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The patients were divided into the \u2018good blood glucose control\u2019 group and the \u2018poor blood glucose control\u2019 group based on an assessment of their blood glucose control. The clinical data, computed tomography (CT) appearance and score and the severity of COVID-19 infection of the two groups were compared, with the severity of COVID-19 infection being the dependent variable to analyse other influencing factors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The group with poor blood glucose control showed a higher lobar involvement degree and total CT severity score (CTSS) than the group with good blood glucose control (13.30\u2009\u00b1\u20095.25 vs. 10.38\u2009\u00b1\u20094.84, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The two groups exhibited no statistically significant differences in blood lymphocyte, leukocyte, C-reaction protein, pleural effusion, consolidation, ground glass opacity or crazy-paving signs. Logistic regression analysis showed that the total CTSS significantly influences the clinical severity of patients (odds ratio 1.585, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), whereas fasting plasma glucose and blood glucose control are not independent factors influencing clinical severity (both <jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). The area under the curve (AUC) of CTSS prediction of critical COVID-19 was 0.895 with sensitivity of 79.3% and specificity of 88.1% when the threshold value is 12.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Blood glucose control is significantly correlated with the CTSS; the higher the blood glucose is, the more severe the lung manifestation. The CTSS can also be used to evaluate and predict the clinical severity of COVID-19.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s41043-024-00548-w","type":"journal-article","created":{"date-parts":[[2024,4,23]],"date-time":"2024-04-23T17:02:50Z","timestamp":1713891770000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Severity of COVID-19 infection in patients with COVID-19 combined with diabetes"],"prefix":"10.1186","volume":"43","author":[{"given":"Dan","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengcheng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,23]]},"reference":[{"issue":"1","key":"548_CR1","doi-asserted-by":"publisher","first-page":"2212568","DOI":"10.1080\/21645515.2023.2212568","volume":"19","author":"A Sarkar","year":"2023","unstructured":"Sarkar A, Omar S, Alshareef A, Fanous K, Sarker S, Alroobi H, et al. 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