesthesiol. 2024. https:\/\/doi.org\/10.1097\/ANA.0000000000000975. Epub ahead of print.","DOI":"10.1097\/ANA.0000000000000975"},{"issue":"5","key":"746_CR3","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s12630-017-0840-1","volume":"64","author":"L Meng","year":"2017","unstructured":"Meng L, McDonagh DL, Berger MS, Gelb AW. Anesthesia for awake craniotomy: a how-to guide for the occasional practitioner. 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