{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T21:26:19Z","timestamp":1757625979069,"version":"3.44.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T00:00:00Z","timestamp":1755907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T00:00:00Z","timestamp":1755907200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["JA Clin Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Posterior reversible encephalopathy syndrome (PRES) often presents with a wide range of neurological symptoms, and atypical manifestations can complicate its diagnosis. We report a rare case of peripartum PRES presenting with profound transient retrograde amnesia and orofacial automatisms, notably in the absence of generalized seizures.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case presentation<\/jats:title>\n            <jats:p>A 29-year-old primigravida developed sustained hypertension during labor. Immediately postpartum, she experienced visual disturbances, followed by altered consciousness and lip-smacking movements. She subsequently developed profound but transient retrograde amnesia, including loss of autobiographical memory. Brain magnetic resonance imaging (MRI) revealed characteristic findings of PRES in the bilateral parieto-occipital lobes, leading to a diagnosis of PRES secondary to preeclampsia.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Discussion<\/jats:title>\n            <jats:p>This case highlights that peripartum PRES can present with atypical neurological symptoms, such as transient global amnesia and facial automatisms, even in the absence of typical eclamptic seizures. Such presentations warrant a high index of suspicion and prompt brain MRI to ensure accurate diagnosis and timely intervention.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s40981-025-00809-5","type":"journal-article","created":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T03:45:34Z","timestamp":1755920734000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Posterior reversible encephalopathy syndrome during epidural labor analgesia: a case report"],"prefix":"10.1186","volume":"11","author":[{"given":"Sadamu","family":"Sugimoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misako","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Takebe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kousou","family":"Matsuura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0119-3532","authenticated-orcid":false,"given":"Tomonori","family":"Takazawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,8,23]]},"reference":[{"key":"809_CR1","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1056\/NEJM199602223340803","volume":"334","author":"J Hinchey","year":"1996","unstructured":"Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med. 1996;334:494\u2013500.","journal-title":"N Engl J Med"},{"key":"809_CR2","first-page":"1199","volume":"21","author":"SO Casey","year":"2000","unstructured":"Casey SO, Sampaio RC, Michel E, Truwit CL. Posterior reversible encephalopathy syndrome: utility of fluid-attenuated inversion recovery MR imaging in the detection of cortical and subcortical lesions. AJNR Am J Neuroradiol. 2000;21:1199\u2013206.","journal-title":"AJNR Am J Neuroradiol"},{"key":"809_CR3","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1007\/s00134-006-0459-0","volume":"33","author":"G Servillo","year":"2007","unstructured":"Servillo G, Bifulco F, De Robertis E, Piazza O, Striano P, Tortora F, et al. Posterior reversible encephalopathy syndrome in intensive care medicine. Intensive Care Med. 2007;33:230\u20136.","journal-title":"Intensive Care Med"},{"key":"809_CR4","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1136\/jnnp.2009.189647","volume":"81","author":"C Roth","year":"2010","unstructured":"Roth C, Ferbert A. Posterior reversible encephalopathy syndrome: long-term follow-up. J Neurol Neurosurg Psychiatry. 2010;81:773\u20137.","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"809_CR5","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1007\/s00415-016-8377-8","volume":"264","author":"M Fischer","year":"2017","unstructured":"Fischer M, Schmutzhard E. Posterior reversible encephalopathy syndrome. J Neurol. 2017;264:1608\u201316.","journal-title":"J Neurol"},{"issue":"468","key":"809_CR6","first-page":"e1","volume":"208","author":"J Brewer","year":"2013","unstructured":"Brewer J, Owens MY, Wallace K, Reeves AA, Morris R, Khan M, et al. Posterior reversible encephalopathy syndrome in 46 of 47 patients with eclampsia. Am J Obstet Gynecol. 2013;208(468):e1-6.","journal-title":"Am J Obstet Gynecol"},{"key":"809_CR7","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1007\/s13224-019-01214-6","volume":"69","author":"S Sardesai","year":"2019","unstructured":"Sardesai S, Dabade R, Deshmukh S, Patil P, Pawar S, Patil A. Posterior reversible encephalopathy syndrome (PRES): evolving the mystery of eclampsia. J Obstet Gynaecol India. 2019;69:334\u20138.","journal-title":"J Obstet Gynaecol India"},{"key":"809_CR8","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1097\/OGX.0000000000000069","volume":"69","author":"IR Postma","year":"2014","unstructured":"Postma IR, Slager S, Kremer HP, de Groot JC, Zeeman GG. Long-term consequences of the posterior reversible encephalopathy syndrome in eclampsia and preeclampsia: a review of the obstetric and nonobstetric literature. Obstet Gynecol Surv. 2014;69:287\u2013300.","journal-title":"Obstet Gynecol Surv"},{"key":"809_CR9","volume":"11","author":"M Qureshi","year":"2019","unstructured":"Qureshi M, Huang J. Atypical case of posterior reversible encephalopathy in a pregnant patient without preeclampsia. Cureus. 2019;11: e5620.","journal-title":"Cureus"},{"key":"809_CR10","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1136\/practneurol-2021-003194","volume":"22","author":"JD Triplett","year":"2022","unstructured":"Triplett JD, Kutlubaev MA, Kermode AG, Hardy T. Posterior reversible encephalopathy syndrome (PRES): diagnosis and management. Pract Neurol. 2022;22:183\u20139.","journal-title":"Pract Neurol"},{"key":"809_CR11","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.annfar.2010.10.003","volume":"30","author":"B Etesse","year":"2011","unstructured":"Etesse B, Letouzey V, Roger C, Lefauconnier A, Ripart J. L\u2019anesth\u00e9sie p\u00e9ridurale n\u2019est pas la seule cause de troubles neurologiques centraux durant le travail obst\u00e9trical. Un cas de syndrome d\u2019enc\u00e9phalopathie post\u00e9rieure r\u00e9versible. Ann Fr Anesth Reanim. 2011;30:57\u201360.","journal-title":"Ann Fr Anesth Reanim"},{"key":"809_CR12","doi-asserted-by":"publisher","first-page":"71","DOI":"10.3389\/fneur.2020.00071","volume":"11","author":"A Hinduja","year":"2020","unstructured":"Hinduja A. Posterior reversible encephalopathy syndrome: clinical features and outcome. Front Neurol. 2020;11:71.","journal-title":"Front Neurol"},{"key":"809_CR13","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1007\/s00415-011-6362-9","volume":"259","author":"O Kastrup","year":"2012","unstructured":"Kastrup O, Gerwig M, Frings M, Diener HC. Posterior reversible encephalopathy syndrome (PRES): electroencephalographic findings and seizure patterns. 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The study was conducted in accordance with the principles of the Declaration of Helsinki. Written informed consent to participate was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the consent form is available for review by the Editor-in-Chief of this journal upon request.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"46"}}