{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T11:44:03Z","timestamp":1788608643184,"version":"build-2803163510"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T00:00:00Z","timestamp":1718150400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T00:00:00Z","timestamp":1718150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Health Popul Nutr"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The prevalence of Vitamin B12 deficiency is common and is more frequent in low- and middle-income countries with a poor or inadequate diet of animal foods. In Ethiopia, researches related to the status of micronutrients in children are limited. Therefore, this study aimed to assess the prevalence of vitamin B12 deficiency and associated factors among primary school children.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A cross-sectional study design was conducted from January 10-February 30\/2023. A total of 514 students were selected using a systematic random sampling technique. Face-to-face interviews using a structured questionnaire, document review, anthropometric measurement, and laboratory studies were implemented to collect data. Data was analyzed by STATA version 14 and summarized by using frequency tables and graphs. Logistic regression analysis was done to identify factors associated with vitamin B12 Deficiency.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>About 34% of the students were found to have vitamin B12 deficiency. Not Consuming animal products (AOR\u2009=\u20091.83, 95% CI:1.20\u20132.79) and low body mass index (AOR\u2009=\u20091.62, 95% CI:1.05\u20132.47) were associated with vitamin B12 deficiency.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The study revealed a notable high deficiency of vitamin B12 in primary school students. Consumption of animal products and BMI were identified as statically significant associated factors with serum concentration of vitamin B12.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s41043-024-00568-6","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T15:01:56Z","timestamp":1718204516000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Prevalence of vitamin B 12 deficiency and associated factors among primary school children: North East Ethiopia: multicenter cross-sectional study"],"prefix":"10.1186","volume":"43","author":[{"given":"Ermiyas Endewunet","family":"Melaku","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Besufekad Mulugeta","family":"Urgie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alemnesh Tesema","family":"Tilahun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilina Ketema","family":"Assefa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alemayehu Abera","family":"Abebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aklile Semu","family":"Tefera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,12]]},"reference":[{"issue":"5","key":"568_CR1","doi-asserted-by":"publisher","first-page":"552","DOI":"10.3945\/an.115.008201","volume":"6","author":"JL Finkelstein","year":"2015","unstructured":"Finkelstein JL, Layden AJ, Stover PJ. Vitamin B-12 and perinatal health. Adv Nutr. 2015;6(5):552\u201363.","journal-title":"Adv Nutr"},{"issue":"3","key":"568_CR2","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1093\/ajcn\/48.3.852","volume":"48","author":"V Herbert","year":"1988","unstructured":"Herbert V, Vitamin. B-12: plant sources, requirements, and assay. Am J Clin Nutr. 1988;48(3):852\u20138.","journal-title":"Am J Clin Nutr"},{"issue":"4","key":"568_CR3","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1111\/jhn.12541","volume":"31","author":"S Chakraborty","year":"2018","unstructured":"Chakraborty S, Chopra M, Mani K, Giri A, Banerjee P, Sahni N, et al. Prevalence of vitamin B12 deficiency in healthy Indian school-going adolescents from rural and urban localities and its relationship with various anthropometric indices: a cross\u2010sectional study. J Hum Nutr Dietetics. 2018;31(4):513\u201322.","journal-title":"J Hum Nutr Dietetics"},{"issue":"9","key":"568_CR4","doi-asserted-by":"publisher","first-page":"4985","DOI":"10.4103\/jfmpc.jfmpc_712_20","volume":"9","author":"S Umasanker","year":"2020","unstructured":"Umasanker S, Bhakat R, Mehta S, Rathaur VK, Verma PK, Bhat N, et al. Vitamin B12 deficiency in children from Northern India: time to reconsider nutritional handicaps. J Family Med Prim Care. 2020;9(9):4985.","journal-title":"J Family Med Prim Care"},{"issue":"4","key":"568_CR5","doi-asserted-by":"publisher","first-page":"1480","DOI":"10.18203\/2349-3291.ijcp20172690","volume":"4","author":"S Goyal","year":"2017","unstructured":"Goyal S, Tiwari K, Meena P, Malviya S, Asif M. Cobalamin and folate status in malnourished children. 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Ethical clearance and approval to conduct the research was obtained from Debre Berhan University, Asrat Woldeyes Health Science Campus, Institutional Research Review Board (IRB) office. Official letter was written from the IRB office to each primary school prior to conducting the research.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Institutional research review board statement"}},{"value":"Informed written consent was obtained from the parents or guardians who were properly informed of the objectives, methods, and institutional affiliations of the researchers and assured that their responses would be kept anonymous and confidential. Respondents (both guardians and students) were clearly told that they had the right to refuse or terminate at any point of the interview or procedure. Moreover, assent was also obtained from children. The interview and procedures were conducted during a day-off for students.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare that they have no conflict of interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"82"}}